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Correlation between an automated functional assay that predicts targeted agent (TA) sensitivity and the tumor response of the sorafenib treatment evaluated within the MOST clinical trial

Annals of oncology, 2018-09, Vol.29, p.vi15-vi16

2018

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64P Identification of the functional significance of mutations using the novel Precision Cancer Analysis System

Journal of thoracic oncology, 2016-04, Vol.11 (4), p.S82-S82

2016

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8P A gradient boosting decision tree (GBDT) approach to identify potential therapeutic targets

Annals of oncology, 2022-10, Vol.33, p.S1386-S1386

2022

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Large scale functional characterization of mutations and their susceptibility to targeted therapy

Annals of oncology, 2019-11, Vol.30, p.vii34

2019

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Interim results from a phase 1/2 precision medicine study of PLX8394- a next generation BRAF inhibitor

European journal of cancer (1990), 2020-10, Vol.138, p.S2-S3

2020

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Functional characterization of mutations and their interaction using the novel functional annotation for cancer treatment (FACT) platform

Annals of oncology, 2016-10, Vol.27, p.vi404-vi404

2016

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Functional profiling of oncogenic mutations in lung cancer patients (NCT02274025) - interim results

Annals of oncology, 2016-10, Vol.27, p.vi412-vi412

2016

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Retrospective analysis of a SHIVA01 trial cohort using functional mutational analysis successfully predicted treatment outcome

Annals of oncology, 2017-09, Vol.28, p.v450-v451

2017

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11LBA - Functional mutational analysis to assess the oncogenic activity of variant of uncertain significance (VUS) detected in patients included in the SHIVA trial

European journal of cancer (1990), 2016-12, Vol.69, p.S6-S7

2016

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Functional characterization of variants of unknown significance (VUS) in patients and their responsiveness to targeted therapy drugs (TTD)

Annals of oncology, 2016-10, Vol.27, p.vi403-vi403

2016

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MHC Class I-Independent Recognition of NK-Activating Receptor KIR2DS4

The Journal of immunology (1950), 2004-08, Vol.173 (3), p.1819-1825

2004

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116PLarge scale functional characterization of mutations and their susceptibility to targeted therapy

Annals of oncology, 2019-11, Vol.30 (Supplement_7)

2019

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44PCorrelation between an automated functional assay that predicts targeted agent (TA) sensitivity and the tumor response of the sorafenib treatment evaluated within the MOST clinical trial

Annals of oncology, 2018-09, Vol.29 (suppl_6)

2018

Volltextzugriff (PDF)

Identification of the functional significance of mutations using the novel Precision Cancer Analysis System: 64P

Journal of thoracic oncology, 2016-04, Vol.11 (4 Suppl), p.S82-S82

2016

Volltextzugriff (PDF)

Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers

Oncogene, 2018-03, Vol.37 (12), p.1669-1684

2018

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RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer

Cell reports (Cambridge), 2016-02, Vol.14 (6), p.1462-1476

2016

Volltextzugriff (PDF)

RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer

Cell death and differentiation, 2017-04, Vol.24 (4), p.694-704

2017

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Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

Cancer cell, 2013-05, Vol.23 (5), p.634-646

2013

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Colocalized targeting of TGF-β and PD-L1 by bintrafusp alfa elicits distinct antitumor responses

Journal for immunotherapy of cancer, 2022-07, Vol.10 (7), p.e004122

2022

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EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors

Science signaling, 2010-06, Vol.3 (124), p.ra43

2010

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OP0197 CGEN-15001, A Novel Negative Co-Stimulator Fusion Protein is Effective in the Collagen-Induced Arthritis Mouse Model of Rheumatoid Arthritis

Annals of the rheumatic diseases, 2013-06, Vol.72 (Suppl 3), p.A119-A119

2013

Volltextzugriff (PDF)

In vitro functional analysis of HER2 variants in lung cancers to evaluate their oncogenic activity and predict clinical response to HER2 targeted therapies

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.e23150-e23150

2017

Volltextzugriff (PDF)

Prenatal Stress Depresses Immune Function in Rats

Physiology & behavior, 1998-02, Vol.63 (3), p.397-402

1998

Volltextzugriff (PDF)

Mutant p53 Prolongs NF-kB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

Cancer cell, 2013-08, Vol.24 (2), p.272-272

2013

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A role for CdxA in gut closure and intestinal epithelia differentiation

Development (Cambridge), 1994-02, Vol.120 (2), p.253-263

1994

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Correlation between an automated functional assay that predicts targeted agent (TA) sensitivity and the tumor response of the sorafenib treatment evaluated within the MOST clinical trial

64P Identification of the functional significance of mutations using the novel Precision Cancer Analysis System

8P A gradient boosting decision tree (GBDT) approach to identify potential therapeutic targets

Large scale functional characterization of mutations and their susceptibility to targeted therapy

Interim results from a phase 1/2 precision medicine study of PLX8394- a next generation BRAF inhibitor

Functional characterization of mutations and their interaction using the novel functional annotation for cancer treatment (FACT) platform

Functional profiling of oncogenic mutations in lung cancer patients (NCT02274025) - interim results

Retrospective analysis of a SHIVA01 trial cohort using functional mutational analysis successfully predicted treatment outcome

11LBA - Functional mutational analysis to assess the oncogenic activity of variant of uncertain significance (VUS) detected in patients included in the SHIVA trial

Functional characterization of variants of unknown significance (VUS) in patients and their responsiveness to targeted therapy drugs (TTD)

MHC Class I-Independent Recognition of NK-Activating Receptor KIR2DS4

116PLarge scale functional characterization of mutations and their susceptibility to targeted therapy

44PCorrelation between an automated functional assay that predicts targeted agent (TA) sensitivity and the tumor response of the sorafenib treatment evaluated within the MOST clinical trial

Identification of the functional significance of mutations using the novel Precision Cancer Analysis System: 64P

Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers

RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer

RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer

Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

Colocalized targeting of TGF-β and PD-L1 by bintrafusp alfa elicits distinct antitumor responses

EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors

OP0197 CGEN-15001, A Novel Negative Co-Stimulator Fusion Protein is Effective in the Collagen-Induced Arthritis Mouse Model of Rheumatoid Arthritis

In vitro functional analysis of HER2 variants in lung cancers to evaluate their oncogenic activity and predict clinical response to HER2 targeted therapies

Prenatal Stress Depresses Immune Function in Rats

Mutant p53 Prolongs NF-kB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

A role for CdxA in gut closure and intestinal epithelia differentiation

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