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Stereocontrolled synthesis of spirocyclics

Tetrahedron, 1999-07, Vol.55 (30), p.9007-9071

Sannigrahi, Mousumi

1999

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Synthesis of Optically Pure (+)-Puraquinonic Acid and Assignment of Absolute Configuration to Natural (−)-Puraquinonic Acid. Use of Radical Cyclization for Asymmetric Generation of a Quaternary Center

Journal of organic chemistry, 2004-06, Vol.69 (12), p.4116-4125

2004

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Syntheses of dipeptides containing (1 R,5 S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2( S)-carboxylic acid ( 4), (1 R,5 S)-spiro[3-azabicyclo[3.1.0]hexane-6,1′-cyclopropane]- 2( S)-carboxylic acid ( 5) and (1 S,5 R)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2( S)-carboxylic acid ( 6)

Tetrahedron letters, 2006-09, Vol.47 (36), p.6469-6472

2006

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Direct Measurement of Enol Ether Radical Cation Reaction Kinetics

Journal of the American Chemical Society, 2001-07, Vol.123 (26), p.6445-6446

2001

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Applications of 5-Endo-trigonal Cyclization: Construction of Compounds Relevant to the Synthesis of Prostaglandins and Methyl epi-Jasmonate

Journal of organic chemistry, 1999-04, Vol.64 (8), p.2776-2788

1999

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Cyclic Sulfones as Novel P3-Caps for Hepatitis C Virus NS3/4A (HCV NS3/4A) Protease Inhibitors: Synthesis and Evaluation of Inhibitors with Improved Potency and Pharmacokinetic Profiles

Journal of medicinal chemistry, 2010-04, Vol.53 (8), p.3075-3085

2010

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Structure–Activity Relationship (SAR) Development and Discovery of Potent Indole-Based Inhibitors of the Hepatitis C Virus (HCV) NS5B Polymerase

Journal of medicinal chemistry, 2012-01, Vol.55 (2), p.754-765

2012

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I. Novel HCV NS5B polymerase inhibitors: Discovery of indole 2-carboxylic acids with C3-heterocycles

Bioorganic & medicinal chemistry letters, 2011-09, Vol.21 (18), p.5336-5341

2011

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A Facile and Efficient Synthesis of 3,3-Dimethyl Isopropylidene Proline From (+)-3-Carene

Journal of organic chemistry, 2010-02, Vol.75 (4), p.1285-1288

2010

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The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir®: A change in direction in the search for a second generation HCV NS3 protease inhibitor

Bioorganic & medicinal chemistry letters, 2010-04, Vol.20 (8), p.2617-2621

2010

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Design, Synthesis, and Evaluation of Oxygen-Containing Macrocyclic Peptidomimetics as Inhibitors of HCV NS3 Protease

Journal of medicinal chemistry, 2009-02, Vol.52 (3), p.700-708

2009

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Discovery of an irreversible HCV NS5B polymerase inhibitor

Bioorganic & medicinal chemistry letters, 2013-12, Vol.23 (24), p.6585-6587

2013

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Rapid assembly of tetrahydrodibenzofurans and tetrahydrocarbazoles from benzene and o-iodophenols and o-iodoanilines: reductive radical arylation of benzene in action

Tetrahedron, 2002-04, Vol.58 (17), p.3319-3322

2002

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II. Novel HCV NS5B polymerase inhibitors: Discovery of indole C2 acyl sulfonamides

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.713-717

2012

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Toward Second Generation Hepatitis C Virus NS3 Serine Protease Inhibitors: Discovery of Novel P4 Modified Analogues with Improved Potency and Pharmacokinetic Profile

Journal of medicinal chemistry, 2009-05, Vol.52 (9), p.2806-2817

2009

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Stereoselective Synthesis of β-Substituted β-Amino Sulfones and Sulfonamides via Addition of Sulfonyl Anions to Chiral N-Sulfinyl Imines

Organic letters, 2006-02, Vol.8 (4), p.789-792

2006

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P4 capped amides and lactams as HCV NS3 protease inhibitors with improved potency and DMPK profile

Bioorganic & medicinal chemistry letters, 2010-01, Vol.20 (2), p.567-570

2010

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Novel synthesis of sterically hindered N-substituted lactams from imides

Tetrahedron letters, 2006-07, Vol.47 (28), p.4877-4880

2006

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Synthesis of (±)-Puraquinonic Acid: An Inducer of Cell Differentiation

Journal of organic chemistry, 2001-02, Vol.66 (3), p.954-961

2001

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Carboxy mediated stereoselective reduction of ketones with sodium triacetoxyborohydride: synthesis of novel 3,4-fused tetrahydropyran and tetrahydrofuran prolines

Tetrahedron letters, 2004-08, Vol.45 (32), p.6097-6100

2004

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Cyclofunctionalization of Unsaturated Alcohols, Phenols, Acids, and Sulfonamides with 1-Benzenesulfinyl Piperidine and Trifluoromethanesulfonic Anhydride

Heterocycles, 2004, Vol.62 (1), p.827

2004

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Synthetic applications of 5-endo-trigonal cyclization, and synthetic studies related to puraquinonic acid

Sannigrahi, Mousumi

2000

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On the structure of S 4 2+ and its formation from 2S 2 + • Ab initio SCF and CASSCF studies

Canadian journal of chemistry, 1994-02, Vol.72 (2), p.298-303

1994

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Applications of 5-E ndo-trigonal Cyclization: Construction of Compounds Relevant to the Synthesis of Prostaglandins and Methyl e pi-Jasmonate

Journal of organic chemistry, 1999-04, Vol.64 (8), p.2776-2788

1999

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Discovery of Narlaprevir (SCH 900518): A Potent, Second Generation HCV NS3 Serine Protease Inhibitor

Stereocontrolled synthesis of spirocyclics

Synthesis of Optically Pure (+)-Puraquinonic Acid and Assignment of Absolute Configuration to Natural (−)-Puraquinonic Acid. Use of Radical Cyclization for Asymmetric Generation of a Quaternary Center

Syntheses of dipeptides containing (1 R,5 S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2( S)-carboxylic acid ( 4), (1 R,5 S)-spiro[3-azabicyclo[3.1.0]hexane-6,1′-cyclopropane]- 2( S)-carboxylic acid ( 5) and (1 S,5 R)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2( S)-carboxylic acid ( 6)

Direct Measurement of Enol Ether Radical Cation Reaction Kinetics

Applications of 5-Endo-trigonal Cyclization: Construction of Compounds Relevant to the Synthesis of Prostaglandins and Methyl epi-Jasmonate

Cyclic Sulfones as Novel P3-Caps for Hepatitis C Virus NS3/4A (HCV NS3/4A) Protease Inhibitors: Synthesis and Evaluation of Inhibitors with Improved Potency and Pharmacokinetic Profiles

Structure–Activity Relationship (SAR) Development and Discovery of Potent Indole-Based Inhibitors of the Hepatitis C Virus (HCV) NS5B Polymerase

I. Novel HCV NS5B polymerase inhibitors: Discovery of indole 2-carboxylic acids with C3-heterocycles

A Facile and Efficient Synthesis of 3,3-Dimethyl Isopropylidene Proline From (+)-3-Carene

The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir®: A change in direction in the search for a second generation HCV NS3 protease inhibitor

Design, Synthesis, and Evaluation of Oxygen-Containing Macrocyclic Peptidomimetics as Inhibitors of HCV NS3 Protease

Discovery of an irreversible HCV NS5B polymerase inhibitor

Rapid assembly of tetrahydrodibenzofurans and tetrahydrocarbazoles from benzene and o-iodophenols and o-iodoanilines: reductive radical arylation of benzene in action

II. Novel HCV NS5B polymerase inhibitors: Discovery of indole C2 acyl sulfonamides

Toward Second Generation Hepatitis C Virus NS3 Serine Protease Inhibitors: Discovery of Novel P4 Modified Analogues with Improved Potency and Pharmacokinetic Profile

Stereoselective Synthesis of β-Substituted β-Amino Sulfones and Sulfonamides via Addition of Sulfonyl Anions to Chiral N-Sulfinyl Imines

P4 capped amides and lactams as HCV NS3 protease inhibitors with improved potency and DMPK profile

Novel synthesis of sterically hindered N-substituted lactams from imides

Synthesis of (±)-Puraquinonic Acid: An Inducer of Cell Differentiation

Carboxy mediated stereoselective reduction of ketones with sodium triacetoxyborohydride: synthesis of novel 3,4-fused tetrahydropyran and tetrahydrofuran prolines

Cyclofunctionalization of Unsaturated Alcohols, Phenols, Acids, and Sulfonamides with 1-Benzenesulfinyl Piperidine and Trifluoromethanesulfonic Anhydride

Synthetic applications of 5-endo-trigonal cyclization, and synthetic studies related to puraquinonic acid

On the structure of S 4 2+ and its formation from 2S 2 + • Ab initio SCF and CASSCF studies

Applications of 5-E ndo-trigonal Cyclization: Construction of Compounds Relevant to the Synthesis of Prostaglandins and Methyl e pi-Jasmonate

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