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ent -Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2 -/- Mice

Molecular pharmacology, 2024-03, Vol.105 (3), p.194-201

2024

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Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening

The Journal of biological chemistry, 2022-01, Vol.298 (1), p.101412-101412, Article 101412

2022

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RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET

ACS chemical biology, 2023-10, Vol.18 (10), p.2290-2299

2023

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The Future of Boron in Medicinal Chemistry: Therapeutic and Diagnostic Applications

Atypical Elements in Drug Design, 2016, Vol.17, p.1-27

2016

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Selenium-Based Drug Design

Atypical Elements in Drug Design, 2016, Vol.17, p.87-118

2016

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Silicon Mimics of Unstable Carbon

Atypical Elements in Drug Design, 2016, Vol.17, p.61-85

2016

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Insight into the therapeutic potential of ent-verticilide based on direct measures of RyR function

Biophysical journal, 2022-02, Vol.121 (3), p.377a-377a

2022

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Understanding calmodulin regulation of RyR1 through steady state and stopped-flow fluorescence detection of Ca2+ binding kinetics to calmodulin bound to purified full-length RyR1

Biophysical journal, 2022-02, Vol.121 (3), p.379a-380a

2022

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Selenium-Functionalized Molecules (SeFMs) as Potential Drugs and Nutritional Supplements

Atypical Elements in Drug Design, 2016, Vol.17, p.119-153

2016

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High-Throughput Screening Yields Allosteric Inhibitors of Leaky RyRs for Therapeutic Development

Biophysical journal, 2020-02, Vol.118 (3), p.568a-568a

2020

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Macromolecular Crowding Effects on the Excited-state Dynamics of Novel FRET Probes Using Time-resolved Fluorescence

Schwarz, Jacob A

2017

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Drug Design Based on the Carbon/Silicon Switch Strategy

Atypical Elements in Drug Design, 2016, Vol.17, p.29-59

2016

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Intro

Atypical Elements in Drug Design, 2016, Vol.17

Schwarz, Jacob

2016

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Announcing the Latest Inductees to the ACS Division of Medicinal Chemistry Hall of Fame

Journal of medicinal chemistry, 2021-08, Vol.64 (15), p.10517-10518

Schwarz, Jacob B.

2021

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Highlighting the 2020–2021 ACS Division of Medicinal Chemistry Award Winners

Journal of medicinal chemistry, 2022-09, Vol.65 (18), p.11891-11893

2022

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Optimized arylomycins are a new class of Gram-negative antibiotics

Nature (London), 2018-09, Vol.561 (7722), p.189-194

2018

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Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin

Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (12), p.E690-E697

2012

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Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function

Neuron (Cambridge, Mass.), 2016-03, Vol.89 (5), p.983-999

2016

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Global budget and radiative forcing of black carbon aerosol: Constraints from pole-to-pole (HIPPO) observations across the Pacific

Journal of geophysical research. Atmospheres, 2014-01, Vol.119 (1), p.195-206

2014

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1160: EOSINOPHILIC PNEUMONIA ASSOCIATED WITH LION’S MANE SUPPLEMENTATION

Critical care medicine, 2024-01, Vol.52 (1), p.S552-S552

2024

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Sources, seasonality, and trends of southeast US aerosol: an integrated analysis of surface, aircraft, and satellite observations with the GEOS-Chem chemical transport model

Atmospheric chemistry and physics, 2015-09, Vol.15 (18), p.10411-10433

2015

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Deep intronic mutation in OFD1, identified by targeted genomic next-generation sequencing, causes a severe form of X-linked retinitis pigmentosa (RP23)

Human molecular genetics, 2012-08, Vol.21 (16), p.3647-3654

2012

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Visible-Light-Driven Water Oxidation by a Molecular Manganese Vanadium Oxide Cluster

Angewandte Chemie (International ed.), 2016-05, Vol.55 (21), p.6329-6333

International ed. in English, 2016

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Perioperative prophylactic middle meningeal artery embolization for chronic subdural hematoma: a series of 44 cases

Journal of neurosurgery, 2021-12, Vol.135 (6), p.1627-1635

2021

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The Philip S. Portoghese Journal of Medicinal Chemistry/Division of Medicinal Chemistry Joint Lectureship Awards

Journal of medicinal chemistry, 2021-03, Vol.64 (5), p.2311-2311

2021

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ent -Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2 -/- Mice

Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening

RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET

The Future of Boron in Medicinal Chemistry: Therapeutic and Diagnostic Applications

Selenium-Based Drug Design

Silicon Mimics of Unstable Carbon

Insight into the therapeutic potential of ent-verticilide based on direct measures of RyR function

Understanding calmodulin regulation of RyR1 through steady state and stopped-flow fluorescence detection of Ca2+ binding kinetics to calmodulin bound to purified full-length RyR1

Selenium-Functionalized Molecules (SeFMs) as Potential Drugs and Nutritional Supplements

High-Throughput Screening Yields Allosteric Inhibitors of Leaky RyRs for Therapeutic Development

Macromolecular Crowding Effects on the Excited-state Dynamics of Novel FRET Probes Using Time-resolved Fluorescence

Drug Design Based on the Carbon/Silicon Switch Strategy

Intro

Announcing the Latest Inductees to the ACS Division of Medicinal Chemistry Hall of Fame

Highlighting the 2020–2021 ACS Division of Medicinal Chemistry Award Winners

Optimized arylomycins are a new class of Gram-negative antibiotics

Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function

Global budget and radiative forcing of black carbon aerosol: Constraints from pole-to-pole (HIPPO) observations across the Pacific

1160: EOSINOPHILIC PNEUMONIA ASSOCIATED WITH LION’S MANE SUPPLEMENTATION

Sources, seasonality, and trends of southeast US aerosol: an integrated analysis of surface, aircraft, and satellite observations with the GEOS-Chem chemical transport model

Deep intronic mutation in OFD1, identified by targeted genomic next-generation sequencing, causes a severe form of X-linked retinitis pigmentosa (RP23)

Visible-Light-Driven Water Oxidation by a Molecular Manganese Vanadium Oxide Cluster

Perioperative prophylactic middle meningeal artery embolization for chronic subdural hematoma: a series of 44 cases

The Philip S. Portoghese Journal of Medicinal Chemistry/Division of Medicinal Chemistry Joint Lectureship Awards

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