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High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma

Cancer research (Chicago, Ill.), 2005-12, Vol.65 (23), p.10669-10673

2005

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Diverse somatic mutation patterns and pathway alterations in human cancers

Nature (London), 2010-08, Vol.466 (7308), p.869-873

2010

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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (14), p.5299-5304

2012

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RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

Nature (London), 2010-03, Vol.464 (7287), p.431-435

2010

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Recurrent Loss of NFE2L2 Exon 2 Is a Mechanism for Nrf2 Pathway Activation in Human Cancers

Cell reports (Cambridge), 2016-09, Vol.16 (10), p.2605-2617

2016

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Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis

Molecular & cellular proteomics, 2016-04, Vol.15 (4), p.1220-1231

2016

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Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes

Cancer research (Chicago, Ill.), 2016-04, Vol.76 (7), p.1975-1988

2016

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Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes

Cancer research (Chicago, Ill.), 2014-06, Vol.74 (11), p.3114-3126

2014

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Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma

Nature medicine, 2007-01, Vol.13 (1), p.84-88

2007

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Bioelectrical impedance vector analysis, phase-angle assessment and relationship with malnutrition risk in a cohort of frail older hospital patients in the United Kingdom

Nutrition (Burbank, Los Angeles County, Calif.), 2015, Vol.31 (1), p.132-137

2015

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Zinc finger nucleases as tools to understand and treat human diseases

BMC medicine, 2010-07, Vol.8 (1), p.42-42, Article 42

2010

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Molecular Determinants of the Response of Glioblastomas to EGFR Kinase Inhibitors

The New England journal of medicine, 2005-11, Vol.353 (19), p.2012-2024

2005

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Structure of the p53 degradation complex from HPV16

Nature communications, 2024-02, Vol.15 (1), p.1842-1842, Article 1842

2024

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Epidermal Growth Factor Receptor, Protein Kinase B/Akt, and Glioma Response to Erlotinib

JNCI : Journal of the National Cancer Institute, 2005-06, Vol.97 (12), p.880-887

2005

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Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Journal of clinical oncology, 2009-02, Vol.27 (4), p.579-584

2009

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A CRISPR screen identifies MAPK7 as a target for combination with MEK inhibition in KRAS mutant NSCLC

PloS one, 2018-06, Vol.13 (6), p.e0199264-e0199264

2018

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ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung Cancer

Cancer research (Chicago, Ill.), 2019-10, Vol.79 (19), p.4828-4839

2019

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Disruption of PH–kinase domain interactions leads to oncogenic activation of AKT in human cancers

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (47), p.19368-19373

2012

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A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle

Current biology, 2002-06, Vol.12 (11), p.919-924

2002

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Genetic Alterations and Oncogenic Pathways Associated with Breast Cancer Subtypes

Molecular cancer research, 2009-04, Vol.7 (4), p.511-522

2009

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EGFR signals to mTOR through PKC and independently of Akt in glioma

Science signaling, 2009-01, Vol.2 (55), p.ra4

2009

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The relationship between malnutrition risk and clinical outcomes in a cohort of frail older hospital patients

Clinical nutrition ESPEN, 2016-10, Vol.15, p.57-62

2016

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A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition

Biochemical journal, 2008-10, Vol.415 (1), p.97-110

2008

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New insights into PTEN

Journal of cell science, 2007-12, Vol.120 (23), p.4071-4079

2007

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High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma

Diverse somatic mutation patterns and pathway alterations in human cancers

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

Recurrent Loss of NFE2L2 Exon 2 Is a Mechanism for Nrf2 Pathway Activation in Human Cancers

Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis

Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes

Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes

Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma

Bioelectrical impedance vector analysis, phase-angle assessment and relationship with malnutrition risk in a cohort of frail older hospital patients in the United Kingdom

Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events

Zinc finger nucleases as tools to understand and treat human diseases

Molecular Determinants of the Response of Glioblastomas to EGFR Kinase Inhibitors

Structure of the p53 degradation complex from HPV16

Epidermal Growth Factor Receptor, Protein Kinase B/Akt, and Glioma Response to Erlotinib

Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

A CRISPR screen identifies MAPK7 as a target for combination with MEK inhibition in KRAS mutant NSCLC

ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung Cancer

Disruption of PH–kinase domain interactions leads to oncogenic activation of AKT in human cancers

A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle

Genetic Alterations and Oncogenic Pathways Associated with Breast Cancer Subtypes

EGFR signals to mTOR through PKC and independently of Akt in glioma

The relationship between malnutrition risk and clinical outcomes in a cohort of frail older hospital patients

A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition

New insights into PTEN

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