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A BMP7 variant inhibits the tumorigenic potential of glioblastoma stem-like cells

Cell death and differentiation, 2012-10, Vol.19 (10), p.1644-1654

2012

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Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo

Cell death & disease, 2014-05, Vol.5 (5), p.e1223-e1223

2014

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Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F

Blood cancer journal (New York), 2013-04, Vol.3 (4), p.e109-e109

2013

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404 LY2228820 Dimesylate, a P38 MAPK Inhibitor, Demonstrates Anti-Neoplastic Activity in Mouse Models of Human Ovarian Cancer

European journal of cancer (1990), 2012-11, Vol.48, p.123-123

2012

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Importance of the MKK6/p38 pathway for interleukin-12–induced STAT4 serine phosphorylation and transcriptional activity

Blood, 2000-09, Vol.96 (5), p.1844-1852

2000

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Antiproliferative action of interferon-α requires components of T-cell-receptor signalling

Nature (London), 1997-12, Vol.390 (6660), p.629-632

1997

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Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system

The Journal of biological chemistry, 1993-10, Vol.268 (29), p.21711-21716

1993

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Characterization of LY2228820 dimesylate, a potent and selective inhibitor of p38 MAPK with antitumor activity

Molecular cancer therapeutics, 2014-02, Vol.13 (2), p.364-374

2014

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Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway

Molecular and Cellular Biology, 1997-07, Vol.17 (7), p.3833-3840

1997

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The hsp90-binding Antibiotic Geldanamycin Decreases Raf Levels and Epidermal Growth Factor Signaling without Disrupting Formation of Signaling Complexes or Reducing the Specific Enzymatic Activity of Raf Kinase

The Journal of biological chemistry, 1997-02, Vol.272 (7), p.4013-4020

1997

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Fingerprinting of signal transduction pathways using a combination of anti-phosphotyrosine immunoprecipitations and two-dimensional polyacrylamide gel electrophoresis

Electrophoresis, 2001-06, Vol.22 (10), p.2120-2124

2001

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The 23-kDa Acidic Protein in Reticulocyte Lysate Is the Weakly Bound Component of the hsp Foldosome That Is Required for Assembly of the Glucocorticoid Receptor into a Functional Heterocomplex with hsp90 (∗)

The Journal of biological chemistry, 1995-08, Vol.270 (32), p.18841-18847

1995

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Binding of Immunophilins to the 90 kDa Heat Shock Protein (hsp90) via a Tetratricopeptide Repeat Domain Is a Conserved Protein Interaction in Plants

Biochemistry (Easton), 1996-12, Vol.35 (48), p.15249-15255

1996

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The hsp56 immunophilin component of steroid receptor heterocomplexes: Could this be the elusive nuclear localization signal-binding protein?

Journal of Steroid Biochemistry and Molecular Biology, 1993-09, Vol.46 (3), p.269-279

1993

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Animal and Plant Cell Lysates Share a Conserved Chaperone System That Assembles the Glucocorticoid Receptor into a Functional Heterocomplex with hsp90

Biochemistry (Easton), 1996-01, Vol.35 (2), p.554-561

1996

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Association of a p95 Vav-containing signaling complex with the Fc epsilon RI gamma chain in the RBL-2H3 mast cell line. Evidence for a constitutive in vivo association of Vav with Grb2, Raf-1, and ERK2 in an active complex

The Journal of biological chemistry, 1996, Vol.271 (43), p.26962-26970

1996

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Role of PRL-3, a Human Muscle-Specific Tyrosine Phosphatase, in Angiotensin-II Signaling

Biochemical and biophysical research communications, 2001-05, Vol.283 (5), p.1061-1068

2001

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Ability of various members of the hsp70 family of chaperones to promote assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90

The Journal of steroid biochemistry and molecular biology, 1996-06, Vol.58 (3), p.251-258

1996

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Activation of Raf-1 by interferon gamma and oncostatin M requires expression of the Stat1 transcription factor

The Journal of biological chemistry, 1998-07, Vol.273 (30), p.18701-18704

1998

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Use of the thiol-specific derivatizing agent N-iodoacetyl-3-[125I]iodotyrosine to demonstrate conformational differences between the unbound and hsp90-bound glucocorticoid receptor hormone binding domain

The Journal of biological chemistry, 1996-04, Vol.271 (15), p.8831-8836

1996

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Heat stress protects the perfused rabbit heart from complement-mediated injury

American journal of physiology. Heart and circulatory physiology, 1996-08, Vol.271 (2), p.H571-H578

1996

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Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis

Mechanisms of development, 2000-03, Vol.91 (1), p.97-104

2000

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Preassociation of STAT1 with STAT2 and STAT3 in Separate Signalling Complexes Prior to Cytokine Stimulation (∗)

The Journal of biological chemistry, 1996-02, Vol.271 (8), p.4134-4137

1996

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Differential effects of the reversible thiol-reactive agents arsenite and methyl methanethiosulfonate on steroid binding by the glucocorticoid receptor

Biochemistry (Easton), 1993-04, Vol.32 (14), p.3729-3736

1993

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Regulation of Glucocorticoid Receptor Function through Assembly of a Receptor-Heat Shock Protein Complex

Annals of the New York Academy of Sciences, 1993-06, Vol.684 (1), p.35-48

1993

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A BMP7 variant inhibits the tumorigenic potential of glioblastoma stem-like cells

Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo

Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F

404 LY2228820 Dimesylate, a P38 MAPK Inhibitor, Demonstrates Anti-Neoplastic Activity in Mouse Models of Human Ovarian Cancer

Importance of the MKK6/p38 pathway for interleukin-12–induced STAT4 serine phosphorylation and transcriptional activity

Antiproliferative action of interferon-α requires components of T-cell-receptor signalling

Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system

Characterization of LY2228820 dimesylate, a potent and selective inhibitor of p38 MAPK with antitumor activity

Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway

The hsp90-binding Antibiotic Geldanamycin Decreases Raf Levels and Epidermal Growth Factor Signaling without Disrupting Formation of Signaling Complexes or Reducing the Specific Enzymatic Activity of Raf Kinase

Fingerprinting of signal transduction pathways using a combination of anti-phosphotyrosine immunoprecipitations and two-dimensional polyacrylamide gel electrophoresis

The 23-kDa Acidic Protein in Reticulocyte Lysate Is the Weakly Bound Component of the hsp Foldosome That Is Required for Assembly of the Glucocorticoid Receptor into a Functional Heterocomplex with hsp90 (∗)

Binding of Immunophilins to the 90 kDa Heat Shock Protein (hsp90) via a Tetratricopeptide Repeat Domain Is a Conserved Protein Interaction in Plants

The hsp56 immunophilin component of steroid receptor heterocomplexes: Could this be the elusive nuclear localization signal-binding protein?

Animal and Plant Cell Lysates Share a Conserved Chaperone System That Assembles the Glucocorticoid Receptor into a Functional Heterocomplex with hsp90

Association of a p95 Vav-containing signaling complex with the Fc epsilon RI gamma chain in the RBL-2H3 mast cell line. Evidence for a constitutive in vivo association of Vav with Grb2, Raf-1, and ERK2 in an active complex

Role of PRL-3, a Human Muscle-Specific Tyrosine Phosphatase, in Angiotensin-II Signaling

Ability of various members of the hsp70 family of chaperones to promote assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90

Activation of Raf-1 by interferon gamma and oncostatin M requires expression of the Stat1 transcription factor

Use of the thiol-specific derivatizing agent N-iodoacetyl-3-[125I]iodotyrosine to demonstrate conformational differences between the unbound and hsp90-bound glucocorticoid receptor hormone binding domain

Heat stress protects the perfused rabbit heart from complement-mediated injury

Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis

Preassociation of STAT1 with STAT2 and STAT3 in Separate Signalling Complexes Prior to Cytokine Stimulation (∗)

Differential effects of the reversible thiol-reactive agents arsenite and methyl methanethiosulfonate on steroid binding by the glucocorticoid receptor

Regulation of Glucocorticoid Receptor Function through Assembly of a Receptor-Heat Shock Protein Complex

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