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Local protein kinase A action proceeds through intact holoenzymes

Science (American Association for the Advancement of Science), 2017-06, Vol.356 (6344), p.1288-1293

2017

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Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins

Proceedings of the National Academy of Sciences - PNAS, 2018-12, Vol.115 (49), p.E11465-E11474

2018

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Depletion of dAKAP1–protein kinase A signaling islands from the outer mitochondrial membrane alters breast cancer cell metabolism and motility

The Journal of biological chemistry, 2019-03, Vol.294 (9), p.3152-3168

2019

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Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation

eLife, 2013-11, Vol.2, p.e01319

2013

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Subcellular drug targeting illuminates local kinase action

eLife, 2019-12, Vol.8

2019

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An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma

eLife, 2019-05, Vol.8

2019

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VISTA checkpoint inhibition by pH-selective antibody SNS-101 with optimized safety and pharmacokinetic profiles enhances PD-1 response

Nature communications, 2024-04, Vol.15 (1), p.2917-2917, Article 2917

2024

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Attacking the one-out-of-m multicore problem by combining hardware management with mixed-criticality provisioning

Real-time systems, 2017-09, Vol.53 (5), p.709-759

2017

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Discovery of cellular substrates for protein kinase A using a peptide array screening protocol

Biochemical journal, 2011-08, Vol.438 (1), p.103-110

2011

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Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma

Cell reports (Cambridge), 2024-02, Vol.43 (2), p.113678-113678, Article 113678

2024

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Conditionally Active, pH-Sensitive Immunoregulatory Antibodies Targeting VISTA and CTLA-4 Lead an Emerging Class of Cancer Therapeutics

Antibodies (Basel), 2023-08, Vol.12 (3), p.55

2023

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AKAP-Lbc Mobilizes a Cardiac Hypertrophy Signaling Pathway

Molecular cell, 2008-10, Vol.32 (2), p.169-179

2008

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A-Kinase-Anchoring Protein-Lbc Connects Stress Signaling to Cardiac Hypertrophy

Molecular and cellular biology, 2013-01, Vol.33 (1), p.2-3

2013

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Scaffolding Proteins: Not Such Innocent Bystanders

Current biology, 2013-06, Vol.23 (12), p.R515-R517

2013

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Protein kinase A activation: Something new under the sun?

The Journal of cell biology, 2018-06, Vol.217 (6), p.1895-1897

2018

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Plugging PKA into ERK scaffolds

Cell cycle (Georgetown, Tex.), 2011-03, Vol.10 (5), p.731-732

2011

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A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface

The Journal of biological chemistry, 2020-07, Vol.295 (31), p.10749-10765

2020

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AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade

Nature cell biology, 2010-12, Vol.12 (12), p.1242-1249

2010

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Anchored cAMP signaling: Onward and upward – A short history of compartmentalized cAMP signal transduction

European journal of cell biology, 2006-07, Vol.85 (7), p.585-592

2006

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The Neuronal Actin-binding Proteins, Neurabin I and Neurabin II, Recruit Specific Isoforms of Protein Phosphatase-1 Catalytic Subunits

The Journal of biological chemistry, 2002-08, Vol.277 (31), p.27716-27724

2002

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E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis

The EMBO journal, 2014-03, Vol.33 (5), p.437-449

2014

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Hotspots of Aberrant Enhancer Activity in Fibrolamellar Carcinoma Reveal Candidate Oncogenic Pathways and Therapeutic Vulnerabilities

Cell reports (Cambridge), 2020-04, Vol.31 (2), p.107509-107509, Article 107509

2020

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Mislocalization of protein kinase A drives pathology in Cushing’s syndrome

Cell reports (Cambridge), 2022-07, Vol.40 (2), p.111073-111073, Article 111073

2022

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The where's and when's of kinase anchoring

Trends in biochemical sciences (Amsterdam. Regular ed.), 2006-06, Vol.31 (6), p.316-323

2006

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Proteomic, Functional, and Domain-Based Analysis of In Vivo 14-3-3 Binding Proteins Involved in Cytoskeletal Regulation and Cellular Organization

Current biology, 2004-08, Vol.14 (16), p.1436-1450

2004

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Local protein kinase A action proceeds through intact holoenzymes

Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins

Depletion of dAKAP1–protein kinase A signaling islands from the outer mitochondrial membrane alters breast cancer cell metabolism and motility

Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation

Subcellular drug targeting illuminates local kinase action

An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma

VISTA checkpoint inhibition by pH-selective antibody SNS-101 with optimized safety and pharmacokinetic profiles enhances PD-1 response

Attacking the one-out-of-m multicore problem by combining hardware management with mixed-criticality provisioning

Discovery of cellular substrates for protein kinase A using a peptide array screening protocol

Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma

Conditionally Active, pH-Sensitive Immunoregulatory Antibodies Targeting VISTA and CTLA-4 Lead an Emerging Class of Cancer Therapeutics

AKAP-Lbc Mobilizes a Cardiac Hypertrophy Signaling Pathway

A-Kinase-Anchoring Protein-Lbc Connects Stress Signaling to Cardiac Hypertrophy

Scaffolding Proteins: Not Such Innocent Bystanders

Protein kinase A activation: Something new under the sun?

Plugging PKA into ERK scaffolds

A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface

AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade

Anchored cAMP signaling: Onward and upward – A short history of compartmentalized cAMP signal transduction

The Neuronal Actin-binding Proteins, Neurabin I and Neurabin II, Recruit Specific Isoforms of Protein Phosphatase-1 Catalytic Subunits

E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis

Hotspots of Aberrant Enhancer Activity in Fibrolamellar Carcinoma Reveal Candidate Oncogenic Pathways and Therapeutic Vulnerabilities

Mislocalization of protein kinase A drives pathology in Cushing’s syndrome

The where's and when's of kinase anchoring

Proteomic, Functional, and Domain-Based Analysis of In Vivo 14-3-3 Binding Proteins Involved in Cytoskeletal Regulation and Cellular Organization

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