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Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia

EMBO molecular medicine, 2020-04, Vol.12 (4), p.e10895-n/a

2020

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Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors

Nature medicine, 2015-12, Vol.21 (12), p.1481-1490

2015

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Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions

The Journal of experimental medicine, 2017-03, Vol.214 (3), p.719-735

2017

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Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells

Cell stem cell, 2011-06, Vol.8 (6), p.649-662

2011

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Collaboration between PcG Proteins and MLL Fusions in Leukemogenesis: An Emerging Paradigm

Cancer cell, 2011-11, Vol.20 (5), p.551-553

2011

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Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia

Cancer cell, 2016-01, Vol.29 (1), p.32-48

2016

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DNA damage accumulation and repair defects in acute myeloid leukemia: implications for pathogenesis, disease progression, and chemotherapy resistance

Chromosoma, 2014-12, Vol.123 (6), p.545-561

2014

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Protein arginine-methyltransferase-dependent oncogenesis

Nature cell biology, 2007-10, Vol.9 (10), p.1208-1215

2007

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The Histone Demethylase PHF8 Governs Retinoic Acid Response in Acute Promyelocytic Leukemia

Cancer cell, 2013-03, Vol.23 (3), p.376-389

2013

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SnapShot: Acute Myeloid Leukemia

Cancer cell, 2012-11, Vol.22 (5), p.698-698.e1

2012

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MLL-AF4, a double-edged sword for iPSC respecification into HSPCs

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (9), p.1964-1966

2018

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Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia

Blood, 2015-06, Vol.125 (25), p.3928-3936

2015

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Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia

Science translational medicine, 2021-02, Vol.13 (582)

2021

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Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML

Blood, 2023-12, Vol.142 (23), p.2002-2015

2023

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Mixed lineage leukemia protein in normal and leukemic stem cells

Experimental biology and medicine (Maywood, N.J.), 2013-03, Vol.238 (3), p.315-323

2013

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Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models

ACS medicinal chemistry letters, 2020-05, Vol.11 (5), p.754-759

2020

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A Knockout Combo: Eradicating AML Stem Cells with TKI plus SIRT1 Inhibition

Cell stem cell, 2014-10, Vol.15 (4), p.395-397

2014

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Sox4you: A New Player in C/EBPα Leukemia

Cancer cell, 2013-11, Vol.24 (5), p.557-559

2013

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Recruitment of RXR by Homotetrameric RARα Fusion Proteins Is Essential for Transformation

Cancer cell, 2007-07, Vol.12 (1), p.36-51

2007

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A novel application of furazolidone: anti-leukemic activity in acute myeloid leukemia

PloS one, 2013-08, Vol.8 (8), p.e72335

2013

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Linking MLL Leukemia with Integrin Signaling

Cancer cell, 2013-07, Vol.24 (1), p.5-7

2013

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Amplification of mixed lineage leukemia gene perturbs hematopoiesis and cooperates with partial tandem duplication to induce acute myeloid leukemia

Haematologica (Roma), 2017-08, Vol.102 (8), p.e300-e304

2017

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Follistatin is a novel therapeutic target and biomarker in FLT 3/ ITD acute myeloid leukemia

EMBO molecular medicine, 2020-04, Vol.12 (4)

2020

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Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia

EMBO molecular medicine, 2020-08, Vol.12 (8), p.e12911-n/a

2020

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Transforming activity of AML1-ETO is independent of CBFβ and ETO interaction but requires formation of homo-oligomeric complexes

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (8), p.2853-2858

2009

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Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia

Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors

Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions

Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells

Collaboration between PcG Proteins and MLL Fusions in Leukemogenesis: An Emerging Paradigm

Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia

DNA damage accumulation and repair defects in acute myeloid leukemia: implications for pathogenesis, disease progression, and chemotherapy resistance

Protein arginine-methyltransferase-dependent oncogenesis

The Histone Demethylase PHF8 Governs Retinoic Acid Response in Acute Promyelocytic Leukemia

SnapShot: Acute Myeloid Leukemia

MLL-AF4, a double-edged sword for iPSC respecification into HSPCs

Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia

Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia

Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML

Mixed lineage leukemia protein in normal and leukemic stem cells

Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models

A Knockout Combo: Eradicating AML Stem Cells with TKI plus SIRT1 Inhibition

Sox4you: A New Player in C/EBPα Leukemia

Recruitment of RXR by Homotetrameric RARα Fusion Proteins Is Essential for Transformation

A novel application of furazolidone: anti-leukemic activity in acute myeloid leukemia

Linking MLL Leukemia with Integrin Signaling

Amplification of mixed lineage leukemia gene perturbs hematopoiesis and cooperates with partial tandem duplication to induce acute myeloid leukemia

Follistatin is a novel therapeutic target and biomarker in FLT 3/ ITD acute myeloid leukemia

Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia

Transforming activity of AML1-ETO is independent of CBFβ and ETO interaction but requires formation of homo-oligomeric complexes

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