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Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

Cell, 2013-03, Vol.153 (1), p.126-138

2013

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Antibodies in HIV-1 Vaccine Development and Therapy

Science (American Association for the Advancement of Science), 2013-09, Vol.341 (6151), p.1199-1204

2013

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Structural Insights on the Role of Antibodies in HIV-1 Vaccine and Therapy

Cell, 2014-02, Vol.156 (4), p.633-648

2014

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Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

Science (American Association for the Advancement of Science), 2010-08, Vol.329 (5993), p.811-817

2010

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Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (47), p.19059-19060

2012

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Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies

The Journal of experimental medicine, 2013-04, Vol.210 (4), p.655-663

2013

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Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike

Cell reports (Cambridge), 2014-05, Vol.7 (3), p.785-795

2014

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HIV therapy by a combination of broadly neutralizing antibodies in humanized mice

Nature (London), 2012-12, Vol.492 (7427), p.118-122

2012

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Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design

Science (American Association for the Advancement of Science), 2011-12, Vol.334 (6060), p.1289-1293

2011

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Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs

PLoS pathogens, 2013-01, Vol.9 (1), p.e1003106-e1003106

2013

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Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

Nature, 2009-04, Vol.458 (7238), p.636-640

2009

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Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

Nature (London), 2010-09, Vol.467 (7315), p.591-595

2010

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Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

The Journal of experimental medicine, 2012-07, Vol.209 (8), p.1469-1479

2012

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Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses

PloS one, 2011-09, Vol.6 (9), p.e24078-e24078

2011

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A method for identification of HIV gp140 binding memory B cells in human blood

Journal of immunological methods, 2009-04, Vol.343 (2), p.65-67

2009

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Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and bone marrow plasma cells

Proceedings of the National Academy of Sciences - PNAS, 2011-11, Vol.108 (44), p.18044-18048

2011

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Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (15), p.6049-6054

2013

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Enhanced HIV-1 neutralization by antibody heteroligation

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (3), p.875-880

2012

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Structural basis for germline antibody recognition of HIV-1 immunogens

eLife, 2016-03, Vol.5

2016

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A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo

PLoS pathogens, 2015-10, Vol.11 (10), p.e1005238-e1005238

2015

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Broadly Neutralizing Antibodies Developed by an HIV-Positive Elite Neutralizer Exact a Replication Fitness Cost on the Contemporaneous Virus

Journal of Virology, 2012-12, Vol.86 (23), p.12676-12685

2012

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Anti-gp41 Antibodies Cloned from HIV-Infected Patients with Broadly Neutralizing Serologic Activity

Journal of Virology, 2010-05, Vol.84 (10), p.5032-5042

2010

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A robust pipeline for rapid production of versatile nanobody repertoires

Nature methods, 2014-12, Vol.11 (12), p.1253-1260

2014

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Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

Antibodies in HIV-1 Vaccine Development and Therapy

Structural Insights on the Role of Antibodies in HIV-1 Vaccine and Therapy

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies

Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies

B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV

Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice

Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design

Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses

A method for identification of HIV gp140 binding memory B cells in human blood

Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and bone marrow plasma cells

Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody

Enhanced HIV-1 neutralization by antibody heteroligation

Structural basis for germline antibody recognition of HIV-1 immunogens

A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo

Broadly Neutralizing Antibodies Developed by an HIV-Positive Elite Neutralizer Exact a Replication Fitness Cost on the Contemporaneous Virus

Anti-gp41 Antibodies Cloned from HIV-Infected Patients with Broadly Neutralizing Serologic Activity

A robust pipeline for rapid production of versatile nanobody repertoires

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