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Insulin-Sensitive Protein Kinases (Atypical Protein Kinase C and Protein Kinase B/Akt): Actions and Defects in Obesity and Type II Diabetes

Experimental biology and medicine (Maywood, N.J.), 2005-10, Vol.230 (9), p.593-605

2005

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Design, manufacturing and validation of a vertical-axis wind turbine setup for wind tunnel tests

Journal of wind engineering and industrial aerodynamics, 2019-10, Vol.193, p.103949, Article 103949

2019

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AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC

American journal of physiology: endocrinology and metabolism, 2010-02, Vol.298 (2), p.E179-E192

2010

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Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFκB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance

Diabetologia, 2009-06, Vol.52 (6), p.1197-1207

2009

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Design study of a 17.3 GHz electron cyclotron resonance (ECR) ion source at Louvain-la-Neuve

Review of scientific instruments, 2014-02, Vol.85 (2)

2014

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The critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFκB in obesity

Journal of lipid research, 2009-06, Vol.50 (6), p.1133-1145

2009

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Insulin and PIP3 Activate PKC-ζ by Mechanisms That Are Both Dependent and Independent of Phosphorylation of Activation Loop (T410) and Autophosphorylation (T560) Sites

Biochemistry (Easton), 2001-01, Vol.40 (1), p.249-255

2001

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Repletion of Atypical Protein Kinase C following RNA Interference-mediated Depletion Restores Insulin-stimulated Glucose Transport

The Journal of biological chemistry, 2006-06, Vol.281 (25), p.17466-17473

2006

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Metformin improves atypical protein kinase C activation by insulin and phosphatidylinositol-3,4,5-(PO₄)₃ in muscle of diabetic subjects

Diabetologia, 2006-02, Vol.49 (2), p.375-382

2006

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Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport

The Journal of biological chemistry, 1997-11, Vol.272 (48), p.30075

1997

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P185 – 2567: Problems in orientation and mobility in children with CVI

European journal of paediatric neurology, 2015-05, Vol.19, p.S146-S146

2015

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Atypical protein kinase C in insulin action and insulin resistance

Biochemical Society transactions, 2005-04, Vol.33 (Pt 2), p.350-353

2005

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Insulin signaling and insulin sensitizing in muscle and liver of obese monkeys: peroxisome proliferator-activated receptor gamma agonist improves defective activation of atypical protein kinase C

Antioxidants & redox signaling, 2011-01, Vol.14 (2), p.207-219

2011

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Chronic activation of protein kinase C in soleus muscles and other tissues of insulin-resistant type II diabetic Goto-Kakizaki (GK), obese/aged, and obese/Zucker rats. A mechanism for inhibiting glycogen synthesis

Diabetes (New York, N.Y.), 1996-10, Vol.45 (10), p.1396-1404

1996

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Skeletal Muscle Insulin Resistance in Obesity-Associated Type 2 Diabetes in Monkeys Is Linked to a Defect in Insulin Activation of Protein Kinase C-ζ/λ/ι

Diabetes (New York, N.Y.), 2002-10, Vol.51 (10), p.2936-2943

2002

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Protein Kinase C-λ Knockout in Embryonic Stem Cells and Adipocytes Impairs Insulin-Stimulated Glucose Transport

Molecular endocrinology (Baltimore, Md.), 2004-02, Vol.18 (2), p.373-383

2004

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Insulin Activates Protein Kinases C-ζ and C-λ by an Autophosphorylation-dependent Mechanism and Stimulates Their Translocation to GLUT4 Vesicles and Other Membrane Fractions in Rat Adipocytes

The Journal of biological chemistry, 1999-09, Vol.274 (36), p.25308-25316

1999

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Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states

The Journal of biological chemistry, 2004-06, Vol.279 (24), p.24929-24934

2004

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Akt-Dependent Phosphorylation of Hepatic FoxO1 Is Compartmentalized on a WD40/ProF Scaffold and Is Selectively Inhibited by aPKC in Early Phases of Diet-Induced Obesity

Diabetes (New York, N.Y.), 2014-08, Vol.63 (8), p.2690-2701

2014

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Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport

The Journal of biological chemistry, 1997-01, Vol.272 (4), p.2551

1997

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Combined thiazolidinedione-metformin treatment synergistically improves insulin signalling to insulin receptor substrate-1-dependent phosphatidylinositol 3-kinase, atypical protein kinase C and protein kinase B/Akt in human diabetic muscle

Diabetologia, 2009-01, Vol.52 (1), p.60-64

2009

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Effects of transiently expressed atypical (zeta, lambda), conventional (alpha, beta) and novel (delta, epsilon) protein kinase C isoforms on insulin-stimulated translocation of epitope-tagged GLUT4 glucose transporters in rat adipocytes: specific interchangeable effects of protein kinases C-zeta and C-lambda

Biochemical journal, 1999-02, Vol.337 ( Pt 3) (3), p.461-470

1999

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Increased atypical PKC activity in endurance-trained human skeletal muscle

Biochemical and biophysical research communications, 2003-12, Vol.312 (4), p.1147-1153

2003

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Insulin Substrates 1 and 2 Are Corequired for Activation of Atypical Protein Kinase C and Cbl-Dependent Phosphatidylinositol 3-Kinase during Insulin Action in Immortalized Brown Adipocytes

Biochemistry (Easton), 2004-12, Vol.43 (49), p.15503-15509

2004

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Glucose Activates Mitogen-activated Protein Kinase (Extracellular Signal-regulated Kinase) through Proline-rich Tyrosine Kinase-2 and the Glut1 Glucose Transporter

The Journal of biological chemistry, 2000-12, Vol.275 (52), p.40817-40826

2000

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Insulin-Sensitive Protein Kinases (Atypical Protein Kinase C and Protein Kinase B/Akt): Actions and Defects in Obesity and Type II Diabetes

Design, manufacturing and validation of a vertical-axis wind turbine setup for wind tunnel tests

AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC

Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFκB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance

Design study of a 17.3 GHz electron cyclotron resonance (ECR) ion source at Louvain-la-Neuve

The critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFκB in obesity

Insulin and PIP3 Activate PKC-ζ by Mechanisms That Are Both Dependent and Independent of Phosphorylation of Activation Loop (T410) and Autophosphorylation (T560) Sites

Repletion of Atypical Protein Kinase C following RNA Interference-mediated Depletion Restores Insulin-stimulated Glucose Transport

Metformin improves atypical protein kinase C activation by insulin and phosphatidylinositol-3,4,5-(PO₄)₃ in muscle of diabetic subjects

Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport

P185 – 2567: Problems in orientation and mobility in children with CVI

Atypical protein kinase C in insulin action and insulin resistance

Insulin signaling and insulin sensitizing in muscle and liver of obese monkeys: peroxisome proliferator-activated receptor gamma agonist improves defective activation of atypical protein kinase C

Chronic activation of protein kinase C in soleus muscles and other tissues of insulin-resistant type II diabetic Goto-Kakizaki (GK), obese/aged, and obese/Zucker rats. A mechanism for inhibiting glycogen synthesis

Skeletal Muscle Insulin Resistance in Obesity-Associated Type 2 Diabetes in Monkeys Is Linked to a Defect in Insulin Activation of Protein Kinase C-ζ/λ/ι

Protein Kinase C-λ Knockout in Embryonic Stem Cells and Adipocytes Impairs Insulin-Stimulated Glucose Transport

Insulin Activates Protein Kinases C-ζ and C-λ by an Autophosphorylation-dependent Mechanism and Stimulates Their Translocation to GLUT4 Vesicles and Other Membrane Fractions in Rat Adipocytes

Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states

Akt-Dependent Phosphorylation of Hepatic FoxO1 Is Compartmentalized on a WD40/ProF Scaffold and Is Selectively Inhibited by aPKC in Early Phases of Diet-Induced Obesity

Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport

Combined thiazolidinedione-metformin treatment synergistically improves insulin signalling to insulin receptor substrate-1-dependent phosphatidylinositol 3-kinase, atypical protein kinase C and protein kinase B/Akt in human diabetic muscle

Increased atypical PKC activity in endurance-trained human skeletal muscle

Insulin Substrates 1 and 2 Are Corequired for Activation of Atypical Protein Kinase C and Cbl-Dependent Phosphatidylinositol 3-Kinase during Insulin Action in Immortalized Brown Adipocytes

Glucose Activates Mitogen-activated Protein Kinase (Extracellular Signal-regulated Kinase) through Proline-rich Tyrosine Kinase-2 and the Glut1 Glucose Transporter

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