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Selective induction of cancer cell death by VDAC1‐based peptides and their potential use in cancer therapy

Molecular oncology, 2018-06, Vol.12 (7), p.1077-1103

2018

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VDAC1 in the diseased myocardium and the effect of VDAC1-interacting compound on atrial fibrosis induced by hyperaldosteronism

Scientific reports, 2020-12, Vol.10 (1), p.22101-22101, Article 22101

2020

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SMAC/Diablo controls proliferation of cancer cells by regulating phosphatidylethanolamine synthesis

Molecular oncology, 2021-11, Vol.15 (11), p.3037-3061

2021

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VDAC1 functions in Ca2+ homeostasis and cell life and death in health and disease

Cell calcium (Edinburgh), 2018-01, Vol.69, p.81-100

2018

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VDAC1 and the TSPO: Expression, Interactions, and Associated Functions in Health and Disease States

International journal of molecular sciences, 2019-07, Vol.20 (13), p.3348

2019

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VDAC1 at the Intersection of Cell Metabolism, Apoptosis, and Diseases

Biomolecules (Basel, Switzerland), 2020-10, Vol.10 (11), p.1485

2020

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Voltage-dependent Anion Channel 1-based Peptides Interact with Bcl-2 to Prevent Antiapoptotic Activity

The Journal of biological chemistry, 2010-02, Vol.285 (9), p.6053-6062

2010

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Oligomerization of the Mitochondrial Protein Voltage-Dependent Anion Channel Is Coupled to the Induction of Apoptosis

Molecular and Cellular Biology, 2010-12, Vol.30 (24), p.5698-5709

2010

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Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide

Neoplasia (New York, N.Y.), 2018-06, Vol.20 (6), p.594-609

2018

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VDAC1-interacting anion transport inhibitors inhibit VDAC1 oligomerization and apoptosis

Biochimica et biophysica acta, 2016-07, Vol.1863 (7), p.1612-1623

2016

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VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease

Science (American Association for the Advancement of Science), 2019-12, Vol.366 (6472), p.1531-1536

2019

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Voltage-Dependent Anion Channel 1 As an Emerging Drug Target for Novel Anti-Cancer Therapeutics

Frontiers in oncology, 2017-07, Vol.7, p.154-154

2017

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The role of calcium in VDAC1 oligomerization and mitochondria-mediated apoptosis

Biochimica et biophysica acta, 2013-07, Vol.1833 (7), p.1745-1754

2013

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NCLX is an essential component of mitochondrial Na⁺/Ca²⁺ exchange

Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (1), p.436-441

2010

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Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALS

Neuron (Cambridge, Mass.), 2010-08, Vol.67 (4), p.575-587

2010

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Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction

The Journal of biological chemistry, 2016-11, Vol.291 (48), p.24986-25003

2016

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Voltage-dependent Anion Channel 1-based Peptides Interact with Hexokinase to Prevent Its Anti-apoptotic Activity

The Journal of biological chemistry, 2009-02, Vol.284 (6), p.3946-3955

2009

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Metabolic Reprograming Via Silencing of Mitochondrial VDAC1 Expression Encourages Differentiation of Cancer Cells

Molecular therapy. Nucleic acids, 2019-09, Vol.17, p.24-37

2019

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Adverse Effects of Metformin From Diabetes to COVID-19, Cancer, Neurodegenerative Diseases, and Aging: Is VDAC1 a Common Target?

Frontiers in physiology, 2021-10, Vol.12, p.730048-730048

2021

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Uncovering the role of VDAC in the regulation of cell life and death

Journal of bioenergetics and biomembranes, 2008-06, Vol.40 (3), p.183-191

2008

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VDAC1 at the crossroads of cell metabolism, apoptosis and cell stress

Cell Stress, 2017-10, Vol.1 (1), p.11-36

2017

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Apoptosis is regulated by the VDAC1 N-terminal region and by VDAC oligomerization: release of cytochrome c, AIF and Smac/Diablo

Biochimica et biophysica acta, 2010-06, Vol.1797 (6-7), p.1281-1291

2010

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The Expression Level of the Voltage-Dependent Anion Channel Controls Life and Death of the Cell

Proceedings of the National Academy of Sciences - PNAS, 2006-04, Vol.103 (15), p.5787-5792

2006

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Mitochondrial VDAC, the Na+/Ca2+ Exchanger, and the Ca2+ Uniporter in Ca2+ Dynamics and Signaling

Membrane Dynamics and Calcium Signaling, p.323-347

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Key regions of VDAC1 functioning in apoptosis induction and regulation by hexokinase

Biochimica et biophysica acta, 2009-05, Vol.1787 (5), p.421-430

2009

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Selective induction of cancer cell death by VDAC1‐based peptides and their potential use in cancer therapy

VDAC1 in the diseased myocardium and the effect of VDAC1-interacting compound on atrial fibrosis induced by hyperaldosteronism

SMAC/Diablo controls proliferation of cancer cells by regulating phosphatidylethanolamine synthesis

VDAC1 functions in Ca2+ homeostasis and cell life and death in health and disease

VDAC1 and the TSPO: Expression, Interactions, and Associated Functions in Health and Disease States

VDAC1 at the Intersection of Cell Metabolism, Apoptosis, and Diseases

Voltage-dependent Anion Channel 1-based Peptides Interact with Bcl-2 to Prevent Antiapoptotic Activity

Oligomerization of the Mitochondrial Protein Voltage-Dependent Anion Channel Is Coupled to the Induction of Apoptosis

Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide

VDAC1-interacting anion transport inhibitors inhibit VDAC1 oligomerization and apoptosis

VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease

Voltage-Dependent Anion Channel 1 As an Emerging Drug Target for Novel Anti-Cancer Therapeutics

The role of calcium in VDAC1 oligomerization and mitochondria-mediated apoptosis

NCLX is an essential component of mitochondrial Na⁺/Ca²⁺ exchange

Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALS

Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction

Voltage-dependent Anion Channel 1-based Peptides Interact with Hexokinase to Prevent Its Anti-apoptotic Activity

Metabolic Reprograming Via Silencing of Mitochondrial VDAC1 Expression Encourages Differentiation of Cancer Cells

Adverse Effects of Metformin From Diabetes to COVID-19, Cancer, Neurodegenerative Diseases, and Aging: Is VDAC1 a Common Target?

Uncovering the role of VDAC in the regulation of cell life and death

VDAC1 at the crossroads of cell metabolism, apoptosis and cell stress

Apoptosis is regulated by the VDAC1 N-terminal region and by VDAC oligomerization: release of cytochrome c, AIF and Smac/Diablo

The Expression Level of the Voltage-Dependent Anion Channel Controls Life and Death of the Cell

Mitochondrial VDAC, the Na+/Ca2+ Exchanger, and the Ca2+ Uniporter in Ca2+ Dynamics and Signaling

Key regions of VDAC1 functioning in apoptosis induction and regulation by hexokinase

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