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Amyloidosis: Pathogenesis and New Therapeutic Options

Journal of clinical oncology, 2011-05, Vol.29 (14), p.1924-1933

2011

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A phase 1/2 study of the oral proteasome inhibitor ixazomib in relapsed or refractory AL amyloidosis

Blood, 2017-08, Vol.130 (5), p.597-605

2017

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Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients

Blood, 2011-10, Vol.118 (16), p.4346-4352

2011

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Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish

American journal of physiology. Heart and circulatory physiology, 2013-07, Vol.305 (1), p.H95-H103

2013

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Amyloidosis of the gastrointestinal tract: a 13-year, single-center, referral experience

Haematologica (Roma), 2013-01, Vol.98 (1), p.141-146

2013

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Epithelial-to-Mesenchymal Transition Induced by TGF-β1 Is Mediated by Blimp-1―Dependent Repression of BMP-5

Cancer research (Chicago, Ill.), 2012-12, Vol.72 (23), p.6268-6278

2012

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Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis

Blood, 2011-12, Vol.118 (25), p.6610-6617

2011

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The Alpha Catalytic Subunit of Protein Kinase CK2 Is Required for Mouse Embryonic Development

Molecular and Cellular Biology, 2008-01, Vol.28 (1), p.131-139

2008

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Foxk1 recruits the Sds3 complex and represses gene expression in myogenic progenitors

Biochemical journal, 2012-09, Vol.446 (3), p.349-357

2012

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Cardiac amyloidosis in African Americans: Comparison of clinical and laboratory features of transthyretin V122I amyloidosis and immunoglobulin light chain amyloidosis

The American heart journal, 2009-10, Vol.158 (4), p.607-614

2009

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Lenalidomide and dexamethasone in the treatment of AL amyloidosis: results of a phase 2 trial

Blood, 2007-01, Vol.109 (2), p.492-496

2007

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Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain‐mediated cardiotoxicity

EMBO molecular medicine, 2014-11, Vol.6 (11), p.1493-1507

2014

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Melphalan, lenalidomide and dexamethasone for the treatment of immunoglobulin light chain amyloidosis: results of a phase II trial

Haematologica (Roma), 2013-05, Vol.98 (5), p.789-792

2013

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Predictors of survival to orthotopic heart transplant in patients with light chain amyloidosis

The Journal of heart and lung transplantation, 2014-02, Vol.33 (2), p.149-156

2014

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The multifaceted role of protein kinase CK2 in high-risk acute lymphoblastic leukemia

Haematologica (Roma), 2021-05, Vol.106 (5), p.1461-1465

2021

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The Critical Role of the Constant Region in Thermal Stability and Aggregation of Amyloidogenic Immunoglobulin Light Chain

Biochemistry (Easton), 2010-11, Vol.49 (45), p.9848-9857

2010

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Amyloidogenic and Associated Proteins in Systemic Amyloidosis Proteome of Adipose Tissue

Molecular & cellular proteomics, 2008-08, Vol.7 (8), p.1570-1583

2008

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Cooperative Stabilization of Transthyretin by Clusterin and Diflunisal

Biochemistry (Easton), 2015-01, Vol.54 (2), p.268-278

2015

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Heart Failure Resulting From Age-Related Cardiac Amyloid Disease Associated With Wild-Type Transthyretin: A Prospective, Observational Cohort Study

Circulation (New York, N.Y.), 2016-01, Vol.133 (3), p.282-290

2016

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CK2 inhibitor CX-4945 destabilizes NOTCH1 and synergizes with JQ1 against human T-acute lymphoblastic leukemic cells

Haematologica (Roma), 2017-01, Vol.102 (1), p.e17-e21

2017

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Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis

Oncogene, 2002-08, Vol.21 (34), p.5280-5288

2002

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Risk factors for venous thromboembolism in immunoglobulin light chain amyloidosis

Haematologica (Roma), 2016-01, Vol.101 (1), p.86-90

2016

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Evidence for a Functional Role of the Molecular Chaperone Clusterin in Amyloidotic Cardiomyopathy

The American journal of pathology, 2011, Vol.178 (1), p.61-68

2011

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Role of Glycosaminoglycan Sulfation in the Formation of Immunoglobulin Light Chain Amyloid Oligomers and Fibrils

The Journal of biological chemistry, 2010-11, Vol.285 (48), p.37672-37682

2010

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Direct identification of PTEN phosphorylation sites

FEBS letters, 2002-09, Vol.528 (1), p.145-153

2002

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Amyloidosis: Pathogenesis and New Therapeutic Options

A phase 1/2 study of the oral proteasome inhibitor ixazomib in relapsed or refractory AL amyloidosis

Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients

Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish

Amyloidosis of the gastrointestinal tract: a 13-year, single-center, referral experience

Epithelial-to-Mesenchymal Transition Induced by TGF-β1 Is Mediated by Blimp-1―Dependent Repression of BMP-5

Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis

The Alpha Catalytic Subunit of Protein Kinase CK2 Is Required for Mouse Embryonic Development

Foxk1 recruits the Sds3 complex and represses gene expression in myogenic progenitors

Cardiac amyloidosis in African Americans: Comparison of clinical and laboratory features of transthyretin V122I amyloidosis and immunoglobulin light chain amyloidosis

Lenalidomide and dexamethasone in the treatment of AL amyloidosis: results of a phase 2 trial

Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain‐mediated cardiotoxicity

Melphalan, lenalidomide and dexamethasone for the treatment of immunoglobulin light chain amyloidosis: results of a phase II trial

Predictors of survival to orthotopic heart transplant in patients with light chain amyloidosis

The multifaceted role of protein kinase CK2 in high-risk acute lymphoblastic leukemia

The Critical Role of the Constant Region in Thermal Stability and Aggregation of Amyloidogenic Immunoglobulin Light Chain

Amyloidogenic and Associated Proteins in Systemic Amyloidosis Proteome of Adipose Tissue

Cooperative Stabilization of Transthyretin by Clusterin and Diflunisal

Heart Failure Resulting From Age-Related Cardiac Amyloid Disease Associated With Wild-Type Transthyretin: A Prospective, Observational Cohort Study

CK2 inhibitor CX-4945 destabilizes NOTCH1 and synergizes with JQ1 against human T-acute lymphoblastic leukemic cells

Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis

Risk factors for venous thromboembolism in immunoglobulin light chain amyloidosis

Evidence for a Functional Role of the Molecular Chaperone Clusterin in Amyloidotic Cardiomyopathy

Role of Glycosaminoglycan Sulfation in the Formation of Immunoglobulin Light Chain Amyloid Oligomers and Fibrils

Direct identification of PTEN phosphorylation sites

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