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Rapid Synthesis of Aryl Fluorides in Continuous Flow through the Balz-Schiemann Reaction

Angewandte Chemie International Edition, 2016-09, Vol.55 (39), p.11907-11911

International ed. in English, 2016

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Enantioselective Total Synthesis of (+)-Amabiline

Organic letters, 2012-04, Vol.14 (7), p.1869-1871

2012

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Electrochemically Enabled Chan–Lam Couplings of Aryl Boronic Acids and Anilines

Organic letters, 2019-06, Vol.21 (12), p.4540-4543

2019

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High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein–Protein Interaction

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1543-1556

2014

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A Versatile Enantioselective Synthesis of Azabicyclic Ring Systems: A Concise Total Synthesis of (+)-Grandisine D and Unnatural Analogues

Chemistry : a European journal, 2012-05, Vol.18 (19), p.5826-5831

2012

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A general, enantioselective synthesis of N-alkyl terminal aziridines and C2-functionalized azetidines via organocatalysis

Tetrahedron letters, 2015-03, Vol.56 (10), p.1276-1279

2015

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A general, enantioselective synthesis of 1-azabicyclo[m.n.0]alkane ring systems

Tetrahedron letters, 2013-03, Vol.54 (13), p.1645-1648

2013

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Rapid Synthesis of Aryl Fluorides in Continuous Flow through the Balz-Schiemann Reaction

Angewandte Chemie, 2016-09, Vol.128 (39), p.12086-12090

2016

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Small Molecule APOL1 Channel Inhibitor Reduces Proteinuria, Rescues Podocyte Injury, and Reverses eGFR Decline in an APOL1-Mediated Kidney Disease Mouse Model: SA-PO701

Journal of the American Society of Nephrology, 2024-10, Vol.35 (10S)

2024

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Small Molecule Inhibition of APOL1 Channel Activity Protects Podocytes from Mitochondrial Dysfunction, Cell Death, and Barrier Disruption Induced by APOL1 Risk Variants: SA-PO700

Journal of the American Society of Nephrology, 2024-10, Vol.35 (10S)

2024

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APOL1 Inhibitors Reverse Established Proteinuria in an APOL1-Mediated Kidney Disease Mouse Model: TH-PO442

Journal of the American Society of Nephrology, 2022-11, Vol.33 (11S), p.169-169

2022

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A series of substituted isoindolinones as selective small molecule modulators of the Gβγ‐SNARE interaction

The FASEB journal, 2016-04, Vol.30 (S1)

2016

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A Versatile Enantioselective Synthesis of Azabicyclic Ring Systems: A Concise Total Synthesis of (+)-GrandisineD and Unnatural Analogues

Chemistry : a European journal, 2012-05, Vol.18 (19), p.5826-5831

2012

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High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein–Protein Interaction

Journal of medicinal chemistry, 2014-02, Vol.57 (4)

2014

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Abstract 2534: High-affinity small molecule inhibitors of the menin-MLL interaction reverse oncogenic transformation mediated by MLL fusion proteins in leukemia

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.2534-2534

2014

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A General and Stereoselective Approach for the Construction of Azabicyclic Compounds: Applications to the Synthesis of (+)-Amabiline and Grandisine D; Structure-based Design of Small Molecule Inhibitors of the Menin-MLL Protein-protein Interaction

Senter, Timothy J

2015

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ChemInform Abstract: A General, Enantioselective Synthesis of N-Alkyl Terminal Aziridines and C2-Functionalized Azetidines via Organocatalysis

ChemInform, 2015-06, Vol.46 (26), p.no-no

2015

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ChemInform Abstract: A General, Enantioselective Synthesis of 1-Azabicyclo[m.n.0]alkane Ring Systems

ChemInform, 2013-07, Vol.44 (28), p.no-no

2013

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Case Study 1: Scaffold Hopping for T‐Type Calcium Channel and Glycine Transporter Type 1 Inhibitors

Scaffold Hopping in Medicinal Chemistry, 2013, p.245-258

2013

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Lysosomal Trafficking and Cysteine Protease Metabolism Confer Target-specific Cytotoxicity by Peptide-linked Anti-CD30-Auristatin Conjugates

The Journal of biological chemistry, 2006-04, Vol.281 (15), p.10540-10547

2006

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Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants

Journal of clinical oncology, 2022-05, Vol.40 (14), p.1529-1541

2022

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Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

Cancer epidemiology, biomarkers & prevention, 2012-01, Vol.21 (1), p.134-147

2012

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Characterization of a new chronic lymphocytic leukemia cell line for mechanistic in vitro and in vivo studies relevant to disease

PloS one, 2013-10, Vol.8 (10), p.e76607

2013

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Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness

Cancer research (Chicago, Ill.), 2020-02, Vol.80 (3), p.624-638

2020

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Rapid Synthesis of Aryl Fluorides in Continuous Flow through the Balz-Schiemann Reaction

Enantioselective Total Synthesis of (+)-Amabiline

Electrochemically Enabled Chan–Lam Couplings of Aryl Boronic Acids and Anilines

High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein–Protein Interaction

Discovery and Optimization of Pyrazole Amides as Inhibitors of ELOVL1

A Versatile Enantioselective Synthesis of Azabicyclic Ring Systems: A Concise Total Synthesis of (+)-Grandisine D and Unnatural Analogues

A general, enantioselective synthesis of N-alkyl terminal aziridines and C2-functionalized azetidines via organocatalysis

A general, enantioselective synthesis of 1-azabicyclo[m.n.0]alkane ring systems

Rapid Synthesis of Aryl Fluorides in Continuous Flow through the Balz-Schiemann Reaction

Small Molecule APOL1 Channel Inhibitor Reduces Proteinuria, Rescues Podocyte Injury, and Reverses eGFR Decline in an APOL1-Mediated Kidney Disease Mouse Model: SA-PO701

Small Molecule Inhibition of APOL1 Channel Activity Protects Podocytes from Mitochondrial Dysfunction, Cell Death, and Barrier Disruption Induced by APOL1 Risk Variants: SA-PO700

APOL1 Inhibitors Reverse Established Proteinuria in an APOL1-Mediated Kidney Disease Mouse Model: TH-PO442

A series of substituted isoindolinones as selective small molecule modulators of the Gβγ‐SNARE interaction

A Versatile Enantioselective Synthesis of Azabicyclic Ring Systems: A Concise Total Synthesis of (+)-GrandisineD and Unnatural Analogues

High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein–Protein Interaction

Abstract 2534: High-affinity small molecule inhibitors of the menin-MLL interaction reverse oncogenic transformation mediated by MLL fusion proteins in leukemia

A General and Stereoselective Approach for the Construction of Azabicyclic Compounds: Applications to the Synthesis of (+)-Amabiline and Grandisine D; Structure-based Design of Small Molecule Inhibitors of the Menin-MLL Protein-protein Interaction

ChemInform Abstract: A General, Enantioselective Synthesis of N-Alkyl Terminal Aziridines and C2-Functionalized Azetidines via Organocatalysis

ChemInform Abstract: A General, Enantioselective Synthesis of 1-Azabicyclo[m.n.0]alkane Ring Systems

Case Study 1: Scaffold Hopping for T‐Type Calcium Channel and Glycine Transporter Type 1 Inhibitors

Lysosomal Trafficking and Cysteine Protease Metabolism Confer Target-specific Cytotoxicity by Peptide-linked Anti-CD30-Auristatin Conjugates

Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants

Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

Characterization of a new chronic lymphocytic leukemia cell line for mechanistic in vitro and in vivo studies relevant to disease

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness

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