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Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain

PLoS biology, 2017-07, Vol.15 (7), p.e2002457-e2002457

2017

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A phase 1, randomized, placebo-controlled study to evaluate the safety and immunogenicity of an mRNA-based RSV prefusion F protein vaccine in healthy younger and older adults

Human vaccines & immunotherapeutics, 2021-05, Vol.17 (5), p.1248-1261

2021

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Validation of a multiplexed and targeted lipidomics assay for accurate quantification of lipidomes

Journal of lipid research, 2022-06, Vol.63 (6), p.100218-100218, Article 100218

2022

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Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac

Science signaling, 2011-12, Vol.4 (202), p.ra82

2011

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Investigating Performance of the SLIM-Based High Resolution Ion Mobility Platform for Separation of Isomeric Phosphatidylcholine Species

Journal of the American Society for Mass Spectrometry, 2023-10, Vol.34 (10), p.2176-2186

2023

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Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

Clinical pharmacology and therapeutics, 2019-09, Vol.106 (3), p.525-543

2019

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Intact Mass Quantitation of Therapeutic Antibodies for Pharmacokinetic Studies Using Immuno-Purification

Methods in molecular biology (Clifton, N.J.), 2022, Vol.2313, p.259

2022

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Quantification of tau in cerebrospinal fluid by immunoaffinity enrichment and tandem mass spectrometry

Clinical chemistry (Baltimore, Md.), 2014-04, Vol.60 (4), p.683-689

2014

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Generic Automated Method for Liquid Chromatography–Multiple Reaction Monitoring Mass Spectrometry Based Monoclonal Antibody Quantitation for Preclinical Pharmacokinetic Studies

Analytical chemistry (Washington), 2014-09, Vol.86 (17), p.8776-8784

2014

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Improving the throughput of immunoaffinity purification and enzymatic digestion of therapeutic proteins using membrane-immobilized reagent technology

Analyst (London), 2020-04, Vol.145 (8), p.3148-3156

2020

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Development and evaluation of a multiplexed mass spectrometry based assay for measuring candidate peptide biomarkers in Alzheimer's Disease Neuroimaging Initiative (ADNI) CSF

Proteomics. Clinical applications, 2015-08, Vol.9 (7-8), p.715-731

2015

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Direct quantitation of therapeutic antibodies for pharmacokinetic studies using immuno-purification and intact mass analysis

Bioanalysis, 2019-02, Vol.11 (3), p.203-213

2019

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Quantitation of a Therapeutic Antibody in Serum Using Intact Sequential Affinity Capture, Trypsin Digestion, and LC-MS/MS

Analytical chemistry (Washington), 2018-01, Vol.90 (1), p.866-871

2018

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Proteomic Discovery and Validation of Novel Fluid Biomarkers for Improved Patient Selection and Prediction of Clinical Outcomes in Alzheimer’s Disease Patient Cohorts

Proteomes, 2022-08, Vol.10 (3), p.26

2022

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Longitudinal CSF proteomics identifies NPTX2 as a prognostic biomarker of Alzheimer's disease

Alzheimer's & dementia, 2021-12, Vol.17 (12), p.1976-1987

2021

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Correction: Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain

PLoS biology, 2021-11, Vol.19 (11), p.e3001452-e3001452

2021

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Evaluation of a stabilized RSV pre-fusion F mRNA vaccine: Preclinical studies and Phase 1 clinical testing in healthy adults

Vaccine, 2023-10, Vol.41 (44), p.6488-6501

2023

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Quantitative analysis of intact apolipoproteins in human HDL by top-down differential mass spectrometry

Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (17), p.7728-7733

2010

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Forward and reverse translational approaches to predict efficacy of neutralizing respiratory syncytial virus (RSV) antibody prophylaxis

EBioMedicine, 2021-11, Vol.73, p.103651-103651, Article 103651

2021

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Stable isotopic labeling by amino acids in cultured primary neurons: application to brain-derived neurotrophic factor-dependent phosphotyrosine-associated signaling

Molecular & cellular proteomics, 2008-06, Vol.7 (6), p.1067-1076

2008

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Mass Spectrometry-Based Biomarkers in Drug Development

Advancements of Mass Spectrometry in Biomedical Research, 2019, Vol.1140, p.435-449

2019

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Quantitation of human peptides and proteins via MS: review of analytically validated assays

Bioanalysis, 2014-01, Vol.6 (13), p.1843-1857

2014

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Stable Isotopic Labeling by Amino Acids in Cultured Primary Neurons

Molecular & cellular proteomics, 2008-06, Vol.7 (6), p.1067-1076

2008

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Automated DBS microsampling, microscale automation and microflow LC-MS for therapeutic protein PK

Bioanalysis, 2016-04, Vol.8 (7), p.649-659

2016

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Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain

A phase 1, randomized, placebo-controlled study to evaluate the safety and immunogenicity of an mRNA-based RSV prefusion F protein vaccine in healthy younger and older adults

Validation of a multiplexed and targeted lipidomics assay for accurate quantification of lipidomes

Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac

Investigating Performance of the SLIM-Based High Resolution Ion Mobility Platform for Separation of Isomeric Phosphatidylcholine Species

Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

Intact Mass Quantitation of Therapeutic Antibodies for Pharmacokinetic Studies Using Immuno-Purification

Quantification of tau in cerebrospinal fluid by immunoaffinity enrichment and tandem mass spectrometry

Generic Automated Method for Liquid Chromatography–Multiple Reaction Monitoring Mass Spectrometry Based Monoclonal Antibody Quantitation for Preclinical Pharmacokinetic Studies

Improving the throughput of immunoaffinity purification and enzymatic digestion of therapeutic proteins using membrane-immobilized reagent technology

Development and evaluation of a multiplexed mass spectrometry based assay for measuring candidate peptide biomarkers in Alzheimer's Disease Neuroimaging Initiative (ADNI) CSF

Direct quantitation of therapeutic antibodies for pharmacokinetic studies using immuno-purification and intact mass analysis

Quantitation of a Therapeutic Antibody in Serum Using Intact Sequential Affinity Capture, Trypsin Digestion, and LC-MS/MS

Proteomic Discovery and Validation of Novel Fluid Biomarkers for Improved Patient Selection and Prediction of Clinical Outcomes in Alzheimer’s Disease Patient Cohorts

Longitudinal CSF proteomics identifies NPTX2 as a prognostic biomarker of Alzheimer's disease

Correction: Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain

Evaluation of a stabilized RSV pre-fusion F mRNA vaccine: Preclinical studies and Phase 1 clinical testing in healthy adults

Quantitative analysis of intact apolipoproteins in human HDL by top-down differential mass spectrometry

The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer

Forward and reverse translational approaches to predict efficacy of neutralizing respiratory syncytial virus (RSV) antibody prophylaxis

Stable isotopic labeling by amino acids in cultured primary neurons: application to brain-derived neurotrophic factor-dependent phosphotyrosine-associated signaling

Mass Spectrometry-Based Biomarkers in Drug Development

Quantitation of human peptides and proteins via MS: review of analytically validated assays

Stable Isotopic Labeling by Amino Acids in Cultured Primary Neurons

Automated DBS microsampling, microscale automation and microflow LC-MS for therapeutic protein PK

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