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Identification and characterization of novel small-molecule protease-activated receptor 2 agonists

The Journal of pharmacology and experimental therapeutics, 2008-12, Vol.327 (3), p.799

2008

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Characterization of the Mas‐related gene family: structural and functional conservation of human and rhesus MrgX receptors

British journal of pharmacology, 2006-01, Vol.147 (1), p.73-82

2006

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Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist

European journal of pharmacology, 2008-08, Vol.590 (1), p.423-429

2008

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First-Time Disclosure of CVN424, a Potent and Selective GPR6 Inverse Agonist for the Treatment of Parkinson’s Disease: Discovery, Pharmacological Validation, and Identification of a Clinical Candidate

Journal of medicinal chemistry, 2021-07, Vol.64 (14), p.9875-9890

2021

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Development of CVN424: A Selective and Novel GPR6 Inverse Agonist Effective in Models of Parkinson Disease

The Journal of pharmacology and experimental therapeutics, 2021-06, Vol.377 (3), p.407

2021

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Discovery of TAK-041: a Potent and Selective GPR139 Agonist Explored for the Treatment of Negative Symptoms Associated with Schizophrenia

Journal of medicinal chemistry, 2021-08, Vol.64 (15), p.11527-11542

2021

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Monitoring Interactions between Receptor Tyrosine Kinases and Their Downstream Effector Proteins in Living Cells Using Bioluminescence Resonance Energy Transfer

Molecular pharmacology, 2007-12, Vol.72 (6), p.1440-1446

2007

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Pharmacology and Signaling Properties of Epidermal Growth Factor Receptor Isoforms Studied by Bioluminescence Resonance Energy Transfer

Molecular pharmacology, 2007-02, Vol.71 (2), p.508-518

2007

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Identification of the Atypical L-Type Ca2+ Channel Blocker Diltiazem and Its Metabolites As Ghrelin Receptor Agonists

Molecular pharmacology, 2007-08, Vol.72 (2), p.380-386

2007

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II. In vitro evidence that (−)-OSU6162 and (+)-OSU6162 produce their behavioral effects through 5-HT2A serotonin and D2 dopamine receptors

JOURNAL OF NEURAL TRANSMISSION, 2011-11, Vol.118 (11), p.1523-1533

2011

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Rat GluR7 and a Carboxy-Terminal Splice Variant, GluR7b, Are Functional Kainate Receptor Subunits with a Low Sensitivity to Glutamate

Neuron (Cambridge, Mass.), 1997-11, Vol.19 (5), p.1141-1146

1997

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Glutamate receptor genes: susceptibility factors in schizophrenia and depressive disorders?

Molecular neurobiology, 2002-04, Vol.25 (2), p.191-212

Schiffer, Hans H

2002

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The human angiotensin AT(1) receptor supports G protein-independent extracellular signal-regulated kinase 1/2 activation and cellular proliferation

European journal of pharmacology, 2008-08, Vol.590 (1-3), p.255

2008

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The human angiotensin AT1 receptor supports G protein-independent extracellular signal-regulated kinase 1/2 activation and cellular proliferation

European journal of pharmacology, 2008-08, Vol.590 (1-3), p.255-263

2008

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Integrative functional assays, chemical genomics and high throughput screening: harnessing signal transduction pathways to a common HTS readout

Current pharmaceutical design, 2006-05, Vol.12 (14), p.1717

2006

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Pharmacological characterization of AC-262536, a novel selective androgen receptor modulator

The Journal of steroid biochemistry and molecular biology, 2008-03, Vol.109 (1), p.129-137

2008

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Identification of CVN058, a Novel Brain Penetrant, Selective 5-HT3 Receptor Antagonist That Shows Efficacy in Pre-Clinical Cognition Models

Biological psychiatry (1969), 2021-05, Vol.89 (9), p.S26-S26

2021

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Differential regulation of muscarinic M1 receptors by orthosteric and allosteric ligands

BMC pharmacology, 2009-12, Vol.9 (1), p.14-14, Article 14

2009

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Pharmacology of polymorphic variants of the human 5-HT1A receptor

Biochemical pharmacology, 2004-02, Vol.67 (3), p.479-490

2004

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Generation and Analysis of GluR5(Q636R) Kainate Receptor Mutant Mice

The Journal of neuroscience, 1999-10, Vol.19 (20), p.8757-8764

1999

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Unequal Expression of Allelic Kainate Receptor GluR7 mRNAs in Human Brains

The Journal of neuroscience, 2000-12, Vol.20 (24), p.9025-9033

2000

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Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist

The Journal of pharmacology and experimental therapeutics, 2006-05, Vol.317 (2), p.910

2006

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AC-260584, an orally bioavailable M1 muscarinic receptor allosteric agonist, improves cognitive performance in an animal model

Neuropharmacology, 2010-02, Vol.58 (2), p.365-373

2010

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AC-260584, an orally bioavailable M 1 muscarinic receptor allosteric agonist, improves cognitive performance in an animal model

Neuropharmacology, 2010-02, Vol.58 (2), p.365-373

2010

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Glutamate Receptor Genes

Molecular neurobiology, 2002, Vol.25 (2), p.191-212

Schiffer, Hans H.

2002

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Identification and characterization of novel small-molecule protease-activated receptor 2 agonists

Characterization of the Mas‐related gene family: structural and functional conservation of human and rhesus MrgX receptors

Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist

First-Time Disclosure of CVN424, a Potent and Selective GPR6 Inverse Agonist for the Treatment of Parkinson’s Disease: Discovery, Pharmacological Validation, and Identification of a Clinical Candidate

Development of CVN424: A Selective and Novel GPR6 Inverse Agonist Effective in Models of Parkinson Disease

Discovery of TAK-041: a Potent and Selective GPR139 Agonist Explored for the Treatment of Negative Symptoms Associated with Schizophrenia

Monitoring Interactions between Receptor Tyrosine Kinases and Their Downstream Effector Proteins in Living Cells Using Bioluminescence Resonance Energy Transfer

Pharmacology and Signaling Properties of Epidermal Growth Factor Receptor Isoforms Studied by Bioluminescence Resonance Energy Transfer

Identification of the Atypical L-Type Ca2+ Channel Blocker Diltiazem and Its Metabolites As Ghrelin Receptor Agonists

II. In vitro evidence that (−)-OSU6162 and (+)-OSU6162 produce their behavioral effects through 5-HT2A serotonin and D2 dopamine receptors

Rat GluR7 and a Carboxy-Terminal Splice Variant, GluR7b, Are Functional Kainate Receptor Subunits with a Low Sensitivity to Glutamate

Glutamate receptor genes: susceptibility factors in schizophrenia and depressive disorders?

The human angiotensin AT(1) receptor supports G protein-independent extracellular signal-regulated kinase 1/2 activation and cellular proliferation

The human angiotensin AT1 receptor supports G protein-independent extracellular signal-regulated kinase 1/2 activation and cellular proliferation

Integrative functional assays, chemical genomics and high throughput screening: harnessing signal transduction pathways to a common HTS readout

Pharmacological characterization of AC-262536, a novel selective androgen receptor modulator

Identification of CVN058, a Novel Brain Penetrant, Selective 5-HT3 Receptor Antagonist That Shows Efficacy in Pre-Clinical Cognition Models

Differential regulation of muscarinic M1 receptors by orthosteric and allosteric ligands

Pharmacology of polymorphic variants of the human 5-HT1A receptor

Generation and Analysis of GluR5(Q636R) Kainate Receptor Mutant Mice

Unequal Expression of Allelic Kainate Receptor GluR7 mRNAs in Human Brains

Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist

AC-260584, an orally bioavailable M1 muscarinic receptor allosteric agonist, improves cognitive performance in an animal model

AC-260584, an orally bioavailable M 1 muscarinic receptor allosteric agonist, improves cognitive performance in an animal model

Glutamate Receptor Genes

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