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Recent Advances in CRISPR/Cas9 Delivery Strategies

Biomolecules (Basel, Switzerland), 2020-05, Vol.10 (6), p.839

Yip, Bon Ham

2020

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Impact of Splicing Factor Mutations on Pre-mRNA Splicing in the Myelodysplastic Syndromes

Current pharmaceutical design, 2016-05, Vol.22 (16), p.2333

2016

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Silencing of ASXL1 impairs the granulomonocytic lineage potential of human CD34+ progenitor cells

British journal of haematology, 2013-03, Vol.160 (6), p.842-850

2013

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B cell class switch recombination is regulated by DYRK1A through MSH6 phosphorylation

Nature communications, 2023-03, Vol.14 (1), p.1462-1462, Article 1462

2023

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Production of Lentiviral Vectors Using Suspension Cells Grown in Serum-free Media

Molecular therapy. Methods & clinical development, 2020-06, Vol.17, p.58-68

2020

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ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts

Oncotarget, 2015-12, Vol.6 (42), p.44061-44071

2015

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PRR14L mutations are associated with chromosome 22 acquired uniparental disomy, age-related clonal hematopoiesis and myeloid neoplasia

Leukemia, 2019-05, Vol.33 (5), p.1184-1194

2019

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Mixed lineage leukemia protein in normal and leukemic stem cells

Experimental biology and medicine (Maywood, N.J.), 2013-03, Vol.238 (3), p.315-323

2013

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Mutation patterns of 16 genes in primary and secondary acute myeloid leukemia (AML) with normal cytogenetics

PloS one, 2012-08, Vol.7 (8), p.e42334-e42334

2012

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TP53 suppression promotes erythropoiesis in del(5q) MDS, suggesting a targeted therapeutic strategy in lenalidomide-resistant patients

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (40), p.16127-16132

2013

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The role of splicing factor mutations in the pathogenesis of the myelodysplastic syndromes

Advances in biological regulation, 2014-01, Vol.54, p.153-161

2014

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The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

The Journal of clinical investigation, 2017-06, Vol.127 (6), p.2206-2221

2017

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DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3

The Journal of clinical investigation, 2021-01, Vol.131 (1), p.1-18

2021

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L-leucine increases translation of RPS14 and LARP1 in erythroblasts from del(5q) myelodysplastic syndrome patients

Haematologica (Roma), 2018-11, Vol.103 (11), p.e496-e500

2018

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Lineage-Specific Aberrant mRNA Splicing By U2AF1 Mutation Alters Erythroid and Granulomonocytic Differentiation

Blood, 2015-12, Vol.126 (23), p.142-142

2015

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Amplification of mixed lineage leukemia gene perturbs hematopoiesis and cooperates with partial tandem duplication to induce acute myeloid leukemia

Haematologica (Roma), 2017-08, Vol.102 (8), p.e300-e304

2017

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Application of genome editing technologies to the study and treatment of hematological disease

Advances in biological regulation, 2016-01, Vol.60, p.122-134

2016

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Activation of the mTOR pathway by the amino acid l-leucine in the 5q- syndrome and other ribosomopathies

Advances in biological regulation, 2013-01, Vol.53 (1), p.8-17

2013

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The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

The Journal of clinical investigation, 2017-09, Vol.127 (9), p.3557-3557

2017

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The [U2AF1S.sup.34F] mutation induces lineage-specific splicing alterations in myelodysplastic syndromes.(RESEARCH ARTICLE)

The Journal of clinical investigation, 2017-09, Vol.127 (6), p.2206

2017

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The U2AF1^supS34F^ mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

The Journal of clinical investigation, 2017-06, Vol.127 (6), p.2206

2017

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Amplification of Histone Methyltransferase, Mixed-Lineage Leukemia (MLL), Perturbs Normal Hematopoiesis and Induces Hematological Disorder

Blood, 2009-11, Vol.114 (22), p.1965-1965

2009

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Aberration Of SF3B1 Results In Deregulated Splicing Of Key Genes and Pathways In Myelodysplastic Syndromes

Blood, 2013-11, Vol.122 (21), p.2747-2747

2013

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Silencing of ASXL 1 impairs the granulomonocytic lineage potential of human CD 34 + progenitor cells

British journal of haematology, 2013-03, Vol.160 (6), p.842-850

2013

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Recent Advances in CRISPR/Cas9 Delivery Strategies

Impact of Splicing Factor Mutations on Pre-mRNA Splicing in the Myelodysplastic Syndromes

Silencing of ASXL1 impairs the granulomonocytic lineage potential of human CD34+ progenitor cells

B cell class switch recombination is regulated by DYRK1A through MSH6 phosphorylation

Production of Lentiviral Vectors Using Suspension Cells Grown in Serum-free Media

ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts

PRR14L mutations are associated with chromosome 22 acquired uniparental disomy, age-related clonal hematopoiesis and myeloid neoplasia

Mixed lineage leukemia protein in normal and leukemic stem cells

Mutation patterns of 16 genes in primary and secondary acute myeloid leukemia (AML) with normal cytogenetics

TP53 suppression promotes erythropoiesis in del(5q) MDS, suggesting a targeted therapeutic strategy in lenalidomide-resistant patients

The role of splicing factor mutations in the pathogenesis of the myelodysplastic syndromes

The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3

3031 – CHROMOTHRIPSIS AND LEUKEMIC TRANSFORMATION IN MPN

L-leucine increases translation of RPS14 and LARP1 in erythroblasts from del(5q) myelodysplastic syndrome patients

Lineage-Specific Aberrant mRNA Splicing By U2AF1 Mutation Alters Erythroid and Granulomonocytic Differentiation

Amplification of mixed lineage leukemia gene perturbs hematopoiesis and cooperates with partial tandem duplication to induce acute myeloid leukemia

Application of genome editing technologies to the study and treatment of hematological disease

Activation of the mTOR pathway by the amino acid l-leucine in the 5q- syndrome and other ribosomopathies

The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

The [U2AF1S.sup.34F] mutation induces lineage-specific splicing alterations in myelodysplastic syndromes.(RESEARCH ARTICLE)

The U2AF1^supS34F^ mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

Amplification of Histone Methyltransferase, Mixed-Lineage Leukemia (MLL), Perturbs Normal Hematopoiesis and Induces Hematological Disorder

Aberration Of SF3B1 Results In Deregulated Splicing Of Key Genes and Pathways In Myelodysplastic Syndromes

Silencing of ASXL 1 impairs the granulomonocytic lineage potential of human CD 34 + progenitor cells

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