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Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects

Pharmacology & therapeutics (Oxford), 2007-12, Vol.116 (3), p.496-526

2007

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Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three‐Dimensional Spheroid Cultures of Primary Human Hepatocytes

Clinical pharmacology and therapeutics, 2020-10, Vol.108 (4), p.844-855

2020

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The Human Cytochrome P450 (CYP) Allele Nomenclature website: a peer-reviewed database of CYP variants and their associated effects

Human genomics, 2010-04, Vol.4 (4), p.278-281

2010

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Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment

Human genetics, 2010-01, Vol.127 (1), p.1-17

2010

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Pharmacogenetic biomarkers as tools for improved drug therapy; emphasis on the cytochrome P450 system

Biochemical and biophysical research communications, 2010-05, Vol.396 (1), p.90-94

2010

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The human cytochrome P450 Allele Nomenclature Committee Web site: submission criteria, procedures, and objectives

Methods in molecular biology (Clifton, N.J.), 2006, Vol.320, p.183

2006

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A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants

Clinical pharmacology and therapeutics, 2006-01, Vol.79 (1), p.103-113

2006

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Intronic polymorphisms of cytochromes P450

Human genomics, 2010-08, Vol.4 (6), p.402-405

2010

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Kinetics of omeprazole and escitalopram in relation to the CYP2C1917 allele in healthy subjects

European journal of clinical pharmacology, 2008-12, Vol.64 (12), p.1175-1179

2008

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Pharmacogenomic biomarkers: new tools in current and future drug therapy

Trends in pharmacological sciences (Regular ed.), 2011-02, Vol.32 (2), p.72-81

2011

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Generation of mice transgenic for human CYP2C18 and CYP2C19: characterization of the sexually dimorphic gene and enzyme expression

Drug metabolism and disposition, 2008-05, Vol.36 (5), p.955-962

2008

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CYP1A21F contains the −163C>A substitution and is highly inducible

Pharmacogenetics and genomics, 2013-02, Vol.23 (2), p.104-105

Sim, Sarah C

2013

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Update on allele nomenclature for human cytochromes P450 and the Human Cytochrome P450 Allele (CYP-allele) Nomenclature Database

Methods in molecular biology (Clifton, N.J.), 2013, Vol.987, p.251

2013

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Databases in the area of pharmacogenetics

Human mutation, 2011-05, Vol.32 (5), p.526-531

2011

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CYP2D6 update: revised nomenclature for CYP2D7/2D6 hybrid genes

Pharmacogenetics and genomics, 2012-09, Vol.22 (9), p.692-694

2012

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Linkage disequilibrium between the CYP2C1917 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations

European journal of clinical pharmacology, 2010-12, Vol.66 (12), p.1199-1205

2010

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Linkage disequilibrium between the CYP2C1917 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations

European journal of clinical pharmacology, 2010-12, Vol.66 (12), p.1199-1205

2010

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Association between CYP2C19 polymorphism and depressive symptoms

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2010-09, Vol.153B (6), p.1160-1166

2010

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Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample

Journal of affective disorders, 2013-03, Vol.146 (1), p.91-99

2013

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CYP3A7 protein expression is high in a fraction of adult human livers and partially associated with the CYP3A71C allele

Pharmacogenetics and genomics, 2005-09, Vol.15 (9), p.625-631

2005

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The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C1935 and CYP2C192 Alleles

Drug metabolism and disposition, 2015-08, Vol.43 (8), p.1226-1235

2015

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Institutional Profile: Karolinska Institutet

Pharmacogenomics, 2012-12, Vol.13 (16), p.1887-1891

2012

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Nomenclature for alleles of the cytochrome P450 oxidoreductase gene

Pharmacogenetics and genomics, 2009-07, Vol.19 (7), p.565-566

2009

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Coffee, myocardial infarction, and CYP nomenclature

JAMA : the journal of the American Medical Association, 2006-08, Vol.296 (7), p.764

2006

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CYP1A21F contains the - 163C >A substitution and is highly inducible (vol 23, pg 104, 2013)

Pharmacogenetics and genomics, 2013-04, Vol.23 (4), p.249

Sim, SC

2013

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Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects

Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three‐Dimensional Spheroid Cultures of Primary Human Hepatocytes

The Human Cytochrome P450 (CYP) Allele Nomenclature website: a peer-reviewed database of CYP variants and their associated effects

Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment

Pharmacogenetic biomarkers as tools for improved drug therapy; emphasis on the cytochrome P450 system

The human cytochrome P450 Allele Nomenclature Committee Web site: submission criteria, procedures, and objectives

A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants

Intronic polymorphisms of cytochromes P450

Kinetics of omeprazole and escitalopram in relation to the CYP2C1917 allele in healthy subjects

Pharmacogenomic biomarkers: new tools in current and future drug therapy

Generation of mice transgenic for human CYP2C18 and CYP2C19: characterization of the sexually dimorphic gene and enzyme expression

CYP1A21F contains the −163C>A substitution and is highly inducible

Update on allele nomenclature for human cytochromes P450 and the Human Cytochrome P450 Allele (CYP-allele) Nomenclature Database

Databases in the area of pharmacogenetics

CYP2D6 update: revised nomenclature for CYP2D7/2D6 hybrid genes

Linkage disequilibrium between the CYP2C1917 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations

Linkage disequilibrium between the CYP2C1917 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations

Association between CYP2C19 polymorphism and depressive symptoms

Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample

CYP3A7 protein expression is high in a fraction of adult human livers and partially associated with the CYP3A71C allele

The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C1935 and CYP2C192 Alleles

Institutional Profile: Karolinska Institutet

Nomenclature for alleles of the cytochrome P450 oxidoreductase gene

Coffee, myocardial infarction, and CYP nomenclature

CYP1A21F contains the - 163C >A substitution and is highly inducible (vol 23, pg 104, 2013)

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