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Potentiometric and spectrophotometric pKa determination of water-insoluble compounds : Validation study in a new cosolvent system

Analytica chimica acta, 2007-02, Vol.583 (2), p.418-428

2007

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Correlations between Cytotoxicity and Topography of Some 2-Arylidenebenzocycloalkanones Determined by X-ray Crystallography

Journal of medicinal chemistry, 2002-07, Vol.45 (14), p.3103-3111

2002

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Theoretical Conformational Analysis for Neurotransmitters in the Gas Phase and in Aqueous Solution. Norepinephrine

Journal of the American Chemical Society, 2003-03, Vol.125 (9), p.2770-2785

2003

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Protonation Equilibria of Quinolone Antibacterials

Journal of pharmaceutical sciences, 1990-11, Vol.79 (11), p.1023-1028

1990

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Physicochemical Properties of a New Multicomponent Cosolvent System for the pKa Determination of Poorly Soluble Pharmaceutical Compounds

Helvetica chimica acta, 2007-08, Vol.90 (8), p.1538-1553

2007

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Tautomeric and conformational equilibria of tyramine and dopamine in aqueous solution

Molecular physics, 2005-06, Vol.103 (11-12), p.1589-1601

2005

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Prediction of Bioequivalence and Food Effect Using Flux- and Solubility-Based Methods

Molecular pharmaceutics, 2019-10, Vol.16 (10), p.4121-4130

2019

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Study of equilibrium solubility measurement by saturation shake-flask method using hydrochlorothiazide as model compound

Journal of pharmaceutical and biomedical analysis, 2008-01, Vol.46 (2), p.335-341

2008

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In vitro and in silico evaluation of Ononis isoflavonoids as molecules targeting the central nervous system

PloS one, 2022-03, Vol.17 (3), p.e0265639-e0265639

2022

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Synthesis and Biological Characterization of 1-Methyl-1,2,5,6-tetrahydropyridyl-1,2,5-thiadiazole Derivatives as Muscarinic Agonists for the Treatment of Neurological Disorders

Journal of medicinal chemistry, 2003-09, Vol.46 (20), p.4273-4286

2003

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Theoretical and Experimental Studies of the Zwitterion ⇌ Neutral Form Equilibrium of Ampholytes in Pure Solvents and Mixtures

Journal of the American Chemical Society, 1997-05, Vol.119 (21), p.4999-5006

1997

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Towards a Better Understanding of the Post-Gastric Behavior of Enteric-Coated Formulations

Pharmaceutical research, 2022, Vol.39 (1), p.201-211

2022

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Investigation of the Efficacy of Transdermal Penetration Enhancers Through the Use of Human Skin and a Skin Mimic Artificial Membrane

Journal of pharmaceutical sciences, 2016-03, Vol.105 (3), p.1134-1140

2016

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Study of pH-dependent solubility of organic bases. Revisit of Henderson-Hasselbalch relationship

Analytica chimica acta, 2010-07, Vol.673 (1), p.40-46

2010

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Effect of Formulation Additives on Drug Transport through Size-Exclusion Membranes

Molecular pharmaceutics, 2018-08, Vol.15 (8), p.3308-3317

2018

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Multi-Compartmental Dissolution Method, an Efficient Tool for the Development of Enhanced Bioavailability Formulations Containing Poorly Soluble Acidic Drugs

Pharmaceutics, 2023-02, Vol.15 (3), p.753

2023

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The Effect of the Particle Size Reduction on the Biorelevant Solubility and Dissolution of Poorly Soluble Drugs with Different Acid-Base Character

Pharmaceutics, 2023-01, Vol.15 (1), p.278

2023

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Use of an In Vitro Skin Parallel Artificial Membrane Assay (Skin-PAMPA) as a Screening Tool to Compare Transdermal Permeability of Model Compound 4-Phenylethyl-Resorcinol Dissolved in Different Solvents

Pharmaceutics, 2021-10, Vol.13 (11), p.1758

2021

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Understanding the pH Dependence of Supersaturation State—A Case Study of Telmisartan

Pharmaceutics, 2022-08, Vol.14 (8), p.1635

2022

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In vitro and in silico evaluation of Ononis isoflavonoids as molecules targeting the central nervous system

PloS one, 2022-01, Vol.17 (3), p.e0265639

2022

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Equilibrium versus kinetic measurements of aqueous solubility, and the ability of compounds to supersaturate in solution—a validation study

Journal of pharmaceutical sciences, 2006-06, Vol.95 (6), p.1298-1307

2006

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pH–Metric log P. 6. Effects of Sodium, Potassium, and N-CH3-D-Glucamine on the Octanol-Water Partitioning of Prostaglandins E1 and E2

Journal of pharmaceutical sciences, 1995-05, Vol.84 (5), p.523-529

1995

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Multiwavelength spectrophotometric determination of acid dissociation constants

Journal of pharmaceutical and biomedical analysis, 2000-01, Vol.21 (6), p.1171-1182

2000

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Diazo Transfer−Click Reaction Route to New, Lipophilic Teicoplanin and Ristocetin Aglycon Derivatives with High Antibacterial and Anti-influenza Virus Activity: An Aggregation and Receptor Binding Study

Journal of medicinal chemistry, 2009-10, Vol.52 (19), p.6053-6061

2009

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A PAMPA Study of the Permeability-Enhancing Effect of New Ceramide Analogues

Chemistry & biodiversity, 2009-11, Vol.6 (11), p.1867-1874

2009

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Potentiometric and spectrophotometric pKa determination of water-insoluble compounds : Validation study in a new cosolvent system

Correlations between Cytotoxicity and Topography of Some 2-Arylidenebenzocycloalkanones Determined by X-ray Crystallography

Theoretical Conformational Analysis for Neurotransmitters in the Gas Phase and in Aqueous Solution. Norepinephrine

Protonation Equilibria of Quinolone Antibacterials

Physicochemical Properties of a New Multicomponent Cosolvent System for the pKa Determination of Poorly Soluble Pharmaceutical Compounds

Tautomeric and conformational equilibria of tyramine and dopamine in aqueous solution

Prediction of Bioequivalence and Food Effect Using Flux- and Solubility-Based Methods

Study of equilibrium solubility measurement by saturation shake-flask method using hydrochlorothiazide as model compound

In vitro and in silico evaluation of Ononis isoflavonoids as molecules targeting the central nervous system

Synthesis and Biological Characterization of 1-Methyl-1,2,5,6-tetrahydropyridyl-1,2,5-thiadiazole Derivatives as Muscarinic Agonists for the Treatment of Neurological Disorders

Theoretical and Experimental Studies of the Zwitterion ⇌ Neutral Form Equilibrium of Ampholytes in Pure Solvents and Mixtures

Towards a Better Understanding of the Post-Gastric Behavior of Enteric-Coated Formulations

Investigation of the Efficacy of Transdermal Penetration Enhancers Through the Use of Human Skin and a Skin Mimic Artificial Membrane

Study of pH-dependent solubility of organic bases. Revisit of Henderson-Hasselbalch relationship

Effect of Formulation Additives on Drug Transport through Size-Exclusion Membranes

Multi-Compartmental Dissolution Method, an Efficient Tool for the Development of Enhanced Bioavailability Formulations Containing Poorly Soluble Acidic Drugs

The Effect of the Particle Size Reduction on the Biorelevant Solubility and Dissolution of Poorly Soluble Drugs with Different Acid-Base Character

Use of an In Vitro Skin Parallel Artificial Membrane Assay (Skin-PAMPA) as a Screening Tool to Compare Transdermal Permeability of Model Compound 4-Phenylethyl-Resorcinol Dissolved in Different Solvents

Understanding the pH Dependence of Supersaturation State—A Case Study of Telmisartan

In vitro and in silico evaluation of Ononis isoflavonoids as molecules targeting the central nervous system

Equilibrium versus kinetic measurements of aqueous solubility, and the ability of compounds to supersaturate in solution—a validation study

pH–Metric log P. 6. Effects of Sodium, Potassium, and N-CH3-D-Glucamine on the Octanol-Water Partitioning of Prostaglandins E1 and E2

Multiwavelength spectrophotometric determination of acid dissociation constants

Diazo Transfer−Click Reaction Route to New, Lipophilic Teicoplanin and Ristocetin Aglycon Derivatives with High Antibacterial and Anti-influenza Virus Activity: An Aggregation and Receptor Binding Study

A PAMPA Study of the Permeability-Enhancing Effect of New Ceramide Analogues

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