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PDGF induces SphK1 expression via Egr-1 to promote pulmonary artery smooth muscle cell proliferation

American Journal of Physiology: Cell Physiology, 2016-06, Vol.310 (11), p.C983-C992

2016

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Micro-RNA-1 is decreased by hypoxia and contributes to the development of pulmonary vascular remodeling via regulation of sphingosine kinase 1

American journal of physiology. Lung cellular and molecular physiology, 2018-03, Vol.314 (3), p.L461-L472

2018

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Hemin Causes Lung Microvascular Endothelial Barrier Dysfunction by Necroptotic Cell Death

American journal of respiratory cell and molecular biology, 2017-09, Vol.57 (3), p.307-314

2017

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The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension

American journal of respiratory and critical care medicine, 2014-11, Vol.190 (9), p.1032-1043

2014

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Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and Is a Therapeutic Target in Pulmonary Arterial Hypertension

Circulation (New York, N.Y.), 2017-04, Vol.135 (16), p.1532-1546

2017

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Training Medical Student Counselors for the Rochester Model, a Hospital Tobacco Treatment Program

Journal of multidisciplinary healthcare, 2024-01, Vol.17, p.601-607

2024

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Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism

Molecular metabolism (Germany), 2016-10, Vol.5 (10), p.926-936

2016

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Targeting proximal tubule mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (33), p.13552-13557

2013

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Sphingosine Kinase 1 Deficiency in Smooth Muscle Cells Protects against Hypoxia-Mediated Pulmonary Hypertension via YAP1 Signaling

International journal of molecular sciences, 2022-11, Vol.23 (23), p.14516

2022

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Genome-Wide Analysis Identifies IL-18 and FUCA2 as Novel Genes Associated with Diastolic Function in African Americans with Sickle Cell Disease

PloS one, 2016-09, Vol.11 (9), p.e0163013

2016

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Cortactin loss protects against hemin-induced acute lung injury in sickle cell disease

American journal of physiology. Lung cellular and molecular physiology, 2022-06, Vol.322 (6), p.L890-L897

2022

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Gene therapy in a murine model of methylmalonic acidemia using rAAV9-mediated gene delivery

Gene therapy, 2012-04, Vol.19 (4), p.385-391

2012

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Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension

American journal of physiology. Lung cellular and molecular physiology, 2015-01, Vol.308 (2), p.L208-L220

2015

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Loss of lung WWOX expression causes neutrophilic inflammation

American journal of physiology. Lung cellular and molecular physiology, 2017-06, Vol.312 (6), p.L903-L911

2017

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Progressive glomerular and tubular damage in sickle cell trait and sickle cell anemia mouse models

Translational research : the journal of laboratory and clinical medicine, 2018-07, Vol.197, p.1-11

2018

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Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria

Nature genetics, 2011-09, Vol.43 (9), p.883-886

2011

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C29 PROTECTORS OF THE LUNG: INNATE IMMUNE RESPONSES IN ACUTE LUNG INJURY: Lung Wwox Knockdown Causes Neutrophilic Inflammation Associated With Increased Epithelial Il-8 Secretion

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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Classification and pathophysiology of pulmonary hypertension

Continuing cardiology education, 2018-06, Vol.4 (1), p.2-12

2018

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B27 HYPOXIA AND THE PULMONARY VASCULATURE: BREATHLESS IN SAN FRANCISCO: Microrna-1 Is Decreased By Hypoxia And Contributes To The Development Of Experimental Pulmonary Hypertension Via Regulation Of Sphingosine Kinase 1 (sphk1)

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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A57 LUNG INJURY, REPAIR, AND FIBROSIS: THE PLOT THICKENS FOR THREE'S COMPANY: Hemin Induces Pulmonary Endothelial Cell Barrier Dysfunction Via Nfkb

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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A54 GENETICS AND EPIGENETIC: Sphingosine Kinase 1 (sphk1) Promoter Is Regulated By Hypoxia And Platelet-Derived Growth Factor (pdgf) In Pulmonary Artery Smooth Muscle Cells

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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A57 LUNG INJURY, REPAIR, AND FIBROSIS: THE PLOT THICKENS FOR THREE'S COMPANY: Mice With Sickle Cell Disease Are Protected From Ventilator-Induced Lung Injury But Not LPS-Induced Lung Injury

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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D43 CELL FATE: Sphingosine-1-Phosphate (s1p) Induces Hypoxia-Inducible Factor-1 Alpha (hif1-[alpha]) Activation In Human Pulmonary Artery Smooth Muscle Cells

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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PDGF induces SphK1 expression via Egr-1 to promote pulmonary artery smooth muscle cell proliferation

Micro-RNA-1 is decreased by hypoxia and contributes to the development of pulmonary vascular remodeling via regulation of sphingosine kinase 1

Hemin Causes Lung Microvascular Endothelial Barrier Dysfunction by Necroptotic Cell Death

The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension

Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and Is a Therapeutic Target in Pulmonary Arterial Hypertension

Training Medical Student Counselors for the Rochester Model, a Hospital Tobacco Treatment Program

Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism

Targeting proximal tubule mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia

Sphingosine Kinase 1 Deficiency in Smooth Muscle Cells Protects against Hypoxia-Mediated Pulmonary Hypertension via YAP1 Signaling

Genome-Wide Analysis Identifies IL-18 and FUCA2 as Novel Genes Associated with Diastolic Function in African Americans with Sickle Cell Disease

Cortactin loss protects against hemin-induced acute lung injury in sickle cell disease

Gene therapy in a murine model of methylmalonic acidemia using rAAV9-mediated gene delivery

Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension

Loss of lung WWOX expression causes neutrophilic inflammation

Progressive glomerular and tubular damage in sickle cell trait and sickle cell anemia mouse models

Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria

C29 PROTECTORS OF THE LUNG: INNATE IMMUNE RESPONSES IN ACUTE LUNG INJURY: Lung Wwox Knockdown Causes Neutrophilic Inflammation Associated With Increased Epithelial Il-8 Secretion

FGF21 underlies a hormetic response to metabolic stress in methylmalonic acidemia

Lipodystrophy in methylmalonic acidemia associated with elevated FGF21 and abnormal methylmalonylation

Classification and pathophysiology of pulmonary hypertension

B27 HYPOXIA AND THE PULMONARY VASCULATURE: BREATHLESS IN SAN FRANCISCO: Microrna-1 Is Decreased By Hypoxia And Contributes To The Development Of Experimental Pulmonary Hypertension Via Regulation Of Sphingosine Kinase 1 (sphk1)

A57 LUNG INJURY, REPAIR, AND FIBROSIS: THE PLOT THICKENS FOR THREE'S COMPANY: Hemin Induces Pulmonary Endothelial Cell Barrier Dysfunction Via Nfkb

A54 GENETICS AND EPIGENETIC: Sphingosine Kinase 1 (sphk1) Promoter Is Regulated By Hypoxia And Platelet-Derived Growth Factor (pdgf) In Pulmonary Artery Smooth Muscle Cells

A57 LUNG INJURY, REPAIR, AND FIBROSIS: THE PLOT THICKENS FOR THREE'S COMPANY: Mice With Sickle Cell Disease Are Protected From Ventilator-Induced Lung Injury But Not LPS-Induced Lung Injury

D43 CELL FATE: Sphingosine-1-Phosphate (s1p) Induces Hypoxia-Inducible Factor-1 Alpha (hif1-[alpha]) Activation In Human Pulmonary Artery Smooth Muscle Cells

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