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Growth hormone, insulin-like growth factor-1 and the aging brain

Experimental gerontology, 2015-08, Vol.68, p.76-81

2015

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Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2

American journal of physiology. Heart and circulatory physiology, 2010-07, Vol.299 (1), p.H18-H24

2010

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Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype

The journals of gerontology. Series A, Biological sciences and medical sciences, 2018-06, Vol.73 (7), p.853-863

2018

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Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase

American journal of physiology. Heart and circulatory physiology, 2014-02, Vol.306 (3), p.H299-H308

2014

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Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging

Journal of neuroinflammation, 2017-07, Vol.14 (1), p.141-141, Article 141

2017

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IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

Aging cell, 2015-12, Vol.14 (6), p.1034-1044

2015

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Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses

Scientific reports, 2021-10, Vol.11 (1), p.20994-13, Article 20994

2021

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Interleukin 6 reduces allopregnanolone synthesis in the brain and contributes to age-related cognitive decline in mice

Journal of lipid research, 2020-10, Vol.61 (10), p.1308-1319

2020

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Whole brain radiation-induced impairments in learning and memory are time-sensitive and reversible by systemic hypoxia

PloS one, 2012-01, Vol.7 (1), p.e30444

2012

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Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome

Journal of neurochemistry, 2010-06, Vol.113 (6), p.1577-1588

2010

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Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging

Frontiers in aging neuroscience, 2022-03, Vol.14, p.788296-788296

2022

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Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes

Molecular metabolism (Germany), 2018-03, Vol.9, p.141-155

2018

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Gender and racial differences in endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease

Journal of vascular surgery, 2015-05, Vol.61 (5), p.1249-1257

2015

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Insulin-like growth factor-1 in CNS and cerebrovascular aging

Frontiers in aging neuroscience, 2013, Vol.5, p.27-27

2013

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Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia

American journal of physiology. Heart and circulatory physiology, 2011-04, Vol.300 (4), p.H1133-H1140

2011

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Regional changes in CNS and retinal glycerophospholipid profiles with age: a molecular blueprint

Journal of lipid research, 2017-04, Vol.58 (4), p.668-680

2017

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Hippocampal dysregulation of synaptic plasticity-associated proteins with age-related cognitive decline

Neurobiology of disease, 2011-07, Vol.43 (1), p.201-212

2011

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Aging Impairs Myogenic Adaptation to Pulsatile Pressure in Mouse Cerebral Arteries

Journal of cerebral blood flow and metabolism, 2015-01, Vol.35 (4), p.527-530

2015

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Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment

Journal of neuroinflammation, 2011-10, Vol.8 (1), p.138-138, Article 138

2011

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Progressive cognitive impairment after recovery from neuroinvasive and non-neuroinvasive Listeria monocytogenes infection

Frontiers in immunology, 2023-04, Vol.14, p.1146690-1146690

2023

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IGF‐1 Regulates Vertebral Bone Aging Through Sex‐Specific and Time‐Dependent Mechanisms

Journal of bone and mineral research, 2016-02, Vol.31 (2), p.443-454

2016

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Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells

The journals of gerontology. Series A, Biological sciences and medical sciences, 2015-06, Vol.70 (6), p.665-674

2015

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Neuroinvasive Listeria monocytogenes infection triggers accumulation of brain CD8 + tissue-resident memory T cells in a miR-155-dependent fashion

Journal of neuroinflammation, 2020-09, Vol.17 (1), p.259-259, Article 259

2020

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Association between daily walking and antioxidant capacity in patients with symptomatic peripheral artery disease

Journal of vascular surgery, 2017-06, Vol.65 (6), p.1762-1768

2017

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Irradiation Alters MMP-2/TIMP-2 System and Collagen Type IV Degradation in Brain

International journal of radiation oncology, biology, physics, 2012-04, Vol.82 (5), p.1559-1566

2012

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Growth hormone, insulin-like growth factor-1 and the aging brain

Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2

Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype

Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase

Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging

IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses

Interleukin 6 reduces allopregnanolone synthesis in the brain and contributes to age-related cognitive decline in mice

Whole brain radiation-induced impairments in learning and memory are time-sensitive and reversible by systemic hypoxia

Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome

Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging

Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes

Gender and racial differences in endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease

Insulin-like growth factor-1 in CNS and cerebrovascular aging

Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia

Regional changes in CNS and retinal glycerophospholipid profiles with age: a molecular blueprint

Hippocampal dysregulation of synaptic plasticity-associated proteins with age-related cognitive decline

Aging Impairs Myogenic Adaptation to Pulsatile Pressure in Mouse Cerebral Arteries

Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment

Progressive cognitive impairment after recovery from neuroinvasive and non-neuroinvasive Listeria monocytogenes infection

IGF‐1 Regulates Vertebral Bone Aging Through Sex‐Specific and Time‐Dependent Mechanisms

Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells

Neuroinvasive Listeria monocytogenes infection triggers accumulation of brain CD8 + tissue-resident memory T cells in a miR-155-dependent fashion

Association between daily walking and antioxidant capacity in patients with symptomatic peripheral artery disease

Irradiation Alters MMP-2/TIMP-2 System and Collagen Type IV Degradation in Brain

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