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Modeling Approach to Predict the Impact of Inflammation on the Pharmacokinetics of CYP2C19 and CYP3A4 Substrates

Pharmaceutical research, 2021-03, Vol.38 (3), p.415-428

2021

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Quantitative Prediction of Drug Interactions Caused by CYP1A2 Inhibitors and Inducers

Clinical pharmacokinetics, 2016-08, Vol.55 (8), p.977-990

2016

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Early sorafenib-induced toxicity is associated with drug exposure and UGTIA9 genetic polymorphism in patients with solid tumors: a preliminary study

PloS one, 2012-08, Vol.7 (8), p.e42875

2012

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Association between voriconazole exposure and Sequential Organ Failure Assessment (SOFA) score in critically ill patients

PloS one, 2021-11, Vol.16 (11), p.e0260656

2021

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Covariate analysis of tusamitamab ravtansine, a DM4 anti‐CEACAM5 antibody‐drug conjugate, based on first‐in‐human study

CPT: pharmacometrics and systems pharmacology, 2022-03, Vol.11 (3), p.384-394

2022

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Impact of interleukin‐6 on drug transporters and permeability in the hCMEC/D3 blood–brain barrier model

Fundamental & clinical pharmacology, 2021-04, Vol.35 (2), p.397-409

2021

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Impact of the use of a drug–drug interaction checker on pharmacist interventions involving well-known strong interactors

European journal of hospital pharmacy. Science and practice, 2024-08, p.ejhpharm-2023-004052

2024

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Consequences of Renal Failure on Non-Renal Clearance of Drugs

Clinical pharmacokinetics, 2014-06, Vol.53 (6), p.521-532

2014

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Therapeutic Drug Monitoring and Pharmacogenetic Testing as Guides to Psychotropic Drug Dose Adjustment: An Observational Study

Pharmaceuticals (Basel, Switzerland), 2023-12, Vol.17 (1), p.21

2023

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Drug interactions between emergency contraceptive drugs and cytochrome inducers: literature review and quantitative prediction

Fundamental & clinical pharmacology, 2021-04, Vol.35 (2), p.208-216

2021

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In Silico Evaluation of Pharmacokinetic Optimization for Antimitogram-Based Clinical Trials

Cancer research (Chicago, Ill.), 2018-04, Vol.78 (7), p.1873-1882

2018

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Integrated multiple analytes and semi-mechanistic population pharmacokinetic model of tusamitamab ravtansine, a DM4 anti-CEACAM5 antibody-drug conjugate

Journal of pharmacokinetics and pharmacodynamics, 2022-06, Vol.49 (3), p.381-394

2022

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Potential drug–drug interactions associated with drugs currently proposed for COVID‐19 treatment in patients receiving other treatments

Fundamental & clinical pharmacology, 2020-10, Vol.34 (5), p.530-547

2020

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Pharmacogenetic-guided glimepiride therapy in type-2 diabetes mellitus: a cost-effectiveness study

The pharmacogenomics journal, 2021-10, Vol.21 (5), p.559-565

2021

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Impact of Interleukin-6 on Drug-Metabolizing Enzymes and Transporters in Intestinal Cells

The AAPS journal, 2019-12, Vol.22 (1), p.16, Article 16

2019

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Influence of Burns on Pharmacokinetics and Pharmacodynamics of Drugs Used in the Care of Burn Patients

Clinical pharmacokinetics, 2008-01, Vol.47 (10), p.635-654

2008

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Over-adherence to capecitabine: a potential safety issue in breast and colorectal cancer patients

Cancer chemotherapy and pharmacology, 2018-08, Vol.82 (2), p.319-327

2018

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Validation of an online tool for early prediction of the failure-risk in gestational trophoblastic neoplasia patients treated with methotrexate

Cancer chemotherapy and pharmacology, 2020-07, Vol.86 (1), p.15-24

2020

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Systematic review of artesunate pharmacokinetics: Implication for treatment of resistant malaria

International journal of infectious diseases, 2019-12, Vol.89, p.30-44

2019

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Modeled Early Longitudinal PSA Kinetics Prognostic Value in Rising PSA Prostate Cancer Patients after Local Therapy Treated with ADT +/- Docetaxel

Cancers, 2022-02, Vol.14 (3), p.815

2022

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Variability of Sorafenib Toxicity and Exposure over Time: A Pharmacokinetic/Pharmacodynamic Analysis

The oncologist (Dayton, Ohio), 2012-09, Vol.17 (9), p.1204-1212

2012

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Is there an Exposure-Response Relationship for Nivolumab in Real-World NSCLC Patients?

Cancers, 2019-11, Vol.11 (11), p.1784

2019

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Understanding polyspecificity within the substrate‐binding cavity of the human multidrug resistance P‐glycoprotein

The FEBS journal, 2014-02, Vol.281 (3), p.673-682

2014

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Translational approach from preclinical to clinical: comparison of dose finding methods of a new Bcl2 inhibitor using PK-PD modeling and interspecies extrapolation

Investigational new drugs, 2020-12, Vol.38 (6), p.1796-1806

2020

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Modeling Approach to Predict the Impact of Inflammation on the Pharmacokinetics of CYP2C19 and CYP3A4 Substrates

Quantitative Prediction of Drug Interactions Caused by CYP1A2 Inhibitors and Inducers

Early sorafenib-induced toxicity is associated with drug exposure and UGTIA9 genetic polymorphism in patients with solid tumors: a preliminary study

The Increasing Prognostic and Predictive Roles of the Tumor Primary Chemosensitivity Assessed by CA-125 Elimination Rate Constant K (KELIM) in Ovarian Cancer: A Narrative Review

Association between voriconazole exposure and Sequential Organ Failure Assessment (SOFA) score in critically ill patients

Covariate analysis of tusamitamab ravtansine, a DM4 anti‐CEACAM5 antibody‐drug conjugate, based on first‐in‐human study

Impact of interleukin‐6 on drug transporters and permeability in the hCMEC/D3 blood–brain barrier model

Impact of the use of a drug–drug interaction checker on pharmacist interventions involving well-known strong interactors

Consequences of Renal Failure on Non-Renal Clearance of Drugs

Therapeutic Drug Monitoring and Pharmacogenetic Testing as Guides to Psychotropic Drug Dose Adjustment: An Observational Study

Drug interactions between emergency contraceptive drugs and cytochrome inducers: literature review and quantitative prediction

In Silico Evaluation of Pharmacokinetic Optimization for Antimitogram-Based Clinical Trials

Integrated multiple analytes and semi-mechanistic population pharmacokinetic model of tusamitamab ravtansine, a DM4 anti-CEACAM5 antibody-drug conjugate

Potential drug–drug interactions associated with drugs currently proposed for COVID‐19 treatment in patients receiving other treatments

Pharmacogenetic-guided glimepiride therapy in type-2 diabetes mellitus: a cost-effectiveness study

Impact of Interleukin-6 on Drug-Metabolizing Enzymes and Transporters in Intestinal Cells

Influence of Burns on Pharmacokinetics and Pharmacodynamics of Drugs Used in the Care of Burn Patients

Over-adherence to capecitabine: a potential safety issue in breast and colorectal cancer patients

Validation of an online tool for early prediction of the failure-risk in gestational trophoblastic neoplasia patients treated with methotrexate

Systematic review of artesunate pharmacokinetics: Implication for treatment of resistant malaria

Modeled Early Longitudinal PSA Kinetics Prognostic Value in Rising PSA Prostate Cancer Patients after Local Therapy Treated with ADT +/- Docetaxel

Variability of Sorafenib Toxicity and Exposure over Time: A Pharmacokinetic/Pharmacodynamic Analysis

Is there an Exposure-Response Relationship for Nivolumab in Real-World NSCLC Patients?

Understanding polyspecificity within the substrate‐binding cavity of the human multidrug resistance P‐glycoprotein

Translational approach from preclinical to clinical: comparison of dose finding methods of a new Bcl2 inhibitor using PK-PD modeling and interspecies extrapolation

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