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Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders

The Journal of experimental medicine, 2017-11, Vol.214 (11), p.3219-3238

2017

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Structural Basis of Potential Inhibitors Targeting SARS-CoV-2 Main Protease

Frontiers in chemistry, 2021-03, Vol.9, p.622898-622898

2021

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Pharmacological Inhibitors of the NLRP3 Inflammasome

Frontiers in immunology, 2019-10, Vol.10, p.2538

2019

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Orchestration of NLRP3 Inflammasome Activation by Ion Fluxes

Trends in immunology, 2018-05, Vol.39 (5), p.393-406

2018

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TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity

The Journal of experimental medicine, 2017-02, Vol.214 (2), p.459-473

2017

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Pattern recognition receptors in zebrafish provide functional and evolutionary insight into innate immune signaling pathways

Cellular & molecular immunology, 2017-01, Vol.14 (1), p.80-89

2017

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Structural Immunology

1st ed. 2019., 2019

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Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm

Nature communications, 2020-08, Vol.11 (1), p.3924-11, Article 3924

2020

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Serum IgA, IgM, and IgG responses in COVID-19

Cellular & molecular immunology, 2020-07, Vol.17 (7), p.773-775

2020

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Biochemical characterization of SARS-CoV-2 nucleocapsid protein

Biochemical and biophysical research communications, 2020-06, Vol.527 (3), p.618-623

2020

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Molecular and Structural Basis of DNA Sensors in Antiviral Innate Immunity

Frontiers in immunology, 2020-11, Vol.11, p.613039-613039

2020

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IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (48), p.E4571-E4580

2013

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Epidemiology and Burden of Human Papillomavirus and Related Diseases, Molecular Pathogenesis, and Vaccine Evaluation

Frontiers in public health, 2021-01, Vol.8, p.552028-552028

2021

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Endothelial Cells as a Key Cell Type for Innate Immunity: A Focused Review on RIG-I Signaling Pathway

Frontiers in immunology, 2022-07, Vol.13, p.951614-951614

2022

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Profiling CD8+ T cell epitopes of COVID-19 convalescents reveals reduced cellular immune responses to SARS-CoV-2 variants

Cell reports (Cambridge), 2021-09, Vol.36 (11), p.109708-109708, Article 109708

2021

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Activation and Immune Regulation Mechanisms of PYHIN Family During Microbial Infection

Frontiers in microbiology, 2022-01, Vol.12, p.809412-809412

2022

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Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity

Nature cell biology, 2020-06, Vol.22 (6), p.716-727

2020

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Editorial: Host-microbe interaction in SARS-CoV-2 infection: mechanism and intervention

Frontiers in immunology, 2023-04, Vol.14, p.1198868-1198868

2023

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Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA

Nature immunology, 2015-10, Vol.16 (10), p.1025-1033

2015

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IFI16 is an innate immune sensor for intracellular DNA

Nature immunology, 2010-11, Vol.11 (11), p.997-1004

2010

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Potency, Safety, and Pharmacokinetic Profiles of Potential Inhibitors Targeting SARS-CoV-2 Main Protease

Frontiers in pharmacology, 2021-02, Vol.11, p.630500

2021

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Inflammasomes cross-talk with lymphocytes to connect the innate and adaptive immune response

Journal of advanced research, 2023-12, Vol.54, p.181-193

2023

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Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

Immunity (Cambridge, Mass.), 2012-04, Vol.36 (4), p.561-571

2012

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Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome

Cell death & disease, 2021-01, Vol.12 (1), p.57-57, Article 57

2021

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Re-detectable positive SARS-CoV-2 RNA tests in patients who recovered from COVID-19 with intestinal infection

Protein & cell, 2021-03, Vol.12 (3), p.230-235

2021

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Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders

Structural Basis of Potential Inhibitors Targeting SARS-CoV-2 Main Protease

Pharmacological Inhibitors of the NLRP3 Inflammasome

Orchestration of NLRP3 Inflammasome Activation by Ion Fluxes

TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity

Pattern recognition receptors in zebrafish provide functional and evolutionary insight into innate immune signaling pathways

Structural Immunology

Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm

Serum IgA, IgM, and IgG responses in COVID-19

Biochemical characterization of SARS-CoV-2 nucleocapsid protein

Molecular and Structural Basis of DNA Sensors in Antiviral Innate Immunity

IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication

Epidemiology and Burden of Human Papillomavirus and Related Diseases, Molecular Pathogenesis, and Vaccine Evaluation

Endothelial Cells as a Key Cell Type for Innate Immunity: A Focused Review on RIG-I Signaling Pathway

Profiling CD8+ T cell epitopes of COVID-19 convalescents reveals reduced cellular immune responses to SARS-CoV-2 variants

Activation and Immune Regulation Mechanisms of PYHIN Family During Microbial Infection

Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity

Editorial: Host-microbe interaction in SARS-CoV-2 infection: mechanism and intervention

Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA

IFI16 is an innate immune sensor for intracellular DNA

Potency, Safety, and Pharmacokinetic Profiles of Potential Inhibitors Targeting SARS-CoV-2 Main Protease

Inflammasomes cross-talk with lymphocytes to connect the innate and adaptive immune response

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome

Re-detectable positive SARS-CoV-2 RNA tests in patients who recovered from COVID-19 with intestinal infection

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