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Environmental Enrichment Mitigates Cognitive Deficits in a Mouse Model of Alzheimer's Disease

The Journal of neuroscience, 2005-05, Vol.25 (21), p.5217-5224

2005

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APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1

Neurobiology of aging, 2004-08, Vol.25 (7), p.885-892

2004

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Intranuclear Inclusions and Neuritic Aggregates in Transgenic Mice Expressing a Mutant N-Terminal Fragment of Huntingtin

Human molecular genetics, 1999-03, Vol.8 (3), p.397-407

1999

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Persistent Amyloidosis following Suppression of Aβ Production in a Transgenic Model of Alzheimer Disease

PLoS medicine, 2005-12, Vol.2 (12), p.e355

2005

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Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo

Neuron (Cambridge, Mass.), 1996-07, Vol.17 (1), p.181-190

1996

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Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA

Neurobiology of disease, 2005-12, Vol.20 (3), p.943-952

2005

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Alzheimer Amyloid Protein Precursor in the Rat Hippocampus: Transport and Processing through the Perforant Path

The Journal of neuroscience, 1998-12, Vol.18 (23), p.9629-9637

1998

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Assessment of Normal and Mutant Human Presenilin Function in Caenorhabditis elegans

Proceedings of the National Academy of Sciences - PNAS, 1996-12, Vol.93 (25), p.14940-14944

1996

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Evidence That Levels of Presenilins (PS1 and PS2) Are Coordinately Regulated by Competition for Limiting Cellular Factors

The Journal of biological chemistry, 1997-11, Vol.272 (45), p.28415-28422

1997

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Expression of Presenilin 1 and 2 (PS1 and PS2) in Human and Murine Tissues

The Journal of neuroscience, 1996-12, Vol.16 (23), p.7513-7525

1996

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Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice

Human molecular genetics, 2004-08, Vol.13 (15), p.1599-1610

2004

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Protein Topology of Presenilin 1

Neuron (Cambridge, Mass.), 1996-11, Vol.17 (5), p.1023-1030

1996

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Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP)

The Journal of biological chemistry, 1994-01, Vol.269 (4), p.2637-2644

1994

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Endoproteolytic Processing and Stabilization of Wild-type and Mutant Presenilin

The Journal of biological chemistry, 1997-09, Vol.272 (39), p.24536-24541

1997

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Nuclear Accumulation of Truncated Atrophin-1 Fragments in a Transgenic Mouse Model of DRPLA

Neuron (Cambridge, Mass.), 1999-09, Vol.24 (1), p.275-286

1999

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Disease-associated Mutations at Copper Ligand Histidine Residues of Superoxide Dismutase 1 Diminish the Binding of Copper and Compromise Dimer Stability

The Journal of biological chemistry, 2007-01, Vol.282 (1), p.345-352

2007

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Multiple Effects of Aspartate Mutant Presenilin 1 on the Processing and Trafficking of Amyloid Precursor Protein

The Journal of biological chemistry, 2001-11, Vol.276 (46), p.43343-43350

2001

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Superoxide Dismutase 1 with Mutations Linked to Familial Amyotrophic Lateral Sclerosis Possesses Significant Activity

Proceedings of the National Academy of Sciences - PNAS, 1994-08, Vol.91 (17), p.8292-8296

1994

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β-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

Cell, 1995-05, Vol.81 (4), p.525-531

1995

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Hyperaccumulation of FAD-linked presenilin 1 variants in vivo

Nature medicine, 1997-07, Vol.3 (7), p.756-760

1997

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Familial Alzheimer's disease-linked presenilin 1 variants elevate A beta 1-42/1-40 ratio in vitro and in vivo

Neuron (Cambridge, Mass.), 1996-11, Vol.17 (5), p.1005-1013

1996

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Introduction and expression of the 400 kilobase precursor amyloid protein gene in transgenic mice

Nature genetics, 1993-09, Vol.5 (1), p.22-30

1993

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Altered Metabolism of Familial Alzheimer's Disease-Linked Amyloid Precursor Protein Variants in Yeast Artificial Chromosome Transgenic Mice

Human molecular genetics, 1997-09, Vol.6 (9), p.1535-1541

1997

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Rodent Aβ Modulates the Solubility and Distribution of Amyloid Deposits in Transgenic Mice

The Journal of biological chemistry, 2007-08, Vol.282 (31), p.22707-22720

2007

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Expression of stabilized beta-catenin in differentiated neurons of transgenic mice does not result in tumor formation

BMC cancer, 2002-12, Vol.2 (1), p.33-33, Article 33

2002

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Environmental Enrichment Mitigates Cognitive Deficits in a Mouse Model of Alzheimer's Disease

APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1

Intranuclear Inclusions and Neuritic Aggregates in Transgenic Mice Expressing a Mutant N-Terminal Fragment of Huntingtin

Persistent Amyloidosis following Suppression of Aβ Production in a Transgenic Model of Alzheimer Disease

Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo

Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA

Alzheimer Amyloid Protein Precursor in the Rat Hippocampus: Transport and Processing through the Perforant Path

Assessment of Normal and Mutant Human Presenilin Function in Caenorhabditis elegans

Evidence That Levels of Presenilins (PS1 and PS2) Are Coordinately Regulated by Competition for Limiting Cellular Factors

Expression of Presenilin 1 and 2 (PS1 and PS2) in Human and Murine Tissues

Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice

Protein Topology of Presenilin 1

Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP)

Endoproteolytic Processing and Stabilization of Wild-type and Mutant Presenilin

Nuclear Accumulation of Truncated Atrophin-1 Fragments in a Transgenic Mouse Model of DRPLA

Disease-associated Mutations at Copper Ligand Histidine Residues of Superoxide Dismutase 1 Diminish the Binding of Copper and Compromise Dimer Stability

Multiple Effects of Aspartate Mutant Presenilin 1 on the Processing and Trafficking of Amyloid Precursor Protein

Superoxide Dismutase 1 with Mutations Linked to Familial Amyotrophic Lateral Sclerosis Possesses Significant Activity

β-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

Hyperaccumulation of FAD-linked presenilin 1 variants in vivo

Familial Alzheimer's disease-linked presenilin 1 variants elevate A beta 1-42/1-40 ratio in vitro and in vivo

Introduction and expression of the 400 kilobase precursor amyloid protein gene in transgenic mice

Altered Metabolism of Familial Alzheimer's Disease-Linked Amyloid Precursor Protein Variants in Yeast Artificial Chromosome Transgenic Mice

Rodent Aβ Modulates the Solubility and Distribution of Amyloid Deposits in Transgenic Mice

Expression of stabilized beta-catenin in differentiated neurons of transgenic mice does not result in tumor formation

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