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In vivo generated human CAR T cells eradicate tumor cells

Oncoimmunology, 2019-12, Vol.8 (12), p.e1671761-e1671761

2019

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In vivo generation of human CD19‐CAR T cells results in B‐cell depletion and signs of cytokine release syndrome

EMBO molecular medicine, 2018-11, Vol.10 (11), p.1-n/a

2018

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Highly Efficient Generation of Transgenically Augmented CAR NK Cells Overexpressing CXCR4

Frontiers in immunology, 2020-08, Vol.11, p.2028-2028

2020

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Early induction of cytokine release syndrome by rapidly generated CAR T cells in preclinical models

EMBO molecular medicine, 2024-04, Vol.16 (4), p.784-804

2024

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CD62L as target receptor for specific gene delivery into less differentiated human T lymphocytes

Frontiers in immunology, 2023-08, Vol.14, p.1183698

2023

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Incomplete cytokinesis and re-fusion of small mononucleated Hodgkin cells lead to giant multinucleated Reed—Sternberg cells

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (51), p.20729-20734

2013

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Tumor-Specific Delivery of Immune Checkpoint Inhibitors by Engineered AAV Vectors

Frontiers in oncology, 2019-02, Vol.9, p.52-52

2019

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In vivo generation of CAR T cells in the presence of human myeloid cells

Molecular therapy. Methods & clinical development, 2022-09, Vol.26, p.144-156

2022

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Monitoring CAR T cell generation with a CD8-targeted lentiviral vector by single-cell transcriptomics

Molecular therapy. Methods & clinical development, 2021-12, Vol.23, p.359-369

2021

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Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal

Cell reports (Cambridge), 2015-06, Vol.11 (12), p.1847-1855

2015

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CAR Gene Delivery by T‐cell Targeted Lentiviral Vectors is Enhanced by Rapamycin Induced Reduction of Antiviral Mechanisms

Advanced science, 2023-12, Vol.10 (35), p.e2302992-n/a

2023

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In Vivo Generation of CAR T Cells Selectively in Human CD4+ Lymphocytes

Molecular therapy, 2020-08, Vol.28 (8), p.1783-1794

2020

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The functional interplay between the t(9;22)-associated fusion proteins BCR/ABL and ABL/BCR in Philadelphia chromosome-positive acute lymphatic leukemia

PLoS genetics, 2015-04, Vol.11 (4), p.e1005144-e1005144

2015

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Cytokine-Regulated GADD45G Induces Differentiation and Lineage Selection in Hematopoietic Stem Cells

Stem cell reports, 2014-07, Vol.3 (1), p.34-43

2014

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Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells

Nature (London), 2015-04, Vol.520 (7548), p.549-552

2015

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DNA‐damage response gene GADD45A induces differentiation in hematopoietic stem cells without inhibiting cell cycle or survival

Stem cells (Dayton, Ohio), 2016-03, Vol.34 (3), p.699-710

2016

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AAV vectors displaying bispecific DARPins enable dual-control targeted gene delivery

Biomaterials, 2023-12, Vol.303, p.122399-122399, Article 122399

2023

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STAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling

Nature communications, 2015-11, Vol.6 (1), p.8928-8928, Article 8928

2015

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T-cell specific in vivo gene delivery with DART-AAVs targeted to CD8

Molecular therapy, 2024-10, Vol.32 (10), p.3470-3484

2024

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Combining T-cell–specific activation and in vivo gene delivery through CD3-targeted lentiviral vectors

Blood advances, 2020-11, Vol.4 (22), p.5702-5715

2020

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1260 Rapid cytokine release syndrome caused by short-term CAR T cells in a preclinical mouse model

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1395-A1395

2023

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Monitoring CAR T cell generation with a CD8-targeted lentiviral vector by single-cell transcriptomics

Molecular therapy. Methods & clinical development, 2022-03, Vol.24, p.207-209

2022

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GluA4-Targeted AAV Vectors Deliver Genes Selectively to Interneurons while Relying on the AAV Receptor for Entry

Molecular therapy. Methods & clinical development, 2019-09, Vol.14, p.252-260

2019

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Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy

In vivo generated human CAR T cells eradicate tumor cells

In vivo generation of human CD19‐CAR T cells results in B‐cell depletion and signs of cytokine release syndrome

Highly Efficient Generation of Transgenically Augmented CAR NK Cells Overexpressing CXCR4

Early induction of cytokine release syndrome by rapidly generated CAR T cells in preclinical models

CD62L as target receptor for specific gene delivery into less differentiated human T lymphocytes

Incomplete cytokinesis and re-fusion of small mononucleated Hodgkin cells lead to giant multinucleated Reed—Sternberg cells

Tumor-Specific Delivery of Immune Checkpoint Inhibitors by Engineered AAV Vectors

In vivo generation of CAR T cells in the presence of human myeloid cells

Monitoring CAR T cell generation with a CD8-targeted lentiviral vector by single-cell transcriptomics

Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal

CAR Gene Delivery by T‐cell Targeted Lentiviral Vectors is Enhanced by Rapamycin Induced Reduction of Antiviral Mechanisms

In Vivo Generation of CAR T Cells Selectively in Human CD4+ Lymphocytes

The functional interplay between the t(9;22)-associated fusion proteins BCR/ABL and ABL/BCR in Philadelphia chromosome-positive acute lymphatic leukemia

Cytokine-Regulated GADD45G Induces Differentiation and Lineage Selection in Hematopoietic Stem Cells

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells

DNA‐damage response gene GADD45A induces differentiation in hematopoietic stem cells without inhibiting cell cycle or survival

AAV vectors displaying bispecific DARPins enable dual-control targeted gene delivery

STAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling

T-cell specific in vivo gene delivery with DART-AAVs targeted to CD8

Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain

Combining T-cell–specific activation and in vivo gene delivery through CD3-targeted lentiviral vectors

1260 Rapid cytokine release syndrome caused by short-term CAR T cells in a preclinical mouse model

Monitoring CAR T cell generation with a CD8-targeted lentiviral vector by single-cell transcriptomics

GluA4-Targeted AAV Vectors Deliver Genes Selectively to Interneurons while Relying on the AAV Receptor for Entry

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