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Combination of tyrosine kinase inhibitors and the MCL1 inhibitor S63845 exerts synergistic antitumorigenic effects on CML cells

Cell death & disease, 2021-09, Vol.12 (10), p.875-875, Article 875

2021

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Specific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia

Leukemia, 2020-08, Vol.34 (8), p.2087-2101

2020

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Decreased incidence of acute immune thrombocytopenia in children during the COVID-19 pandemic

International journal of hematology, 2023-02, Vol.117 (2), p.307-308

2023

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Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia

The Journal of steroid biochemistry and molecular biology, 2022-04, Vol.218, p.106068-106068, Article 106068

2022

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Loss of KMT2C reprograms the epigenomic landscape in hPSCs resulting in NODAL overexpression and a failure of hemogenic endothelium specification

Epigenetics, 2022-02, Vol.17 (2), p.220-238

2022

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Blockade of adipocyte differentiation by cordycepin

British journal of pharmacology, 2012-10, Vol.167 (3), p.561-575

2012

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Creation of Philadelphia chromosome by CRISPR/Cas9-mediated double cleavages on BCR and ABL1 genes as a model for initial event in leukemogenesis

Cancer gene therapy, 2023-01, Vol.30 (1), p.38-50

2023

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IMiDs uniquely synergize with TKIs to upregulate apoptosis of Philadelphia chromosome-positive acute lymphoblastic leukemia cells expressing a dominant-negative IKZF1 isoform

Cell death discovery, 2021-06, Vol.7 (1), p.139-139, Article 139

2021

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Association of relapse-linked ARID5B single nucleotide polymorphisms with drug resistance in B-cell precursor acute lymphoblastic leukemia cell lines

Cancer cell international, 2020-09, Vol.20 (1), p.434-434, Article 434

2020

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Involvement of BCR::ABL1 in laminin adhesion of Philadelphia chromosome‐positive acute lymphoblastic leukemia through upregulation of integrin α6

Cancer reports, 2024-04, Vol.7 (4), p.e2034-n/a

2024

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In utero tumor development and identification of CTNNB1 mutation in a newborn case of ossifying renal tumor of infancy

Pediatric blood & cancer, 2024-04, Vol.71 (4), p.e30868-n/a

2024

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FGFR1 tyrosine kinase domain duplication in infantile soft tissue spindle cell tumor

Pediatric blood & cancer, 2023-09, Vol.70 (9), p.e30354-n/a

2023

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Acquired copy number amplification at the MYC enhancer in human B‐precursor acute lymphoblastic leukemia cell lines

Cancer science, 2024-06

2024

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Application of prime editing system to introduce TP53 R248Q hotspot mutation in acute lymphoblastic leukemia cell line

Cancer science, 2024-06, Vol.115 (6), p.1924-1935

2024

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CRISPR/Cas9-Mediated Induction of Relapse-Specific NT5C2 and PRPS1 Mutations Confers Thiopurine Resistance as a Relapsed Lymphoid Leukemia Model

Molecular pharmacology, 2023-04, Vol.103 (4), p.199-210

2023

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NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells

Journal of cellular and molecular medicine, 2021-11, Vol.25 (22), p.10521-10533

2021

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T315I mutation of BCR-ABL1 into human Philadelphia chromosome-positive leukemia cell lines by homologous recombination using the CRISPR/Cas9 system

Scientific reports, 2018-07, Vol.8 (1), p.9966-12, Article 9966

2018

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Utility of ASNS gene methylation evaluated with the HPLC method as a pharmacogenomic biomarker to predict asparaginase sensitivity in BCP-ALL

Epigenetics, 2023-12, Vol.18 (1), p.2268814-2268814

2023

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Introduction of the T315I gatekeeper mutation of BCR/ABL1 into a Philadelphia chromosome-positive lymphoid leukemia cell line using the CRISPR/Cas9 system

International journal of hematology, 2022-10, Vol.116 (4), p.534-543

2022

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Chemosensitivity is differentially regulated by the SDF-1/CXCR4 and SDF-1/CXCR7 axes in acute lymphoblastic leukemia with MLL gene rearrangements

Leukemia research, 2018-12, Vol.75, p.36-44

2018

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Selective deletion of adipocytes, but not preadipocytes, by TNF-α through C/EBP- and PPARγ-mediated suppression of NF-κB

Laboratory investigation, 2017-02, Vol.97 (2), p.228-228

2017

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TGFβ1 Induces MLL-Rearranged Acute Lymphoblastic Leukemia into Chemoresistant Quiescence in a Coordinated Manner with FLT3 Ligand

Blood, 2016-12, Vol.128 (22), p.3972-3972

2016

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Lenalidomide Effectively Induces Philadelphia-Chromosome Positive ALL Cells into Apoptosis in Synergy with Tyrosine Kinase Inhibitor

Blood, 2016-12, Vol.128 (22), p.1060-1060

2016

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Erratum: Selective deletion of adipocytes, but not preadipocytes, by TNF-α through C/EBP- and PPARγ-mediated suppression of NF-κB

Laboratory investigation, 2017-02, Vol.97 (2), p.228-228

2017

Volltextzugriff (PDF)

Selective deletion of adipocytes, but not preadipocytes, by TNF-[alpha] through C/EBP- and PPAR[gamma]-mediated suppression of NF-[kappa]B

Laboratory investigation, 2017-02, Vol.97 (2), p.228

2017

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Combination of tyrosine kinase inhibitors and the MCL1 inhibitor S63845 exerts synergistic antitumorigenic effects on CML cells

Specific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia

Decreased incidence of acute immune thrombocytopenia in children during the COVID-19 pandemic

Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia

Loss of KMT2C reprograms the epigenomic landscape in hPSCs resulting in NODAL overexpression and a failure of hemogenic endothelium specification

Blockade of adipocyte differentiation by cordycepin

Creation of Philadelphia chromosome by CRISPR/Cas9-mediated double cleavages on BCR and ABL1 genes as a model for initial event in leukemogenesis

IMiDs uniquely synergize with TKIs to upregulate apoptosis of Philadelphia chromosome-positive acute lymphoblastic leukemia cells expressing a dominant-negative IKZF1 isoform

Association of relapse-linked ARID5B single nucleotide polymorphisms with drug resistance in B-cell precursor acute lymphoblastic leukemia cell lines

Involvement of BCR::ABL1 in laminin adhesion of Philadelphia chromosome‐positive acute lymphoblastic leukemia through upregulation of integrin α6

In utero tumor development and identification of CTNNB1 mutation in a newborn case of ossifying renal tumor of infancy

FGFR1 tyrosine kinase domain duplication in infantile soft tissue spindle cell tumor

Acquired copy number amplification at the MYC enhancer in human B‐precursor acute lymphoblastic leukemia cell lines

Application of prime editing system to introduce TP53 R248Q hotspot mutation in acute lymphoblastic leukemia cell line

CRISPR/Cas9-Mediated Induction of Relapse-Specific NT5C2 and PRPS1 Mutations Confers Thiopurine Resistance as a Relapsed Lymphoid Leukemia Model

NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells

T315I mutation of BCR-ABL1 into human Philadelphia chromosome-positive leukemia cell lines by homologous recombination using the CRISPR/Cas9 system

Utility of ASNS gene methylation evaluated with the HPLC method as a pharmacogenomic biomarker to predict asparaginase sensitivity in BCP-ALL

Introduction of the T315I gatekeeper mutation of BCR/ABL1 into a Philadelphia chromosome-positive lymphoid leukemia cell line using the CRISPR/Cas9 system

Chemosensitivity is differentially regulated by the SDF-1/CXCR4 and SDF-1/CXCR7 axes in acute lymphoblastic leukemia with MLL gene rearrangements

Selective deletion of adipocytes, but not preadipocytes, by TNF-α through C/EBP- and PPARγ-mediated suppression of NF-κB

TGFβ1 Induces MLL-Rearranged Acute Lymphoblastic Leukemia into Chemoresistant Quiescence in a Coordinated Manner with FLT3 Ligand

Lenalidomide Effectively Induces Philadelphia-Chromosome Positive ALL Cells into Apoptosis in Synergy with Tyrosine Kinase Inhibitor

Erratum: Selective deletion of adipocytes, but not preadipocytes, by TNF-α through C/EBP- and PPARγ-mediated suppression of NF-κB

Selective deletion of adipocytes, but not preadipocytes, by TNF-[alpha] through C/EBP- and PPAR[gamma]-mediated suppression of NF-[kappa]B

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