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Expanding the Chemical Space of Synthetic Cyclic Peptides Using a Promiscuous Macrocyclase from Prenylagaramide Biosynthesis

ACS catalysis, 2020-07, Vol.10 (13), p.7146-7153

2020

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Metagenomic discovery of polybrominated diphenyl ether biosynthesis by marine sponges

Nature chemical biology, 2017-05, Vol.13 (5), p.537

2017

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The polyketide to fatty acid transition in the evolution of animal lipid metabolism

Nature communications, 2024-01, Vol.15 (1), p.236-236, Article 236

2024

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Translating Marine Symbioses toward Drug Development

mBio, 2022-12, Vol.13 (6), p.e0249922-e0249922

2022

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Trading molecules and tracking targets in symbiotic interactions

Nature chemical biology, 2008-08, Vol.4 (8), p.466-473

Schmidt, Eric W

2008

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Genome‐Mining‐Based Discovery of the Cyclic Peptide Tolypamide and TolF, a Ser/Thr Forward O‐Prenyltransferase

Angewandte Chemie (International ed.), 2021-04, Vol.60 (15), p.8460-8465

International ed. in English, 2021

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The Biochemistry and Structural Biology of Cyanobactin Pathways: Enabling Combinatorial Biosynthesis

Methods in enzymology, 2018, Vol.604, p.113-163

2018

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Roads to Rome: Role of Multiple Cassettes in Cyanobactin RiPP Biosynthesis

Journal of the American Chemical Society, 2018-11, Vol.140 (47), p.16213-16221

2018

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Animal biosynthesis of complex polyketides in a photosynthetic partnership

Nature communications, 2020-06, Vol.11 (1), p.2882-2882, Article 2882

2020

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Enzymatic N- and C‑Protection in Cyanobactin RiPP Natural Products

Journal of the American Chemical Society, 2017-03, Vol.139 (8), p.2884-2887

2017

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Genome streamlining and chemical defense in a coral reef symbiosis

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (50), p.20655-20660

2012

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A Single Amino Acid Switch Alters the Isoprene Donor Specificity in Ribosomally Synthesized and Post-Translationally Modified Peptide Prenyltransferases

Journal of the American Chemical Society, 2018-07, Vol.140 (26), p.8124-8127

2018

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Combinatorialization of Fungal Polyketide Synthase–Peptide Synthetase Hybrid Proteins

Journal of the American Chemical Society, 2014-12, Vol.136 (51), p.17882-17890

2014

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Pyrrolocin C and equisetin inhibit bacterial acetyl-CoA carboxylase

PloS one, 2020-05, Vol.15 (5), p.e0233485

2020

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Enzymatic Basis of Ribosomal Peptide Prenylation in Cyanobacteria

Journal of the American Chemical Society, 2011-08, Vol.133 (34), p.13698-13705

2011

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Bacterial endosymbiosis in a chordate host: long-term co-evolution and conservation of secondary metabolism

PloS one, 2013-12, Vol.8 (12), p.e80822

2013

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Post-Translational Tyrosine Geranylation in Cyanobactin Biosynthesis

Journal of the American Chemical Society, 2018-05, Vol.140 (19), p.6044-6048

2018

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Molecular basis for the broad substrate selectivity of a peptide prenyltransferase

Proceedings of the National Academy of Sciences - PNAS, 2016-12, Vol.113 (49), p.14037-14042

2016

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Secondary Metabolites of the Genus Didemnum : A Comprehensive Review of Chemical Diversity and Pharmacological Properties

Marine drugs, 2020-06, Vol.18 (6), p.307

2020

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Biosynthesis of the Tetramic Acids Sch210971 and Sch210972

Organic letters, 2015-05, Vol.17 (10), p.2295-2297

2015

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A symbiotic bacterium of shipworms produces a compound with broad spectrum anti-apicomplexan activity

PLoS pathogens, 2020-05, Vol.16 (5), p.e1008600-e1008600

2020

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Patellamide A and C Biosynthesis by a Microcin-Like Pathway in Prochloron didemni, the Cyanobacterial Symbiont of Lissoclinum patella

Proceedings of the National Academy of Sciences - PNAS, 2005-05, Vol.102 (20), p.7315-7320

2005

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Variation in tropical reef symbiont metagenomes defined by secondary metabolism

PloS one, 2011-03, Vol.6 (3), p.e17897-e17897

2011

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Two Related Pyrrolidinedione Synthetase Loci in Fusarium heterosporum ATCC 74349 Produce Divergent Metabolites

ACS chemical biology, 2013-07, Vol.8 (7), p.1549-1557

2013

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Ribosomal Route to Small-Molecule Diversity

Journal of the American Chemical Society, 2012-01, Vol.134 (1), p.418-425

2012

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Expanding the Chemical Space of Synthetic Cyclic Peptides Using a Promiscuous Macrocyclase from Prenylagaramide Biosynthesis

Metagenomic discovery of polybrominated diphenyl ether biosynthesis by marine sponges

The polyketide to fatty acid transition in the evolution of animal lipid metabolism

Translating Marine Symbioses toward Drug Development

Trading molecules and tracking targets in symbiotic interactions

Genome‐Mining‐Based Discovery of the Cyclic Peptide Tolypamide and TolF, a Ser/Thr Forward O‐Prenyltransferase

The Biochemistry and Structural Biology of Cyanobactin Pathways: Enabling Combinatorial Biosynthesis

Roads to Rome: Role of Multiple Cassettes in Cyanobactin RiPP Biosynthesis

Animal biosynthesis of complex polyketides in a photosynthetic partnership

Enzymatic N- and C‑Protection in Cyanobactin RiPP Natural Products

Genome streamlining and chemical defense in a coral reef symbiosis

A Single Amino Acid Switch Alters the Isoprene Donor Specificity in Ribosomally Synthesized and Post-Translationally Modified Peptide Prenyltransferases

Combinatorialization of Fungal Polyketide Synthase–Peptide Synthetase Hybrid Proteins

Pyrrolocin C and equisetin inhibit bacterial acetyl-CoA carboxylase

Enzymatic Basis of Ribosomal Peptide Prenylation in Cyanobacteria

Bacterial endosymbiosis in a chordate host: long-term co-evolution and conservation of secondary metabolism

Post-Translational Tyrosine Geranylation in Cyanobactin Biosynthesis

Molecular basis for the broad substrate selectivity of a peptide prenyltransferase

Secondary Metabolites of the Genus Didemnum : A Comprehensive Review of Chemical Diversity and Pharmacological Properties

Biosynthesis of the Tetramic Acids Sch210971 and Sch210972

A symbiotic bacterium of shipworms produces a compound with broad spectrum anti-apicomplexan activity

Patellamide A and C Biosynthesis by a Microcin-Like Pathway in Prochloron didemni, the Cyanobacterial Symbiont of Lissoclinum patella

Variation in tropical reef symbiont metagenomes defined by secondary metabolism

Two Related Pyrrolidinedione Synthetase Loci in Fusarium heterosporum ATCC 74349 Produce Divergent Metabolites

Ribosomal Route to Small-Molecule Diversity

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