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Some Examples of Bacterial Toxins as Tools

Toxins, 2024-05, Vol.16 (5), p.202

Schmidt, Gudula

2024

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Genome wide CRISPR screen for Pasteurella multocida toxin (PMT) binding proteins reveals LDL Receptor Related Protein 1 (LRP1) as crucial cellular receptor

PLoS pathogens, 2022-12, Vol.18 (12), p.e1010781

2022

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Bacterial Toxins for Cancer Therapy

Toxins, 2017-07, Vol.9 (8), p.236

2017

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RhoA/C inhibits proliferation by inducing the synthesis of GPRC5A

Scientific reports, 2020-07, Vol.10 (1), p.12532-11, Article 12532

2020

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From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract

PloS one, 2014-01, Vol.9 (1), p.e86147

2014

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CTX-CNF1 Recombinant Protein Selectively Targets Glioma Cells In Vivo

Toxins, 2021-03, Vol.13 (3), p.194

2021

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Lu/BCAM adhesion glycoprotein is a receptor for Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1)

PLoS pathogens, 2014-01, Vol.10 (1), p.e1003884

2014

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IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation

The EMBO journal, 2012-01, Vol.31 (1), p.14-28

2012

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RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

Molecular biology of the cell, 2011-03, Vol.22 (5), p.593-605

2011

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Specific role of RhoC in tumor invasion and metastasis

Oncotarget, 2017-10, Vol.8 (50), p.87364-87378

2017

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Tenascin C and tenascin R similarly prevent the formation of myelin membranes in a RhoA-dependent manner, but antagonistically regulate the expression of myelin basic protein via a separate pathway

Glia, 2009-12, Vol.57 (16), p.1790-1801

2009

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Inhibition of Rho A activity causes pemphigus skin blistering

The Journal of cell biology, 2006-12, Vol.175 (5), p.721-727

2006

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Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathway

Journal of cell science, 2010-06, Vol.123 (11), p.1948-1958

2010

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Cleavage of Escherichia coli Cytotoxic Necrotizing Factor 1 Is Required for Full Biologic Activity

Infection and Immunity, 2009-05, Vol.77 (5), p.1835-1841

2009

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High Affinity Binding of Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1) to Lu/BCAM Adhesion Glycoprotein

Toxins, 2017-12, Vol.10 (1), p.3

2017

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Cytotoxic Necrotizing Factors (CNFs)-A Growing Toxin Family

Toxins, 2010-01, Vol.2 (1), p.116-127

2010

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Loss of LSR affects epithelial barrier integrity and tumor xenograft growth of CaCo-2 cells

Oncotarget, 2017-06, Vol.8 (23), p.37009-37022

2017

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Involvement of Osteocytes in the Action of Pasteurella multocida Toxin

Toxins, 2018-08, Vol.10 (8), p.328

2018

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Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase cascade via the Gα(q/11)--p63RhoGEF--RhoA axis

PLoS pathogens, 2013, Vol.9 (5), p.e1003385-e1003385

2013

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Role of the small Rho GTPases Rac1 and Cdc42 in host cell invasion of Campylobacter jejuni

Cellular microbiology, 2007-10, Vol.9 (10), p.2431-2444

2007

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Cytotoxic Necrotizing Factors from Yersinia pseudotuberculosis and from Escherichia coli Bind to Different Cellular Receptors but Take the Same Route to the Cytosol

Infection and Immunity, 2007-07, Vol.75 (7), p.3344-3353

2007

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Toxin-induced RhoA Activity Mediates CCL1-triggered Signal Transducers and Activators of Transcription Protein Signaling

The Journal of biological chemistry, 2012-03, Vol.287 (14), p.11183-11194

2012

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Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1

Nature (London), 1997-06, Vol.387 (6634), p.725-729

1997

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Targeting of the actin cytoskeleton by insecticidal toxins from Photorhabdus luminescens

Naunyn-Schmiedeberg's archives of pharmacology, 2011-03, Vol.383 (3), p.227-235

2011

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GAP activity of the Yersinia YopE cytotoxin specifically targets the Rho pathway: a mechanism for disruption of actin microfilament structure

Molecular microbiology, 2000-05, Vol.36 (3), p.737-748

2000

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Some Examples of Bacterial Toxins as Tools

Genome wide CRISPR screen for Pasteurella multocida toxin (PMT) binding proteins reveals LDL Receptor Related Protein 1 (LRP1) as crucial cellular receptor

Bacterial Toxins for Cancer Therapy

RhoA/C inhibits proliferation by inducing the synthesis of GPRC5A

From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract

CTX-CNF1 Recombinant Protein Selectively Targets Glioma Cells In Vivo

Lu/BCAM adhesion glycoprotein is a receptor for Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1)

IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation

RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

Specific role of RhoC in tumor invasion and metastasis

Tenascin C and tenascin R similarly prevent the formation of myelin membranes in a RhoA-dependent manner, but antagonistically regulate the expression of myelin basic protein via a separate pathway

Inhibition of Rho A activity causes pemphigus skin blistering

Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathway

Cleavage of Escherichia coli Cytotoxic Necrotizing Factor 1 Is Required for Full Biologic Activity

High Affinity Binding of Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1) to Lu/BCAM Adhesion Glycoprotein

Cytotoxic Necrotizing Factors (CNFs)-A Growing Toxin Family

Loss of LSR affects epithelial barrier integrity and tumor xenograft growth of CaCo-2 cells

Involvement of Osteocytes in the Action of Pasteurella multocida Toxin

Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase cascade via the Gα(q/11)--p63RhoGEF--RhoA axis

Role of the small Rho GTPases Rac1 and Cdc42 in host cell invasion of Campylobacter jejuni

Cytotoxic Necrotizing Factors from Yersinia pseudotuberculosis and from Escherichia coli Bind to Different Cellular Receptors but Take the Same Route to the Cytosol

Toxin-induced RhoA Activity Mediates CCL1-triggered Signal Transducers and Activators of Transcription Protein Signaling

Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1

Targeting of the actin cytoskeleton by insecticidal toxins from Photorhabdus luminescens

GAP activity of the Yersinia YopE cytotoxin specifically targets the Rho pathway: a mechanism for disruption of actin microfilament structure

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