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Development of siRNA Delivery System by Lipid Nanoparticles Modified with Functional Materials for Cancer Treatment

Biological and Pharmaceutical Bulletin, 2022/08/01, Vol.45(8), pp.972-977

Sakurai, Yu

2022

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A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo

Journal of controlled release, 2012-11, Vol.163 (3), p.267-276

2012

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Targeting Tumor Endothelial Cells with Nanoparticles

International journal of molecular sciences, 2019-11, Vol.20 (23), p.5819

2019

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Proteomics Analysis of Lymphatic Metastasis-Related Proteins Using Highly Metastatic Human Melanoma Cells Originated by Sequential in Vivo Implantation

Biological and Pharmaceutical Bulletin, 2021/10/01, Vol.44(10), pp.1551-1556

2021

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Modality of tumor endothelial VEGFR2 silencing-mediated improvement in intratumoral distribution of lipid nanoparticles

Journal of controlled release, 2017-04, Vol.251, p.1-10

2017

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The stress-responsive cytotoxic effect of diesel exhaust particles on lymphatic endothelial cells

Scientific reports, 2024-05, Vol.14 (1), p.10503-10503, Article 10503

2024

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Self‐Degradable Lipid‐Like Materials Based on “Hydrolysis accelerated by the intra‐Particle Enrichment of Reactant (HyPER)” for Messenger RNA Delivery

Advanced functional materials, 2020-08, Vol.30 (34), p.n/a

2020

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Lymphatic Endothelial Cells Produce Chemokines in Response to the Lipid Nanoparticles Used in RNA Vaccines

Biological and Pharmaceutical Bulletin, 2024/03/26, Vol.47(3), pp.698-707

2024

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Novel antiangiogenic therapy targeting biglycan using tumor endothelial cell‐specific liposomal siRNA delivery system

Cancer science, 2022-05, Vol.113 (5), p.1855-1867

2022

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Remodeling of the Extracellular Matrix by Endothelial Cell-Targeting siRNA Improves the EPR-Based Delivery of 100 nm Particles

Molecular therapy, 2016-12, Vol.24 (12), p.2090-2099

2016

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Targeted delivery of lipid nanoparticle to lymphatic endothelial cells via anti-podoplanin antibody

Journal of controlled release, 2022-09, Vol.349, p.379-387

2022

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RNAi-mediated gene knockdown and anti-angiogenic therapy of RCCs using a cyclic RGD-modified liposomal-siRNA system

Journal of controlled release, 2014-01, Vol.173, p.110-118

2014

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Modifying Cationic Liposomes with Cholesteryl-PEG Prevents Their Aggregation in Human Urine and Enhances Cellular Uptake by Bladder Cancer Cells

Biological and Pharmaceutical Bulletin, 2017/02/01, Vol.40(2), pp.234-237

2017

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Advances in an active and passive targeting to tumor and adipose tissues

Expert opinion on drug delivery, 2015-01, Vol.12 (1), p.41-52

2015

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Failure of active targeting by a cholesterol-anchored ligand and improvement by altering the lipid composition to prevent ligand desorption

International journal of pharmaceutics, 2018-01, Vol.536 (1), p.42-49

2018

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siRNA delivery to lymphatic endothelial cells via ApoE-mediated uptake by lipid nanoparticles

Journal of controlled release, 2023-01, Vol.353, p.125-133

2023

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Improvement of Doxorubicin Efficacy Using Liposomal Anti-Polo-like Kinase 1 siRNA in Human Renal Cell Carcinomas

Molecular pharmaceutics, 2014-08, Vol.11 (8), p.2713-2719

2014

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Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine‐Loaded Lipid Nanoparticles

Advanced healthcare materials, 2023-04, Vol.12 (9), p.e2202528-n/a

2023

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Endosomal escape and the knockdown efficiency of liposomal-siRNA by the fusogenic peptide shGALA

Biomaterials, 2011-08, Vol.32 (24), p.5733-5742

2011

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Mitochondrial Delivery of Doxorubicin Using MITO-Porter Kills Drug-Resistant Renal Cancer Cells via Mitochondrial Toxicity

Journal of pharmaceutical sciences, 2017-09, Vol.106 (9), p.2428-2437

2017

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Silencing of VEGFR2 by RGD-Modified Lipid Nanoparticles Enhanced the Efficacy of Anti-PD-1 Antibody by Accelerating Vascular Normalization and Infiltration of T Cells in Tumors

Cancers, 2020-12, Vol.12 (12), p.3630

2020

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Liver-Specific Silencing of Lipin1 Reduces Fat Mass as Well as Hepatic Triglyceride Biosynthesis in Mice

Biological and Pharmaceutical Bulletin, 2016/10/01, Vol.39(10), pp.1653-1661

2016

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Optimization of Sentinel Lymph Node Imaging Methodology Using Anionic Liposome and Hyaluronidase

Pharmaceutics, 2021-09, Vol.13 (9), p.1462

2021

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Efficient Packaging of Plasmid DNA Using a pH Sensitive Cationic Lipid for Delivery to Hepatocytes

Biological and Pharmaceutical Bulletin, 2015/08/01, Vol.38(8), pp.1185-1191

2015

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Innovative Technologies in Nanomedicines: From Passive Targeting to Active Targeting/From Controlled Pharmacokinetics to Controlled Intracellular Pharmacokinetics

Macromolecular bioscience, 2017-01, Vol.17 (1), p.np-n/a

2017

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Development of siRNA Delivery System by Lipid Nanoparticles Modified with Functional Materials for Cancer Treatment

A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo

Targeting Tumor Endothelial Cells with Nanoparticles

Proteomics Analysis of Lymphatic Metastasis-Related Proteins Using Highly Metastatic Human Melanoma Cells Originated by Sequential in Vivo Implantation

Modality of tumor endothelial VEGFR2 silencing-mediated improvement in intratumoral distribution of lipid nanoparticles

The stress-responsive cytotoxic effect of diesel exhaust particles on lymphatic endothelial cells

Self‐Degradable Lipid‐Like Materials Based on “Hydrolysis accelerated by the intra‐Particle Enrichment of Reactant (HyPER)” for Messenger RNA Delivery

Lymphatic Endothelial Cells Produce Chemokines in Response to the Lipid Nanoparticles Used in RNA Vaccines

Novel antiangiogenic therapy targeting biglycan using tumor endothelial cell‐specific liposomal siRNA delivery system

Remodeling of the Extracellular Matrix by Endothelial Cell-Targeting siRNA Improves the EPR-Based Delivery of 100 nm Particles

Targeted delivery of lipid nanoparticle to lymphatic endothelial cells via anti-podoplanin antibody

RNAi-mediated gene knockdown and anti-angiogenic therapy of RCCs using a cyclic RGD-modified liposomal-siRNA system

Modifying Cationic Liposomes with Cholesteryl-PEG Prevents Their Aggregation in Human Urine and Enhances Cellular Uptake by Bladder Cancer Cells

Advances in an active and passive targeting to tumor and adipose tissues

Failure of active targeting by a cholesterol-anchored ligand and improvement by altering the lipid composition to prevent ligand desorption

siRNA delivery to lymphatic endothelial cells via ApoE-mediated uptake by lipid nanoparticles

Improvement of Doxorubicin Efficacy Using Liposomal Anti-Polo-like Kinase 1 siRNA in Human Renal Cell Carcinomas

Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine‐Loaded Lipid Nanoparticles

Endosomal escape and the knockdown efficiency of liposomal-siRNA by the fusogenic peptide shGALA

Mitochondrial Delivery of Doxorubicin Using MITO-Porter Kills Drug-Resistant Renal Cancer Cells via Mitochondrial Toxicity

Silencing of VEGFR2 by RGD-Modified Lipid Nanoparticles Enhanced the Efficacy of Anti-PD-1 Antibody by Accelerating Vascular Normalization and Infiltration of T Cells in Tumors

Liver-Specific Silencing of Lipin1 Reduces Fat Mass as Well as Hepatic Triglyceride Biosynthesis in Mice

Optimization of Sentinel Lymph Node Imaging Methodology Using Anionic Liposome and Hyaluronidase

Efficient Packaging of Plasmid DNA Using a pH Sensitive Cationic Lipid for Delivery to Hepatocytes

Innovative Technologies in Nanomedicines: From Passive Targeting to Active Targeting/From Controlled Pharmacokinetics to Controlled Intracellular Pharmacokinetics

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