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Quantification of Alzheimer pathology in ageing and dementia: age-related accumulation of amyloid-β(42) peptide in vascular dementia

Neuropathology and applied neurobiology, 2006-04, Vol.32 (2), p.103-118

2006

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Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

Nature (London), 2000-06, Vol.405 (6787), p.689-694

2000

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L-685,458, an Aspartyl Protease Transition State Mimic, Is a Potent Inhibitor of Amyloid β-Protein Precursor γ-Secretase Activity

Biochemistry (Easton), 2000-08, Vol.39 (30), p.8698-8704

2000

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Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders

Molecular and cellular neuroscience, 2004-01, Vol.25 (1), p.42-55

2004

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Inhibition of PC12 Cell Redox Activity is a Specific, Early Indicator of the Mechanism of β-Amyloid-Mediated Cell Death

Proceedings of the National Academy of Sciences - PNAS, 1994-02, Vol.91 (4), p.1470-1474

1994

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Two domains within the first putative transmembrane domain of presenilin 1 differentially influence presenilinase and γ‐secretase activity

Journal of neurochemistry, 2005-09, Vol.94 (5), p.1315-1328

2005

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The toxicity in vitro of beta-amyloid protein

Biochemical journal, 1995-10, Vol.311 ( Pt 1) (1), p.1-16

1995

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The Intracellular Component of Cellular 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide (MTT) Reduction Is Specifically Inhibited by β‐Amyloid Peptides

Journal of neurochemistry, 1995-07, Vol.65 (1), p.218-227

1995

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Subcellular targeting of DISC1 is dependent on a domain independent from the Nudel binding site

Molecular and cellular neuroscience, 2005-04, Vol.28 (4), p.613-624

2005

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Modulation of ion channel activity: a key function of the protein kinase C enzyme family

Pharmacological reviews, 1989-06, Vol.41 (2), p.211

1989

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Determination of guinea-pig cortical γ-secretase activity ex vivo following the systemic administration of a γ-secretase inhibitor

Neuropharmacology, 2005-06, Vol.48 (7), p.1002-1011

2005

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Receptor for advanced glycation endproducts (RAGE) exhibits highly differential cellular and subcellular localisation in rat and human lung

Cellular and molecular biology (Noisy-le-Grand, France), 1998-11, Vol.44 (7), p.1147

1998

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Presenilin-Dependent γ-Secretase Activity Modulates Thymocyte Development

Proceedings of the National Academy of Sciences - PNAS, 2001-07, Vol.98 (16), p.9312-9317

2001

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Gamma-secretase inhibition

Biochemical Society transactions, 2002-08, Vol.30 (4), p.534

2002

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Sulfated glycosaminoglycans and dyes attenuate the neurotoxic effects of β-amyloid in rat PC12 cells

Neuroscience letters, 1995-01, Vol.184 (2), p.113-116

1995

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Sulfonated dyes attenuate the toxic effects of β-amyloid in a structure-specific fashion

Neuroscience letters, 1995-09, Vol.197 (3), p.211-214

1995

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Cellular MTT reduction distinguishes the mechanism of action of β-amyloid from that of tachykinin receptor peptides

Neuropeptides (Edinburgh), 1996-04, Vol.30 (2), p.125-132

Shearman, M.S

1996

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Differential expression of multiple protein kinase C subspecies in rat central nervous tissue

Biochemical and biophysical research communications, 1987-09, Vol.147 (3), p.911-919

1987

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Selective activation of the γ‐subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites

FEBS letters, 1989-01, Vol.243 (2), p.177-182

1989

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Distinct cellular expression of beta I- and beta II-subspecies of protein kinase C in rat cerebellum

The Journal of neuroscience, 1988-10, Vol.8 (10), p.3850-3856

1988

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Pharmacological knock-down of the presenilin 1 heterodimer by a novel gamma -secretase inhibitor: implications for presenilin biology

The Journal of biological chemistry, 2001-11, Vol.276 (48), p.45394-45402

2001

Volltextzugriff (PDF)

Synaptosomal Protein Kinase C Subspecies: B. Down‐Regulation Promoted by Phorbol Ester and Its Effect on Evoked Norepinephrine Release

Journal of neurochemistry, 1991-04, Vol.56 (4), p.1263-1269

1991

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Mouse cortical neurones lacking APP show normal neurite outgrowth and survival responses in vitro

Neuroreport, 1998-09, Vol.9 (13), p.3053-3058

1998

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Protein kinase C subspecies in adult rat hippocampal synaptosomes Activation by diacylglycerol and arachidonic acid

FEBS letters, 1991-02, Vol.279 (2), p.261-264

1991

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Quantification of Alzheimer pathology in ageing and dementia: age-related accumulation of amyloid-β(42) peptide in vascular dementia

Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1

L-685,458, an Aspartyl Protease Transition State Mimic, Is a Potent Inhibitor of Amyloid β-Protein Precursor γ-Secretase Activity

Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders

Inhibition of PC12 Cell Redox Activity is a Specific, Early Indicator of the Mechanism of β-Amyloid-Mediated Cell Death

Two domains within the first putative transmembrane domain of presenilin 1 differentially influence presenilinase and γ‐secretase activity

The toxicity in vitro of beta-amyloid protein

The Intracellular Component of Cellular 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide (MTT) Reduction Is Specifically Inhibited by β‐Amyloid Peptides

Subcellular targeting of DISC1 is dependent on a domain independent from the Nudel binding site

Modulation of ion channel activity: a key function of the protein kinase C enzyme family

Determination of guinea-pig cortical γ-secretase activity ex vivo following the systemic administration of a γ-secretase inhibitor

Receptor for advanced glycation endproducts (RAGE) exhibits highly differential cellular and subcellular localisation in rat and human lung

Presenilin-Dependent γ-Secretase Activity Modulates Thymocyte Development

Gamma-secretase inhibition

Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation

Sulfated glycosaminoglycans and dyes attenuate the neurotoxic effects of β-amyloid in rat PC12 cells

Sulfonated dyes attenuate the toxic effects of β-amyloid in a structure-specific fashion

Cellular MTT reduction distinguishes the mechanism of action of β-amyloid from that of tachykinin receptor peptides

Differential expression of multiple protein kinase C subspecies in rat central nervous tissue

Selective activation of the γ‐subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites

Distinct cellular expression of beta I- and beta II-subspecies of protein kinase C in rat cerebellum

Pharmacological knock-down of the presenilin 1 heterodimer by a novel gamma -secretase inhibitor: implications for presenilin biology

Synaptosomal Protein Kinase C Subspecies: B. Down‐Regulation Promoted by Phorbol Ester and Its Effect on Evoked Norepinephrine Release

Mouse cortical neurones lacking APP show normal neurite outgrowth and survival responses in vitro

Protein kinase C subspecies in adult rat hippocampal synaptosomes Activation by diacylglycerol and arachidonic acid

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