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A time course analysis of the electrophysiological properties of neurons differentiated from human induced pluripotent stem cells (iPSCs)

PloS one, 2014-07, Vol.9 (7), p.e103418-e103418

2014

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Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9

Nature (London), 2016-05, Vol.533 (7601), p.125-129

2016

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Alzheimer’s disease and the autophagic-lysosomal system

Neuroscience letters, 2019-04, Vol.697, p.49-58

2019

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Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors

PloS one, 2014-01, Vol.9 (1), p.e84547-e84547

2014

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The Alzheimer's disease‐associated C99 fragment of APP regulates cellular cholesterol trafficking

The EMBO journal, 2020-10, Vol.39 (20), p.e103791-n/a

2020

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Being human: The role of pluripotent stem cells in regenerative medicine and humanizing Alzheimer's disease models

Molecular aspects of medicine, 2015-06, Vol.43-44, p.54-65

Sproul, Andrew A.

2015

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Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer's Disease-Associated Presenilin 1 Mutation

Frontiers in molecular neuroscience, 2017-09, Vol.10, p.291-291

2017

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CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage

Nature communications, 2019-01, Vol.10 (1), p.53-11, Article 53

2019

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Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate

Proceedings of the National Academy of Sciences - PNAS, 2021-02, Vol.118 (8), p.1

2021

Volltextzugriff (PDF)

Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy

Nature communications, 2022-08, Vol.13 (1), p.4444-4444, Article 4444

2022

Volltextzugriff (PDF)

Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics

Cell death & disease, 2022-11, Vol.13 (11), p.959-959, Article 959

2022

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Improved methods for reprogramming human dermal fibroblasts using fluorescence activated cell sorting

PloS one, 2013-03, Vol.8 (3), p.e59867

2013

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RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation

Acta neuropathologica, 2023-01, Vol.145 (1), p.29-48

2023

Volltextzugriff (PDF)

Xenografted human iPSC-derived neurons with the familial Alzheimer’s disease APPV717I mutation reveal dysregulated transcriptome signatures linked to synaptic function and implicate LINGO2 as a disease signaling mediator

Acta neuropathologica, 2024-06, Vol.147 (1), p.107, Article 107

2024

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ZCCHC17 Modulates Neuronal RNA Splicing and Supports Cognitive Resilience in Alzheimer's Disease

The Journal of neuroscience, 2024-01, Vol.44 (3), p.e2324222023

2024

Volltextzugriff (PDF)

Pro-apoptotic Bim Induction in Response to Nerve Growth Factor Deprivation Requires Simultaneous Activation of Three Different Death Signaling Pathways

The Journal of biological chemistry, 2007-10, Vol.282 (40), p.29368-29374

2007

Volltextzugriff (PDF)

Characterization of a subpopulation of developing cortical interneurons from human iPSCs within serum-free embryoid bodies

American Journal of Physiology: Cell Physiology, 2015-02, Vol.308 (3), p.C209-C219

2015

Volltextzugriff (PDF)

Crosstalk between acetylation and the tyrosination/detyrosination cycle of α-tubulin in Alzheimer’s disease

Frontiers in cell and developmental biology, 2022-08, Vol.10, p.926914-926914

2022

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Differentiation of serum-free embryoid bodies from human induced pluripotent stem cells into networks

Stem cell research, 2013-05, Vol.10 (3), p.454-463

2013

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Sh3rf2/POSHER Protein Promotes Cell Survival by Ring-mediated Proteasomal Degradation of the c-Jun N-terminal Kinase Scaffold POSH (Plenty of SH3s) Protein

The Journal of biological chemistry, 2012-01, Vol.287 (3), p.2247-2256

2012

Volltextzugriff (PDF)

Siah1 Interacts with the Scaffold Protein POSH to Promote JNK Activation and Apoptosis

The Journal of biological chemistry, 2006-01, Vol.281 (1), p.303-312

2006

Volltextzugriff (PDF)

Generation of iPSC lines from archived non-cryoprotected biobanked dura mater

Acta neuropathologica communications, 2014-01, Vol.2 (1), p.4-4, Article 4

2014

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Cbl negatively regulates JNK activation and cell death

Cell research, 2009-08, Vol.19 (8), p.950-961

2009

Volltextzugriff (PDF)

Impaired Microtubule Dynamics Are a Driver of Tau Phosphorylation

Alzheimer's & dementia, 2023-12, Vol.19 (S13), p.n/a

2023

Volltextzugriff (PDF)

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A time course analysis of the electrophysiological properties of neurons differentiated from human induced pluripotent stem cells (iPSCs)

Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9

Alzheimer’s disease and the autophagic-lysosomal system

Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors

The Alzheimer's disease‐associated C99 fragment of APP regulates cellular cholesterol trafficking

Being human: The role of pluripotent stem cells in regenerative medicine and humanizing Alzheimer's disease models

Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer's Disease-Associated Presenilin 1 Mutation

CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage

Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate

Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy

Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics

Improved methods for reprogramming human dermal fibroblasts using fluorescence activated cell sorting

RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation

Xenografted human iPSC-derived neurons with the familial Alzheimer’s disease APPV717I mutation reveal dysregulated transcriptome signatures linked to synaptic function and implicate LINGO2 as a disease signaling mediator

ZCCHC17 Modulates Neuronal RNA Splicing and Supports Cognitive Resilience in Alzheimer's Disease

Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons

Pro-apoptotic Bim Induction in Response to Nerve Growth Factor Deprivation Requires Simultaneous Activation of Three Different Death Signaling Pathways

Characterization of a subpopulation of developing cortical interneurons from human iPSCs within serum-free embryoid bodies

Crosstalk between acetylation and the tyrosination/detyrosination cycle of α-tubulin in Alzheimer’s disease

Differentiation of serum-free embryoid bodies from human induced pluripotent stem cells into networks

Sh3rf2/POSHER Protein Promotes Cell Survival by Ring-mediated Proteasomal Degradation of the c-Jun N-terminal Kinase Scaffold POSH (Plenty of SH3s) Protein

Siah1 Interacts with the Scaffold Protein POSH to Promote JNK Activation and Apoptosis

Generation of iPSC lines from archived non-cryoprotected biobanked dura mater

Cbl negatively regulates JNK activation and cell death

Impaired Microtubule Dynamics Are a Driver of Tau Phosphorylation

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