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Src family kinases: at the forefront of platelet activation

Blood, 2014-09, Vol.124 (13), p.2013-2024

2014

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ITIM receptors: more than just inhibitors of platelet activation

Blood, 2017-06, Vol.129 (26), p.3407-3418

2017

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Global Proteomic Assessment of the Classical Protein-Tyrosine Phosphatome and “Redoxome”

Cell, 2011-09, Vol.146 (5), p.826-840

2011

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Targeting Receptor-Type Protein Tyrosine Phosphatases with Biotherapeutics: Is Outside-in Better than Inside-Out?

Molecules (Basel, Switzerland), 2018-03, Vol.23 (3), p.569

2018

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Collagen type I degradation fragments act through the collagen receptor LAIR-1 to provide a negative feedback for osteoclast formation

Bone (New York, N.Y.), 2018-12, Vol.117, p.23-30

2018

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Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function

Blood, 2013-05, Vol.121 (20), p.4205-4220

2013

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Megakaryocyte NLRP3 hyperactivation induces mild anemia and potentiates inflammatory response in mice

Frontiers in immunology, 2023-08, Vol.14, p.1226196

2023

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Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets

Arteriosclerosis, thrombosis, and vascular biology, 2017-05, Vol.37 (5), p.823-835

2017

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Lymphatic blood filling in CLEC-2-deficient mouse models

Platelets (Edinburgh), 2021-04, Vol.32 (3), p.352-367

2021

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Evaluation of the Total Thrombus-Formation System (T-TAS): application to human and mouse blood analysis

Platelets (Edinburgh), 2019-10, Vol.30 (7), p.893-900

2019

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Platelet Src family kinases: A tale of reversible phosphorylation

Research and practice in thrombosis and haemostasis, 2021-03, Vol.5 (3), p.376-389

2021

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The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis

Blood, 2009-05, Vol.113 (20), p.4942-4954

2009

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Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function

Science signaling, 2012-10, Vol.5 (248), p.ra78

2012

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LAIR-1 and PECAM-1 function via the same signaling pathway to inhibit GPVI-mediated platelet activation

Research and practice in thrombosis and haemostasis, 2024-08, Vol.8 (6), p.102557, Article 102557

2024

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TLT-1: please release me, let me go

Blood, 2018-12, Vol.132 (23), p.2427-2429

Senis, Yotis A.

2018

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TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice

Blood advances, 2018-08, Vol.2 (16), p.2072-2078

2018

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Enhanced BCR signaling inflicts early plasmablast and germinal center B cell death

iScience, 2021-02, Vol.24 (2), p.102038-102038, Article 102038

2021

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Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains

Biochemical journal, 2009-01, Vol.417 (1), p.391-401

2009

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Mouse tissue factor enzyme-linked immunosorbent assays: a sensitive issue

Research and practice in thrombosis and haemostasis, 2024-03, Vol.8 (3), p.102386-102386, Article 102386

Senis, Yotis A.

2024

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A Comprehensive Proteomics and Genomics Analysis Reveals Novel Transmembrane Proteins in Human Platelets and Mouse Megakaryocytes Including G6b-B, a Novel Immunoreceptor Tyrosine-based Inhibitory Motif Protein

Molecular & cellular proteomics, 2007-03, Vol.6 (3), p.548-564

2007

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G6b-B Inhibits Constitutive and Agonist-induced Signaling by Glycoprotein VI and CLEC-2

The Journal of biological chemistry, 2008-12, Vol.283 (51), p.35419-35427

2008

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Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets

Molecular cell, 2020-05, Vol.78 (3), p.477-492.e8

2020

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Alan Randolph Giles, MD (1940–2022): dogged pioneer and esteemed hematologist

Journal of thrombosis and haemostasis, 2023-02, Vol.21 (2), p.397-399

2023

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Interplay between the tyrosine kinases Chk and Csk and phosphatase PTPRJ is critical for regulating platelets in mice

Blood, 2020-04, Vol.135 (18), p.1574-1587

2020

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Src family kinases: at the forefront of platelet activation

ITIM receptors: more than just inhibitors of platelet activation

Global Proteomic Assessment of the Classical Protein-Tyrosine Phosphatome and “Redoxome”

Targeting Receptor-Type Protein Tyrosine Phosphatases with Biotherapeutics: Is Outside-in Better than Inside-Out?

Collagen type I degradation fragments act through the collagen receptor LAIR-1 to provide a negative feedback for osteoclast formation

Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function

Megakaryocyte NLRP3 hyperactivation induces mild anemia and potentiates inflammatory response in mice

Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets

Lymphatic blood filling in CLEC-2-deficient mouse models

Evaluation of the Total Thrombus-Formation System (T-TAS): application to human and mouse blood analysis

Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

Platelet Src family kinases: A tale of reversible phosphorylation

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis

Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function

LAIR-1 and PECAM-1 function via the same signaling pathway to inhibit GPVI-mediated platelet activation

TLT-1: please release me, let me go

TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice

Enhanced BCR signaling inflicts early plasmablast and germinal center B cell death

Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains

Mouse tissue factor enzyme-linked immunosorbent assays: a sensitive issue

A Comprehensive Proteomics and Genomics Analysis Reveals Novel Transmembrane Proteins in Human Platelets and Mouse Megakaryocytes Including G6b-B, a Novel Immunoreceptor Tyrosine-based Inhibitory Motif Protein

G6b-B Inhibits Constitutive and Agonist-induced Signaling by Glycoprotein VI and CLEC-2

Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets

Alan Randolph Giles, MD (1940–2022): dogged pioneer and esteemed hematologist

Interplay between the tyrosine kinases Chk and Csk and phosphatase PTPRJ is critical for regulating platelets in mice

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