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Potent and Highly Selective Benzimidazole Inhibitors of PI3-Kinase Delta

Journal of medicinal chemistry, 2012-09, Vol.55 (17), p.7686-7695

2012

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Accurate structure prediction of biomolecular interactions with AlphaFold 3

Nature (London), 2024-06, Vol.630 (8016), p.493-500

2024

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Discovery of Novel Allosteric Mitogen-Activated Protein Kinase Kinase (MEK) 1,2 Inhibitors Possessing Bidentate Ser212 Interactions

Journal of medicinal chemistry, 2012-05, Vol.55 (10), p.4594-4604

2012

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Structure based design of novel 6,5 heterobicyclic mitogen-activated protein kinase kinase (MEK) inhibitors leading to the discovery of imidazo[1,5-a] pyrazine G-479

Bioorganic & medicinal chemistry letters, 2014-10, Vol.24 (19), p.4714-4723

2014

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Identification of N-sulfonyl-tetrahydroquinolines as RORc inverse agonists

Bioorganic & medicinal chemistry letters, 2015-10, Vol.25 (19), p.4109-4113

2015

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Bcl-2/Bcl-xL inhibition increases the efficacy of MEK inhibition alone and in combination with PI3 kinase inhibition in lung and pancreatic tumor models

Molecular cancer therapeutics, 2013-06, Vol.12 (6), p.853-864

2013

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Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists

Bioorganic & medicinal chemistry letters, 2010-04, Vol.20 (8), p.2516-2519

2010

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Aromatic Sulfide Inhibitors of Histone Deacetylase Based on Arylsulfinyl-2,4-hexadienoic Acid Hydroxyamides

Journal of medicinal chemistry, 2006-01, Vol.49 (2), p.800-805

2006

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Bicyclic anti-VZV nucleosides: Thieno analogues retain full antiviral activity

Bioorganic & medicinal chemistry letters, 2001-09, Vol.11 (18), p.2507-2510

2001

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DNA triplex structures are stabilized by the incorporation of 3′- endo blocked pyrimidine nucleosides in the hoogsteen strand

Bioorganic & medicinal chemistry letters, 2000-10, Vol.10 (20), p.2287-2289

2000

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Binding properties of oligonucleotides containing a modified 2'-deoxyuridine with a thymine ended linker to pair with 2'-deoxyadenosine

Bioorganic & medicinal chemistry letters, 2002-03, Vol.12 (6), p.981-983

2002

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Synthesis of A Novel Sialyl Lewis X Analogue Containing A Pyrrolidine in Place of N-Acetyl Glucosamine

Journal of carbohydrate chemistry, 2000-01, Vol.19 (4-5), p.485-501

2000

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ChemInform Abstract: Synthesis of a Novel Sialyl Lewis X Analogue Containing a Pyrrolidine in Place of N-Acetyl Glucosamine

ChemInform, 2000-11, Vol.31 (46), p.no-no

2000

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ChemInform Abstract: DNA Triplex Structures Are Stabilized by the Incorporation of 3′-endo Blocked Pyrimidine Nucleosides in the Hoogsteen Strand

ChemInform, 2001-01, Vol.32 (5), p.no-no

2001

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ChemInform Abstract: Bicyclic Anti-VZV Nucleosides: Thieno Analogues Retain Full Antiviral Activity

ChemInform, 2002-02, Vol.33 (6), p.no-no

2002

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Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants

The Lancet (British edition), 2020-11, Vol.396 (10261), p.1511-1524

2020

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A workflow to process 3D+time microscopy images of developing organisms and reconstruct their cell lineage

Nature communications, 2016-02, Vol.7 (1), p.8674-8674, Article 8674

2016

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Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Nature (London), 2019, Vol.569 (7755), p.260-264

2019

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Economic impact of generic antiretrovirals in France for HIV patients' care: a simulation between 2019 and 2023

BMC health services research, 2022-04, Vol.22 (1), p.567-567, Article 567

2022

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Méthodologies de délimitation des zones humides : de l'image satellitale à l'analyse terrain (Methodology of wetlands delimitation : from sensed data to field works)

Bulletin de l'Association de géographes français, 2005, Vol.82 (2), p.246-255

2005

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Potent and Highly Selective Benzimidazole Inhibitors of PI3-Kinase Delta

Accurate structure prediction of biomolecular interactions with AlphaFold 3

Discovery of Novel Allosteric Mitogen-Activated Protein Kinase Kinase (MEK) 1,2 Inhibitors Possessing Bidentate Ser212 Interactions

Structure based design of novel 6,5 heterobicyclic mitogen-activated protein kinase kinase (MEK) inhibitors leading to the discovery of imidazo[1,5-a] pyrazine G-479

Identification of N-sulfonyl-tetrahydroquinolines as RORc inverse agonists

Bcl-2/Bcl-xL inhibition increases the efficacy of MEK inhibition alone and in combination with PI3 kinase inhibition in lung and pancreatic tumor models

Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists

Aromatic Sulfide Inhibitors of Histone Deacetylase Based on Arylsulfinyl-2,4-hexadienoic Acid Hydroxyamides

Bicyclic anti-VZV nucleosides: Thieno analogues retain full antiviral activity

DNA triplex structures are stabilized by the incorporation of 3′- endo blocked pyrimidine nucleosides in the hoogsteen strand

Binding properties of oligonucleotides containing a modified 2'-deoxyuridine with a thymine ended linker to pair with 2'-deoxyadenosine

Synthesis of A Novel Sialyl Lewis X Analogue Containing A Pyrrolidine in Place of N-Acetyl Glucosamine

ChemInform Abstract: Synthesis of a Novel Sialyl Lewis X Analogue Containing a Pyrrolidine in Place of N-Acetyl Glucosamine

ChemInform Abstract: DNA Triplex Structures Are Stabilized by the Incorporation of 3′-endo Blocked Pyrimidine Nucleosides in the Hoogsteen Strand

ChemInform Abstract: Bicyclic Anti-VZV Nucleosides: Thieno Analogues Retain Full Antiviral Activity

Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants

A workflow to process 3D+time microscopy images of developing organisms and reconstruct their cell lineage

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Economic impact of generic antiretrovirals in France for HIV patients' care: a simulation between 2019 and 2023

Méthodologies de délimitation des zones humides : de l'image satellitale à l'analyse terrain (Methodology of wetlands delimitation : from sensed data to field works)

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