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Trans-synaptic spread of tau pathology in vivo

PloS one, 2012-02, Vol.7 (2), p.e31302-e31302

2012

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Isolating pathogenic mechanisms embedded within the hippocampal circuit through regional vulnerability

Neuron (Cambridge, Mass.), 2014-10, Vol.84 (1), p.32-39

Small, Scott A

2014

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Early Detection and Preventive Intervention in Schizophrenia: From Fantasy to Reality

The American journal of psychiatry, 2019-10, Vol.176 (10), p.794-810

2019

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RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease Risk

Neuron (Cambridge, Mass.), 2013-02, Vol.77 (3), p.425-439

2013

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Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease

Nature neuroscience, 2014-02, Vol.17 (2), p.304-311

2014

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Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures

Nature communications, 2018-01, Vol.9 (1), p.291-16, Article 291

2018

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Sorting through the Cell Biology of Alzheimer's Disease: Intracellular Pathways to Pathogenesis

Neuron (Cambridge, Mass.), 2006-10, Vol.52 (1), p.15-31

2006

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Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing

Cell reports (Cambridge), 2020-06, Vol.31 (9), p.107719-107719, Article 107719

2020

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Why Hippocampal Glutamate Levels Are Elevated in Schizophrenia

JAMA psychiatry (Chicago, Ill.), 2023-03, Vol.80 (3), p.274

2023

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Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer's disease-like pathology

Nature communications, 2017-11, Vol.8 (1), p.1464-14, Article 1464

2017

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Hippocampal Pathology in Clinical High-Risk Patients and the Onset of Schizophrenia

Biological psychiatry (1969), 2020-02, Vol.87 (3), p.234-242

2020

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Pharmacological chaperones in the age of proteomic pathology

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (34), p.12274-12275

Small, Scott A.

2014

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in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (13), p.5638-5643

2007

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Brain regions vulnerable and resistant to aging without Alzheimer's disease

PloS one, 2020-07, Vol.15 (7), p.e0234255-e0234255

2020

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Tau and other proteins found in Alzheimer's disease spinal fluid are linked to retromer-mediated endosomal traffic in mice and humans

Science translational medicine, 2020-11, Vol.12 (571)

2020

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Retromer deficiency in Tauopathy models enhances the truncation and toxicity of Tau

Nature communications, 2022-08, Vol.13 (1), p.5049-5049, Article 5049

2022

Volltextzugriff (PDF)

Insights into the role of diet and dietary flavanols in cognitive aging: results of a randomized controlled trial

Scientific reports, 2021-02, Vol.11 (1), p.3837-12, Article 3837

2021

Volltextzugriff (PDF)

Detecting schizophrenia with 3D structural brain MRI using deep learning

Scientific reports, 2023-09, Vol.13 (1), p.14433-14433, Article 14433

2023

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The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport

Neurobiology of disease, 2012-07, Vol.47 (1), p.126-134

2012

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Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system

Nature communications, 2013, Vol.4 (1), p.2250, Article 2250

2013

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A deep learning MRI approach outperforms other biomarkers of prodromal Alzheimer's disease

Alzheimer's research & therapy, 2022-03, Vol.14 (1), p.45-45, Article 45

2022

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Noninvasive, transcranial and localized opening of the blood-brain barrier using focused ultrasound in mice

Ultrasound in medicine & biology, 2007-01, Vol.33 (1), p.95-104

2007

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Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48

Science translational medicine, 2013-08, Vol.5 (200), p.200ra115

2013

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Stabilizing the Retromer Complex in a Human Stem Cell Model of Alzheimer’s Disease Reduces TAU Phosphorylation Independently of Amyloid Precursor Protein

Stem cell reports, 2018-03, Vol.10 (3), p.1046-1058

2018

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Interneuron precursor transplants in adult hippocampus reverse psychosis-relevant features in a mouse model of hippocampal disinhibition

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (20), p.7450-7455

2014

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Trans-synaptic spread of tau pathology in vivo

Isolating pathogenic mechanisms embedded within the hippocampal circuit through regional vulnerability

Early Detection and Preventive Intervention in Schizophrenia: From Fantasy to Reality

RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease Risk

Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease

Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures

Sorting through the Cell Biology of Alzheimer's Disease: Intracellular Pathways to Pathogenesis

Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing

Why Hippocampal Glutamate Levels Are Elevated in Schizophrenia

Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer's disease-like pathology

Hippocampal Pathology in Clinical High-Risk Patients and the Onset of Schizophrenia

Pharmacological chaperones in the age of proteomic pathology

in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus

Brain regions vulnerable and resistant to aging without Alzheimer's disease

Tau and other proteins found in Alzheimer's disease spinal fluid are linked to retromer-mediated endosomal traffic in mice and humans

Retromer deficiency in Tauopathy models enhances the truncation and toxicity of Tau

Insights into the role of diet and dietary flavanols in cognitive aging: results of a randomized controlled trial

Detecting schizophrenia with 3D structural brain MRI using deep learning

The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport

Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system

A deep learning MRI approach outperforms other biomarkers of prodromal Alzheimer's disease

Noninvasive, transcranial and localized opening of the blood-brain barrier using focused ultrasound in mice

Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48

Stabilizing the Retromer Complex in a Human Stem Cell Model of Alzheimer’s Disease Reduces TAU Phosphorylation Independently of Amyloid Precursor Protein

Interneuron precursor transplants in adult hippocampus reverse psychosis-relevant features in a mouse model of hippocampal disinhibition

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