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Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?

Frontiers in oncology, 2018-07, Vol.8, p.267-267

2018

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Targeting Notch to overcome radiation resistance

Oncotarget, 2016-02, Vol.7 (7), p.7610-7628

2016

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Multiplex genetic manipulations in Clostridium butyricum and Clostridium sporogenes to secrete recombinant antigen proteins for oral-spore vaccination

Microbial cell factories, 2024-04, Vol.23 (1), p.119-119

2024

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Efficient Secretion of Murine IL-2 From an Attenuated Strain of Clostridium sporogenes, a Novel Delivery Vehicle for Cancer Immunotherapy

Frontiers in microbiology, 2021-06, Vol.12, p.669488-669488

2021

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Regulated Proteolysis of NOTCH2 and NOTCH3 Receptors by ADAM10 and Presenilins

Molecular and cellular biology, 2014-08, Vol.34 (15), p.2822-2832

2014

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Hypoxia-activated prodrugs and (lack of) clinical progress: The need for hypoxia-based biomarker patient selection in phase III clinical trials

Clinical and translational radiation oncology, 2019-02, Vol.15, p.62-69

2019

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High NOTCH activity induces radiation resistance in non small cell lung cancer

Radiotherapy and oncology, 2013-09, Vol.108 (3), p.440-445

2013

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Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammationin NASH Mice

Frontiers in immunology, 2021-07, Vol.12, p.675535-675535

2021

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Human fibronectin extra domain B as a biomarker for targeted therapy in cancer

Molecular oncology, 2020-07, Vol.14 (7), p.1555-1568

2020

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Hypoxia PET Imaging with [18F]-HX4-A Promising Next-Generation Tracer

Cancers, 2020-05, Vol.12 (5), p.1322

2020

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All Roads Lead to Cathepsins: The Role of Cathepsins in Non-Alcoholic Steatohepatitis-Induced Hepatocellular Carcinoma

Biomedicines, 2022-09, Vol.10 (10), p.2351

2022

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Nutritional Interventions in Cancer Cachexia: Evidence and Perspectives From Experimental Models

Frontiers in nutrition (Lausanne), 2020-12, Vol.7, p.601329-601329

2020

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Homologous Recombination Deficiency Scar: Mutations and Beyond—Implications for Precision Oncology

Cancers, 2022-08, Vol.14 (17), p.4157

2022

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Development of a CRISPR-Cas12a system for efficient genome engineering in clostridia

Microbiology spectrum, 2023-12, Vol.11 (6), p.e0245923-e0245923

2023

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Fatty Acids as a Tool to Boost Cancer Immunotherapy Efficacy

Frontiers in nutrition (Lausanne), 2022-06, Vol.9, p.868436-868436

2022

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Lysine 63-polyubiquitination guards against translesion synthesis-induced mutations

PLoS genetics, 2006-07, Vol.2 (7), p.e116

2006

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Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cures poorly immunogenic tumors when combined with radiotherapy

Journal for immunotherapy of cancer, 2021-03, Vol.9 (3), p.e001764

2021

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Deep Learning Based Automated Orthotopic Lung Tumor Segmentation in Whole-Body Mouse CT-Scans

Cancers, 2021-09, Vol.13 (18), p.4585

2021

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A novel orthotopic mouse model replicates human lung cancer cachexia

Journal of cachexia, sarcopenia and muscle, 2023-06, Vol.14 (3), p.1410-1423

2023

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Use of a Luciferase-Expressing Orthotopic Rat Brain Tumor Model to Optimize a Targeted Irradiation Strategy for Efficacy Testing with Temozolomide

Cancers, 2020-06, Vol.12 (6), p.1585

2020

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The Modulatory Effects of Fatty Acids on Cancer Progression

Biomedicines, 2023-01, Vol.11 (2), p.280

2023

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Diminished Carcinogen Detoxification Is a Novel Mechanism for Hypoxia-inducible Factor 1-mediated Genetic Instability

The Journal of biological chemistry, 2010-05, Vol.285 (19), p.14558-14564

2010

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Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr-/- Mice

PloS one, 2016-11, Vol.11 (11), p.e0167199-e0167199

2016

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Advancing Clostridia to Clinical Trial: Past Lessons and Recent Progress

Cancers, 2016-06, Vol.8 (7), p.63

2016

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Development of a flexible and potent hypoxia-inducible promoter for tumor-targeted gene expression in attenuated salmonella

Cancer biology & therapy, 2006-09, Vol.5 (9), p.1120-1128

2006

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Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?

Targeting Notch to overcome radiation resistance

Multiplex genetic manipulations in Clostridium butyricum and Clostridium sporogenes to secrete recombinant antigen proteins for oral-spore vaccination

Efficient Secretion of Murine IL-2 From an Attenuated Strain of Clostridium sporogenes, a Novel Delivery Vehicle for Cancer Immunotherapy

Regulated Proteolysis of NOTCH2 and NOTCH3 Receptors by ADAM10 and Presenilins

Hypoxia-activated prodrugs and (lack of) clinical progress: The need for hypoxia-based biomarker patient selection in phase III clinical trials

High NOTCH activity induces radiation resistance in non small cell lung cancer

Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammationin NASH Mice

Human fibronectin extra domain B as a biomarker for targeted therapy in cancer

Hypoxia PET Imaging with [18F]-HX4-A Promising Next-Generation Tracer

All Roads Lead to Cathepsins: The Role of Cathepsins in Non-Alcoholic Steatohepatitis-Induced Hepatocellular Carcinoma

Nutritional Interventions in Cancer Cachexia: Evidence and Perspectives From Experimental Models

Homologous Recombination Deficiency Scar: Mutations and Beyond—Implications for Precision Oncology

Development of a CRISPR-Cas12a system for efficient genome engineering in clostridia

Fatty Acids as a Tool to Boost Cancer Immunotherapy Efficacy

Lysine 63-polyubiquitination guards against translesion synthesis-induced mutations

Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cures poorly immunogenic tumors when combined with radiotherapy

Deep Learning Based Automated Orthotopic Lung Tumor Segmentation in Whole-Body Mouse CT-Scans

A novel orthotopic mouse model replicates human lung cancer cachexia

Use of a Luciferase-Expressing Orthotopic Rat Brain Tumor Model to Optimize a Targeted Irradiation Strategy for Efficacy Testing with Temozolomide

The Modulatory Effects of Fatty Acids on Cancer Progression

Diminished Carcinogen Detoxification Is a Novel Mechanism for Hypoxia-inducible Factor 1-mediated Genetic Instability

Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr-/- Mice

Advancing Clostridia to Clinical Trial: Past Lessons and Recent Progress

Development of a flexible and potent hypoxia-inducible promoter for tumor-targeted gene expression in attenuated salmonella

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