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Discovery of a chemical probe for PRDM9

Nature communications, 2019-12, Vol.10 (1), p.5759-11, Article 5759

2019

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Angiogenesis in skeletal muscle precede improvements in peak oxygen uptake in peripheral artery disease patients

Arteriosclerosis, thrombosis, and vascular biology, 2011-11, Vol.31 (11), p.2742-2748

2011

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Molecular Imaging of Endothelial Vascular Cell Adhesion Molecule-1 Expression and Inflammatory Cell Recruitment During Vasculogenesis and Ischemia-Mediated Arteriogenesis

Circulation (New York, N.Y.), 2008-06, Vol.117 (22), p.2902-2911

2008

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Maximizing Diversity from a Kinase Screen: Identification of Novel and Selective pan-Trk Inhibitors for Chronic Pain

Journal of medicinal chemistry, 2014-07, Vol.57 (13), p.5800-5816

2014

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NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells

The FASEB journal, 2010-01, Vol.24 (1), p.39-48

2010

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Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice

Arteriosclerosis, thrombosis, and vascular biology, 2008-11, Vol.28 (11), p.2003-2008

2008

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Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis

The Journal of cell biology, 2007-02, Vol.176 (5), p.719-727

2007

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Discovery and optimization of 2-pyridinone aminal integrase strand transfer inhibitors for the treatment of HIV

Bioorganic & medicinal chemistry letters, 2017-05, Vol.27 (9), p.2038-2046

2017

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Improved Survival and Reduced Vascular Permeability by Eliminating or Blocking 12/15-Lipoxygenase in Mouse Models of Acute Lung Injury (ALI)

The Journal of immunology (1950), 2009-10, Vol.183 (7), p.4715-4722

2009

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Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT)

ACS medicinal chemistry letters, 2015-03, Vol.6 (3), p.318-323

2015

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Discovery of a 3‑(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity

Journal of medicinal chemistry, 2017-04, Vol.60 (7), p.2983-2992

2017

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Single injection of P-selectin or P-selectin glycoprotein ligand-1 monoclonal antibody blocks neointima formation after arterial injury in apolipoprotein E-deficient mice

Circulation (New York, N.Y.), 2003-05, Vol.107 (17), p.2244-2249

2003

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Molecular imaging of inflammation in atherosclerosis with targeted ultrasound detection of vascular cell adhesion molecule-1

Circulation (New York, N.Y.), 2007-07, Vol.116 (3), p.276-284

2007

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Optimal π-Stacking Interaction Energies in Parallel-Displaced Aryl/Aryl Dimers are Predicted by the Dimer Heavy Atom Count

The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 2010-09, Vol.114 (34), p.9205-9211

Sanders, John M

2010

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Adeno-associated virus serotype 9-mediated overexpression of extracellular superoxide dismutase improves recovery from surgical hind-limb ischemia in BALB/c mice

Journal of vascular surgery, 2011-09, Vol.54 (3), p.810-818

2011

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3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3129-3133

2010

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Crystallographic Structures of Two Bisphosphonate:1-Deoxyxylulose-5-Phosphate Reductoisomerase Complexes

Journal of the American Chemical Society, 2004-09, Vol.126 (35), p.10824-10825

2004

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Augmenting Hit Identification by Virtual Screening Techniques in Small Molecule Drug Discovery

Journal of chemical information and modeling, 2020-09, Vol.60 (9), p.4144-4152

2020

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Rosiglitazone reduces the accelerated neointima formation after arterial injury in a mouse injury model of type 2 diabetes

Circulation (New York, N.Y.), 2003-10, Vol.108 (16), p.1994-1999

2003

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Arterial Macrophages and Regenerating Endothelial Cells Express P-Selectin in Atherosclerosis-Prone Apolipoprotein E-Deficient Mice

The American journal of pathology, 2005-12, Vol.167 (6), p.1511-1518

2005

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Integrin Agonists as Adjuvants in Chemotherapy for Melanoma

Clinical cancer research, 2008-10, Vol.14 (19), p.6193-6197

2008

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Structural characterization of nonactive site, TrkA-selective kinase inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (3), p.E297-E306

2017

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Inhibition of Geranylgeranyl Diphosphate Synthase by Bisphosphonates and Diphosphates: A Potential Route to New Bone Antiresorption and Antiparasitic Agents

Journal of medicinal chemistry, 2002-05, Vol.45 (11), p.2185-2196

2002

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CXCR6 promotes atherosclerosis by supporting T-cell homing, interferon-γ production, and macrophage accumulation in the aortic wall

Circulation (New York, N.Y.), 2007-10, Vol.116 (16), p.1801-1811

2007

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The Subendothelial Extracellular Matrix Modulates JNK Activation by Flow

Circulation research, 2009-04, Vol.104 (8), p.995-1003

2009

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Discovery of a chemical probe for PRDM9

Angiogenesis in skeletal muscle precede improvements in peak oxygen uptake in peripheral artery disease patients

Molecular Imaging of Endothelial Vascular Cell Adhesion Molecule-1 Expression and Inflammatory Cell Recruitment During Vasculogenesis and Ischemia-Mediated Arteriogenesis

Maximizing Diversity from a Kinase Screen: Identification of Novel and Selective pan-Trk Inhibitors for Chronic Pain

NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells

Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice

Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis

Discovery and optimization of 2-pyridinone aminal integrase strand transfer inhibitors for the treatment of HIV

Improved Survival and Reduced Vascular Permeability by Eliminating or Blocking 12/15-Lipoxygenase in Mouse Models of Acute Lung Injury (ALI)

Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT)

Discovery of a 3‑(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity

Single injection of P-selectin or P-selectin glycoprotein ligand-1 monoclonal antibody blocks neointima formation after arterial injury in apolipoprotein E-deficient mice

Molecular imaging of inflammation in atherosclerosis with targeted ultrasound detection of vascular cell adhesion molecule-1

Optimal π-Stacking Interaction Energies in Parallel-Displaced Aryl/Aryl Dimers are Predicted by the Dimer Heavy Atom Count

Adeno-associated virus serotype 9-mediated overexpression of extracellular superoxide dismutase improves recovery from surgical hind-limb ischemia in BALB/c mice

3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts

Crystallographic Structures of Two Bisphosphonate:1-Deoxyxylulose-5-Phosphate Reductoisomerase Complexes

Augmenting Hit Identification by Virtual Screening Techniques in Small Molecule Drug Discovery

Rosiglitazone reduces the accelerated neointima formation after arterial injury in a mouse injury model of type 2 diabetes

Arterial Macrophages and Regenerating Endothelial Cells Express P-Selectin in Atherosclerosis-Prone Apolipoprotein E-Deficient Mice

Integrin Agonists as Adjuvants in Chemotherapy for Melanoma

Structural characterization of nonactive site, TrkA-selective kinase inhibitors

Inhibition of Geranylgeranyl Diphosphate Synthase by Bisphosphonates and Diphosphates: A Potential Route to New Bone Antiresorption and Antiparasitic Agents

CXCR6 promotes atherosclerosis by supporting T-cell homing, interferon-γ production, and macrophage accumulation in the aortic wall

The Subendothelial Extracellular Matrix Modulates JNK Activation by Flow

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