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A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma

Cancer discovery, 2012-08, Vol.2 (8), p.685-693

2012

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Oncogenic mutant RAS signaling activity is rescaled by the ERK/MAPK pathway

Molecular systems biology, 2020-10, Vol.16 (10), p.e9518-n/a

2020

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Inhibition of mitochondrial function induces an integrated stress response in oligodendroglia

Neurobiology of disease, 2009-05, Vol.34 (2), p.357-365

2009

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PIK3CA‐mutated melanoma cells rely on cooperative signaling through mTORC1/2 for sustained proliferation

Pigment cell and melanoma research, 2017-05, Vol.30 (3), p.353-367

2017

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The fastest Western in town: a contemporary twist on the classic Western blot analysis

Journal of visualized experiments, 2014-02 (84), p.e51149-e51149

2014

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BRAFV600E cooperates with PI3K signaling, independent of AKT, to regulate melanoma cell proliferation

Molecular cancer research, 2014-03, Vol.12 (3), p.447-463

2014

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Abstract 1087: NF1 regulates the RAS-related GTPases, RRAS and RRAS2, independent of RAS activity

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.1087-1087

2020

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Abstract B11: Oncogenic KRAS regulates 4E-BP1, a repressor of cap-dependent translation, independently of growth factor activity

Cancer research (Chicago, Ill.), 2017-03, Vol.77 (6_Supplement), p.B11-B11

2017

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BRAF V600E ‐ and PI3′K‐activated signaling pathways cooperate to regulate phosphorylation of ribosomal protein S6 in human melanoma cells

The FASEB journal, 2012-04, Vol.26 (S1)

2012

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Expression and activity of poly(ADP-ribose) glycohydrolase in cultured astrocytes, neurons, and C6 glioma cells

Brain research. Molecular brain research., 2003-10, Vol.117 (2), p.213-220

2003

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BRAFV600E Cooperates With PI3’-Kinase Signaling, Independent of AKT, To Regulate Melanoma Cell Proliferation

Molecular cancer research, 2014-01, Vol.12 (3), p.447-463

2014

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Abstract 29: MEK and PI3K signaling cooperate through mTORC1/2 to promote PIK3CA mutant melanoma cell proliferation

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.29-29

2016

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Abstract 1370: EGFR-mediated Spred1 phosphorylation inhibits NF1 to sustain constitutive Ras/MAPK signaling

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1370-1370

2017

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The Fastest Western in Town: A Contemporary Twist on the Classic Western Blot Analysis

Journal of visualized experiments, 2014-02 (84)

2014

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Abstract IA29: PI3′ -kinase inhibition forestalls the onset of MEK1/2 inhibitor resistance in BRAFV600E/PTENNull melanoma

Cancer research (Chicago, Ill.), 2015-07, Vol.75 (14_Supplement), p.IA29-IA29

2015

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Abstract A09: Cooperation of the MAPK and PI3K>AKT>mTORC1 signaling pathways is required for PIK3CA mutant melanoma maintenance

Molecular cancer therapeutics, 2015-07, Vol.14 (7_Supplement), p.A09-A09

2015

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Abstract LB_C09: QTX3034, a potent and selective multi-KRAS inhibitor, synergizes with EGFR inhibitors and enhances anti-tumor activity

Molecular cancer therapeutics, 2023-12, Vol.22 (12_Supplement), p.LB_C09-LB_C09

2023

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Abstract LB320: Discovery and characterization of QTX3034, a potent, selective, and orally bioavailable allosteric KRAS inhibitor

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (8_Supplement), p.LB320-LB320

2023

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Abstract LB321: Discovery and characterization of QTX3046, a potent, selective, and orally bioavailable non-covalent KRASG12D inhibitor

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (8_Supplement), p.LB321-LB321

2023

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Abstract LB163: Discovery and characterization of QTX3544, a potent, selective, and orally bioavailable allosteric G12V preferring multi KRAS inhibitor

Cancer research (Chicago, Ill.), 2024-04, Vol.84 (7_Supplement), p.LB163-LB163

2024

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Mitochondrial inhibition induces PERK‐dependent activation of the unfolded protein response stress pathway in human oligodendroglial cells

The FASEB journal, 2008-04, Vol.22 (S2), p.303-303

2008

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Distinguishing features of long COVID identified through immune profiling

Nature (London), 2023-11, Vol.623 (7985), p.139-148

2023

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Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice

Science (American Association for the Advancement of Science), 2016-11, Vol.354 (6314), p.904-908

2016

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Role of glucosyltransferase R in biofilm interactions between Streptococcus oralis and Candida albicans

The ISME Journal, 2020-05, Vol.14 (5), p.1207-1222

2020

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The formation of inflammatory demyelinated lesions in cerebral white matter

Annals of neurology, 2014-10, Vol.76 (4), p.594-608

2014

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A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma

Oncogenic mutant RAS signaling activity is rescaled by the ERK/MAPK pathway

Inhibition of mitochondrial function induces an integrated stress response in oligodendroglia

PIK3CA‐mutated melanoma cells rely on cooperative signaling through mTORC1/2 for sustained proliferation

The fastest Western in town: a contemporary twist on the classic Western blot analysis

BRAFV600E cooperates with PI3K signaling, independent of AKT, to regulate melanoma cell proliferation

Abstract 1087: NF1 regulates the RAS-related GTPases, RRAS and RRAS2, independent of RAS activity

Abstract B11: Oncogenic KRAS regulates 4E-BP1, a repressor of cap-dependent translation, independently of growth factor activity

BRAF V600E ‐ and PI3′K‐activated signaling pathways cooperate to regulate phosphorylation of ribosomal protein S6 in human melanoma cells

Expression and activity of poly(ADP-ribose) glycohydrolase in cultured astrocytes, neurons, and C6 glioma cells

BRAFV600E Cooperates With PI3’-Kinase Signaling, Independent of AKT, To Regulate Melanoma Cell Proliferation

Abstract 29: MEK and PI3K signaling cooperate through mTORC1/2 to promote PIK3CA mutant melanoma cell proliferation

Abstract 1370: EGFR-mediated Spred1 phosphorylation inhibits NF1 to sustain constitutive Ras/MAPK signaling

The Fastest Western in Town: A Contemporary Twist on the Classic Western Blot Analysis

Abstract IA29: PI3′ -kinase inhibition forestalls the onset of MEK1/2 inhibitor resistance in BRAFV600E/PTENNull melanoma

Abstract A09: Cooperation of the MAPK and PI3K>AKT>mTORC1 signaling pathways is required for PIK3CA mutant melanoma maintenance

Abstract LB_C09: QTX3034, a potent and selective multi-KRAS inhibitor, synergizes with EGFR inhibitors and enhances anti-tumor activity

Abstract LB320: Discovery and characterization of QTX3034, a potent, selective, and orally bioavailable allosteric KRAS inhibitor

Abstract LB321: Discovery and characterization of QTX3046, a potent, selective, and orally bioavailable non-covalent KRASG12D inhibitor

Abstract LB163: Discovery and characterization of QTX3544, a potent, selective, and orally bioavailable allosteric G12V preferring multi KRAS inhibitor

Mitochondrial inhibition induces PERK‐dependent activation of the unfolded protein response stress pathway in human oligodendroglial cells

Distinguishing features of long COVID identified through immune profiling

Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice

Role of glucosyltransferase R in biofilm interactions between Streptococcus oralis and Candida albicans

The formation of inflammatory demyelinated lesions in cerebral white matter

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