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New drugs and emerging therapeutic targets in the endothelin signaling pathway and prospects for personalized precision medicine

Physiological research, 2018-01, Vol.67 (Suppl 1), p.S37-S54

2018

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Exploiting new genome data and Internet resources for the phylogenetic analysis of proteases, substrates and inhibitors

Biochemical Society transactions, 2007-06, Vol.35 (Pt 3), p.599-603

Southan, C

2007

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Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

Molecular and cellular neuroscience, 1999-12, Vol.14 (6), p.419-427

1999

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Has the yo-yo stopped? An assessment of human protein-coding gene number

Proteomics (Weinheim), 2004-06, Vol.4 (6), p.1712-1726

Southan, Christopher

2004

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The HtrA Family of Proteases: Implications for Protein Composition and Cell Fate

Molecular Cell, 2002-09, Vol.10 (3), p.443-455

2002

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ASP1 (BACE2) Cleaves the Amyloid Precursor Protein at the β-Secretase Site

Molecular and cellular neuroscience, 2000-11, Vol.16 (5), p.609-619

2000

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Extracting and connecting chemical structures from text sources using chemicalize.org

Journal of cheminformatics, 2013-04, Vol.5 (1), p.20-20, Article 20

2013

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A genomic perspective on human proteases as drug targets

Drug Discovery Today, 2001-07, Vol.6 (13), p.681-688

Southan, Christopher

2001

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A genomic perspective on human proteases

FEBS Letters, 2001-06, Vol.498 (2), p.214-218

Southan, Christopher

2001

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The Concise Guide to PHARMACOLOGY 2015/16: Other ion channels

British journal of pharmacology, 2015-12, Vol.172 (24), p.5942-5955

2015

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Assessing the protease and protease inhibitor content of the human genome

Journal of peptide science, 2000-09, Vol.6 (9), p.453-458

Southan, Christopher

2000

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Splice variants: A homology modeling approach

Proteins, structure, function, and bioinformatics, 2004-02, Vol.54 (3), p.596-608

2004

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Rat ATP citrate-lyase. Molecular cloning and sequence analysis of a full-length cDNA and mRNA abundance as a function of diet, organ, and age

The Journal of biological chemistry, 1990-01, Vol.265 (3), p.1430-1435

1990

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The separation of glutathione transferase subunits by using reverse-phase high-pressure liquid chromatography

Biochemical journal, 1987-07, Vol.245 (2), p.423-428

1987

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Website review: interPro (the integrated resource of protein domains and functional sites)

Yeast (Chichester, England), 2000-12, Vol.17 (4), p.327-334

Southan, C

2000

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The glutathione transferase activity and tissue distribution of a cloned Mr28K protective antigen of Schistosoma mansoni

The EMBO journal, 1988-02, Vol.7 (2), p.465-472

1988

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Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

European journal of biochemistry, 2000-09, Vol.267 (18), p.5699-5710

2000

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Purification, properties, sequencing, and cloning of a lipoprotein-associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoproteins

Arteriosclerosis, thrombosis, and vascular biology, 1996-04, Vol.16 (4), p.591-599

1996

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Towards BioDBcore: a community-defined information specification for biological databases

Database : the journal of biological databases and curation, 2011-01, Vol.2011, p.baq027-baq027

2011

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3.19 - Examples of SAR-Centric Patent Mining Using Open Resources

Comprehensive Medicinal Chemistry III, 2017, p.464-487

Southan, C.

Third Edition, 2017

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The analysis of fibrinopeptide release from S--carboxymethylated fibrinogen chains using high-performance liquid chromatography

Structural variants and interactions, 2019, Vol.3, p.73-82

Originally published 1985, 2019

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Identification, Genomic Organization, and mRNA Expression of LACTB, Encoding a Serine β-Lactamase-like Protein with an Amino-terminal Transmembrane Domain

Genomics (San Diego, Calif.), 2001-11, Vol.78 (1-2), p.12-14

2001

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Characterization of peptides cleaved by plasmin from the C-terminal polymerization domain of human fibrinogen

The Journal of biological chemistry, 1985-10, Vol.260 (24), p.13095-13101

1985

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Inactivation of dopamine .beta.-hydroxylase by .beta.-ethynyltyramine: kinetic characterization and covalent modification of an active site peptide

Biochemistry (Easton), 1989-05, Vol.28 (9), p.3833-3842

1989

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Purification to apparent homogeneity and partial amino acid sequence of rat liver O 6 -alkylguanine-DNA-alkyltransferase

Nucleic acids research, 1990-01, Vol.18 (1), p.13-16

1990

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New drugs and emerging therapeutic targets in the endothelin signaling pathway and prospects for personalized precision medicine

Exploiting new genome data and Internet resources for the phylogenetic analysis of proteases, substrates and inhibitors

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

Has the yo-yo stopped? An assessment of human protein-coding gene number

The HtrA Family of Proteases: Implications for Protein Composition and Cell Fate

ASP1 (BACE2) Cleaves the Amyloid Precursor Protein at the β-Secretase Site

Extracting and connecting chemical structures from text sources using chemicalize.org

A genomic perspective on human proteases as drug targets

A genomic perspective on human proteases

The Concise Guide to PHARMACOLOGY 2015/16: Other ion channels

Assessing the protease and protease inhibitor content of the human genome

Splice variants: A homology modeling approach

Rat ATP citrate-lyase. Molecular cloning and sequence analysis of a full-length cDNA and mRNA abundance as a function of diet, organ, and age

The separation of glutathione transferase subunits by using reverse-phase high-pressure liquid chromatography

Website review: interPro (the integrated resource of protein domains and functional sites)

The glutathione transferase activity and tissue distribution of a cloned Mr28K protective antigen of Schistosoma mansoni

Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

Purification, properties, sequencing, and cloning of a lipoprotein-associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoproteins

Towards BioDBcore: a community-defined information specification for biological databases

3.19 - Examples of SAR-Centric Patent Mining Using Open Resources

The analysis of fibrinopeptide release from S--carboxymethylated fibrinogen chains using high-performance liquid chromatography

Identification, Genomic Organization, and mRNA Expression of LACTB, Encoding a Serine β-Lactamase-like Protein with an Amino-terminal Transmembrane Domain

Characterization of peptides cleaved by plasmin from the C-terminal polymerization domain of human fibrinogen

Inactivation of dopamine .beta.-hydroxylase by .beta.-ethynyltyramine: kinetic characterization and covalent modification of an active site peptide

Purification to apparent homogeneity and partial amino acid sequence of rat liver O 6 -alkylguanine-DNA-alkyltransferase

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