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Receptor tyrosine kinases: legacy of the first two decades

Cold Spring Harbor perspectives in biology, 2014-03, Vol.6 (3), p.a008912-a008912

Schlessinger, Joseph

2014

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Cellular signaling by fibroblast growth factor receptors

Cytokine & growth factor reviews, 2005-04, Vol.16 (2), p.139-149

2005

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A dormant TIL phenotype defines non-small cell lung carcinomas sensitive to immune checkpoint blockers

Nature communications, 2018-08, Vol.9 (1), p.3196-15, Article 3196

2018

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Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up

Annals of oncology, 2017-01, Vol.28 (1), p.75-82

2017

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Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor

Cell, 2007-07, Vol.130 (2), p.323-334

2007

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Mutation profiles in early-stage lung squamous cell carcinoma with clinical follow-up and correlation with markers of immune function

Annals of oncology, 2017-01, Vol.28 (1), p.83-89

2017

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Pyk2 Regulates Multiple Signaling Events Crucial for Macrophage Morphology and Migration

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (19), p.10740-10745

2003

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Cell Signaling by Receptor Tyrosine Kinases

Cell, 2000-10, Vol.103 (2), p.211-225

Schlessinger, Joseph

2000

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A randomized, placebo- and active-controlled, parallel-group, multicentre, investigator-blinded study of four treatment regimens of posaconazole in adults with toenail onychomycosis

British journal of dermatology (1951), 2012-02, Vol.166 (2), p.389-398

2012

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Critical Role for the Docking-Protein FRS2α in FGF Receptor-Mediated Signal Transduction Pathways

Proceedings of the National Academy of Sciences - PNAS, 2001-07, Vol.98 (15), p.8578-8583

2001

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Attenuation of Signaling Pathways Stimulated by Pathologically Activated FGF-Receptor 2 Mutants Prevents Craniosynostosis

Proceedings of the National Academy of Sciences - PNAS, 2006-12, Vol.103 (49), p.18603-18608

2006

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Growth factor signaling by receptor tyrosine kinases

Neuron, 1992-09, Vol.9 (3), p.383-391

1992

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A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design

Nature biotechnology, 2005-02, Vol.23 (2), p.201-207

2005

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Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up

Annals of oncology, 2018-04, Vol.29 (4), p.1072-1072

2018

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Stimulation of Phosphatidylinositol 3-Kinase by Fibroblast Growth Factor Receptors is Mediated by Coordinated Recruitment of Multiple Docking Proteins

Proceedings of the National Academy of Sciences - PNAS, 2001-05, Vol.98 (11), p.6074-6079

2001

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Ligand-Induced, Receptor-Mediated Dimerization and Activation of EGF Receptor

Cell, 2002-09, Vol.110 (6), p.669-672

Schlessinger, Joseph

2002

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Common and Distinct Elements in Cellular Signaling via EGF and FGF Receptors

Science (American Association for the Advancement of Science), 2004-11, Vol.306 (5701), p.1506-1507

Schlessinger, Joseph

2004

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Insights into the Molecular Basis for Fibroblast Growth Factor Receptor Autoinhibition and Ligand-Binding Promiscuity

Proceedings of the National Academy of Sciences - PNAS, 2004-01, Vol.101 (4), p.935-940

2004

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FRS2 Proteins Recruit Intracellular Signaling Pathways by Binding to Diverse Targets on Fibroblast Growth Factor and Nerve Growth Factor Receptors

Molecular and Cellular Biology, 2000-02, Vol.20 (3), p.979-989

2000

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Binding of Shp2 Tyrosine Phosphatase to FRS2 Is Essential for Fibroblast Growth Factor-Induced PC12 Cell Differentiation

Molecular and Cellular Biology, 1998-07, Vol.18 (7), p.3966-3973

1998

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Tyrosine Phosphorylation Sites on FRS2α Responsible for Shp2 Recruitment Are Critical for Induction of Lens and Retina

Proceedings of the National Academy of Sciences - PNAS, 2004-12, Vol.101 (49), p.17144-17149

2004

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A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

Nature (London), 1996-10, Vol.383 (6600), p.547-550

1996

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Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

Nature (London), 1995-08, Vol.376 (6543), p.737-745

1995

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407 Structural basis for inhibition of ligand-dependent and -independent ErbB3 activation by KTN3379

European journal of cancer (1990), 2014-11, Vol.50, p.130-130

2014

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A Lipid-Anchored Grb2-Binding Protein That Links FGF-Receptor Activation to the Ras/MAPK Signaling Pathway

Cell, 1997-05, Vol.89 (5), p.693-702

1997

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Receptor tyrosine kinases: legacy of the first two decades

Cellular signaling by fibroblast growth factor receptors

A dormant TIL phenotype defines non-small cell lung carcinomas sensitive to immune checkpoint blockers

Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up

Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor

Mutation profiles in early-stage lung squamous cell carcinoma with clinical follow-up and correlation with markers of immune function

Pyk2 Regulates Multiple Signaling Events Crucial for Macrophage Morphology and Migration

Cell Signaling by Receptor Tyrosine Kinases

A randomized, placebo- and active-controlled, parallel-group, multicentre, investigator-blinded study of four treatment regimens of posaconazole in adults with toenail onychomycosis

Critical Role for the Docking-Protein FRS2α in FGF Receptor-Mediated Signal Transduction Pathways

Attenuation of Signaling Pathways Stimulated by Pathologically Activated FGF-Receptor 2 Mutants Prevents Craniosynostosis

Growth factor signaling by receptor tyrosine kinases

A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design

Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up

Stimulation of Phosphatidylinositol 3-Kinase by Fibroblast Growth Factor Receptors is Mediated by Coordinated Recruitment of Multiple Docking Proteins

Ligand-Induced, Receptor-Mediated Dimerization and Activation of EGF Receptor

Common and Distinct Elements in Cellular Signaling via EGF and FGF Receptors

Insights into the Molecular Basis for Fibroblast Growth Factor Receptor Autoinhibition and Ligand-Binding Promiscuity

FRS2 Proteins Recruit Intracellular Signaling Pathways by Binding to Diverse Targets on Fibroblast Growth Factor and Nerve Growth Factor Receptors

Binding of Shp2 Tyrosine Phosphatase to FRS2 Is Essential for Fibroblast Growth Factor-Induced PC12 Cell Differentiation

Tyrosine Phosphorylation Sites on FRS2α Responsible for Shp2 Recruitment Are Critical for Induction of Lens and Retina

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

407 Structural basis for inhibition of ligand-dependent and -independent ErbB3 activation by KTN3379

A Lipid-Anchored Grb2-Binding Protein That Links FGF-Receptor Activation to the Ras/MAPK Signaling Pathway

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