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MicroRNAs in Disease and Potential Therapeutic Applications

Molecular therapy, 2007-12, Vol.15 (12), p.2070-2079

2007

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Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents

Nucleic acids research, 2010-01, Vol.38 (1), p.e3-e3

2010

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A cytoplasmic pathway for gapmer antisense oligonucleotide-mediated gene silencing in mammalian cells

Nucleic acids research, 2015-10, Vol.43 (19), p.9350-9361

2015

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Direct Regulation of Androgen Receptor Activity by Potent CYP17 Inhibitors in Prostate Cancer Cells

The Journal of biological chemistry, 2012-02, Vol.287 (6), p.3777-3787

2012

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Silencing of gene expression by gymnotic delivery of antisense oligonucleotides

Methods in molecular biology (Clifton, N.J.), 2012-01, Vol.815, p.333

2012

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L1 Retrotransposition in Nondividing and Primary Human Somatic Cells

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (21), p.8036-8041

2006

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A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs

Nucleic acids research, 2008-11, Vol.36 (20), p.6511-6522

2008

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Infigratinib in Patients with Recurrent Gliomas and FGFR Alterations: A Multicenter Phase II Study

Clinical cancer research, 2022-06, Vol.28 (11), p.2270-2277

2022

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Infigratinib (BGJ398) in previously treated patients with advanced or metastatic cholangiocarcinoma with FGFR2 fusions or rearrangements: mature results from a multicentre, open-label, single-arm, phase 2 study

The lancet. Gastroenterology & hepatology, 2021-10, Vol.6 (10), p.803-815

2021

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In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses

Nature biotechnology, 2009-10, Vol.27 (10), p.925-932

2009

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Infigratinib in upper tract urothelial carcinoma versus urothelial carcinoma of the bladder and its association with comprehensive genomic profiling and/or cell‐free DNA results

Cancer, 2020-06, Vol.126 (11), p.2597-2606

2020

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Defining a Distinct Immunotherapy Eligible Subset of Patients with Cancer of Unknown Primary Using Gene Expression Profiling with the 92‐Gene Assay

The oncologist (Dayton, Ohio), 2020-11, Vol.25 (11), p.e1807-e1811

2020

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Tipifarnib Potentiates the Antitumor Effects of PI3Kα Inhibition in PIK3CA- and HRAS-Dysregulated HNSCC via Convergent Inhibition of mTOR Activity

Cancer research (Chicago, Ill.), 2023-10, Vol.83 (19), p.3252-3263

2023

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Abstract 1391: Gene expression profiling for cancer classification in circulating tumor cells

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1391-1391

2016

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siRNA target site secondary structure predictions using local stable substructures

Nucleic acids research, 2005-01, Vol.33 (3), p.e30-e30

2005

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A potential role for RNA interference in controlling the activity of the human LINE-1 retrotransposon

Nucleic acids research, 2005-01, Vol.33 (3), p.846-856

2005

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Performance and prognostic utility of the 92-gene assay in the molecular subclassification of ampullary adenocarcinoma

BMC cancer, 2016-08, Vol.16 (1), p.668-668, Article 668

2016

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Small interfering RNAs to the rescue: blocking L1 retrotransposition

Nature structural & molecular biology, 2006-09, Vol.13 (9), p.758-759

2006

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Abstract 2940: Molecular tumor profiling identifies actionable targets in patients with cholangiocarcinoma

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.2940-2940

2020

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Molecular classification of cancers with an uncertain diagnosis as candidates for immunotherapy

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.e23183-e23183

2017

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Molecular classification of neuroendocrine tumors: Clinical experience with the 92-gene assay in >24,000 cases

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.e15700-e15700

2017

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Clinical utilization of Breast Cancer Index (BCI) for late recurrence risk assessment and prediction of extended endocrine therapy (EET) benefit in early stage HR+ breast cancer

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.551-551

2017

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Circulating free DNA (cfDNA) and tissue next-generation sequencing analysis in a phase II study of infigratinib (BGJ398) for cholangiocarcinoma with FGFR2 fusions

Journal of clinical oncology, 2020-02, Vol.38 (4_suppl), p.579-579

2020

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Chemical modification patterns compatible with high potency dicer-substrate small interfering RNAs

Oligonucleotides, 2008-06, Vol.18 (2), p.187-200

2008

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MicroRNAs in Disease and Potential Therapeutic Applications

Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents

A cytoplasmic pathway for gapmer antisense oligonucleotide-mediated gene silencing in mammalian cells

Direct Regulation of Androgen Receptor Activity by Potent CYP17 Inhibitors in Prostate Cancer Cells

Silencing of gene expression by gymnotic delivery of antisense oligonucleotides

L1 Retrotransposition in Nondividing and Primary Human Somatic Cells

A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs

Infigratinib in Patients with Recurrent Gliomas and FGFR Alterations: A Multicenter Phase II Study

Infigratinib (BGJ398) in previously treated patients with advanced or metastatic cholangiocarcinoma with FGFR2 fusions or rearrangements: mature results from a multicentre, open-label, single-arm, phase 2 study

In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses

Infigratinib in upper tract urothelial carcinoma versus urothelial carcinoma of the bladder and its association with comprehensive genomic profiling and/or cell‐free DNA results

Defining a Distinct Immunotherapy Eligible Subset of Patients with Cancer of Unknown Primary Using Gene Expression Profiling with the 92‐Gene Assay

Tipifarnib Potentiates the Antitumor Effects of PI3Kα Inhibition in PIK3CA- and HRAS-Dysregulated HNSCC via Convergent Inhibition of mTOR Activity

Ziftomenib in relapsed or refractory acute myeloid leukaemia (KOMET-001): a multicentre, open-label, multi-cohort, phase 1 trial

Abstract 1391: Gene expression profiling for cancer classification in circulating tumor cells

siRNA target site secondary structure predictions using local stable substructures

A potential role for RNA interference in controlling the activity of the human LINE-1 retrotransposon

Performance and prognostic utility of the 92-gene assay in the molecular subclassification of ampullary adenocarcinoma

Small interfering RNAs to the rescue: blocking L1 retrotransposition

Abstract 2940: Molecular tumor profiling identifies actionable targets in patients with cholangiocarcinoma

Molecular classification of cancers with an uncertain diagnosis as candidates for immunotherapy

Molecular classification of neuroendocrine tumors: Clinical experience with the 92-gene assay in >24,000 cases

Clinical utilization of Breast Cancer Index (BCI) for late recurrence risk assessment and prediction of extended endocrine therapy (EET) benefit in early stage HR+ breast cancer

Circulating free DNA (cfDNA) and tissue next-generation sequencing analysis in a phase II study of infigratinib (BGJ398) for cholangiocarcinoma with FGFR2 fusions

Chemical modification patterns compatible with high potency dicer-substrate small interfering RNAs

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