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A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (8), p.E1054-E1063

2016

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Molecular mechanisms of retroviral integration site selection

Nucleic acids research, 2014-09, Vol.42 (16), p.10209-10225

2014

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Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

Retrovirology, 2009-03, Vol.6 (1), p.25-25, Article 25

2009

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Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74

Journal of virology, 2016-06, Vol.90 (12), p.5808-5823

2016

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Host and viral determinants for MxB restriction of HIV-1 infection

Retrovirology, 2014-10, Vol.11 (1), p.90-90, Article 90

2014

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Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase–LEDGF/p75 interaction

Bioorganic & medicinal chemistry, 2013-10, Vol.21 (19), p.5963-5972

2013

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Biochemical characterization of novel retroviral integrase proteins

PloS one, 2013-10, Vol.8 (10), p.e76638-e76638

2013

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Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity

Cell reports (Cambridge), 2016-12, Vol.17 (12), p.3178-3192

2016

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The Competitive Interplay between Allosteric HIV‑1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV‑1 Replication Adversely Affects Inhibitor Potency

ACS chemical biology, 2016-05, Vol.11 (5), p.1313-1321

2016

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Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration

PLoS pathogens, 2016-08, Vol.12 (8), p.e1005860-e1005860

2016

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Correction: Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration

PLoS pathogens, 2016-10, Vol.12 (10), p.e1005956-e1005956

2016

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A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication

PloS one, 2012-09, Vol.7 (9), p.e45177

2012

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Haematopoietic stem and progenitor cells from human pluripotent stem cells

Nature (London), 2017-05, Vol.545 (7655), p.432-438

2017

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Structural basis for retroviral integration into nucleosomes

Nature (London), 2015-07, Vol.523 (7560), p.366-369

2015

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Distinct viral reservoirs in individuals with spontaneous control of HIV-1

Nature (London), 2020-09, Vol.585 (7824), p.261-267

2020

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Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

Retrovirology, 2009-04, Vol.6 (1), p.33-33

2009

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Implementation of a Sickle Cell Disease Screening Initiative in Uganda with HemoTypeSCTM

Blood, 2018-11, Vol.132 (Supplement 1), p.LBA-3-LBA-3

2018

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Fragment-Based Discovery of 8‑Hydroxyquinoline Inhibitors of the HIV‑1 Integrase–Lens Epithelium-Derived Growth Factor/p75 (IN–LEDGF/p75) Interaction

Journal of medicinal chemistry, 2013-03, Vol.56 (6), p.2311-2322

2013

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Sites of retroviral DNA integration: From basic research to clinical applications

Critical reviews in biochemistry and molecular biology, 2016-01, Vol.51 (1), p.26-42

2016

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Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites

Journal of visualized experiments, 2016-03 (109)

2016

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HemoTypeSC Demonstrates >99% Field Accuracy in a Sickle Cell Disease Screening Initiative in Children of Southeastern Uganda

American journal of hematology, 2019-06, Vol.94 (6), p.E164-E166

2019

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A supramolecular assembly mediates lentiviral DNA integration

Science (American Association for the Advancement of Science), 2017-01, Vol.355 (6320), p.93-95

2017

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Structural basis for spumavirus GAG tethering to chromatin

Proceedings of the National Academy of Sciences - PNAS, 2017-05, Vol.114 (21), p.5509-5514

2017

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Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding

Nucleic acids research, 2014-04, Vol.42 (8), p.5164-5176

2014

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Point‐of‐care screening for sickle cell disease in low‐resource settings: A multi‐center evaluation of HemoTypeSC, a novel rapid test

American journal of hematology, 2019-01, Vol.94 (1), p.39-45

2019

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A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin

Molecular mechanisms of retroviral integration site selection

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74

Host and viral determinants for MxB restriction of HIV-1 infection

Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase–LEDGF/p75 interaction

Biochemical characterization of novel retroviral integrase proteins

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity

The Competitive Interplay between Allosteric HIV‑1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV‑1 Replication Adversely Affects Inhibitor Potency

Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration

Correction: Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration

A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication

Haematopoietic stem and progenitor cells from human pluripotent stem cells

Structural basis for retroviral integration into nucleosomes

Distinct viral reservoirs in individuals with spontaneous control of HIV-1

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

Implementation of a Sickle Cell Disease Screening Initiative in Uganda with HemoTypeSCTM

Fragment-Based Discovery of 8‑Hydroxyquinoline Inhibitors of the HIV‑1 Integrase–Lens Epithelium-Derived Growth Factor/p75 (IN–LEDGF/p75) Interaction

Sites of retroviral DNA integration: From basic research to clinical applications

Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites

HemoTypeSC Demonstrates >99% Field Accuracy in a Sickle Cell Disease Screening Initiative in Children of Southeastern Uganda

A supramolecular assembly mediates lentiviral DNA integration

Structural basis for spumavirus GAG tethering to chromatin

Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding

Point‐of‐care screening for sickle cell disease in low‐resource settings: A multi‐center evaluation of HemoTypeSC, a novel rapid test

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