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The role of MDA5 in the development of autoimmune disease

Journal of leukocyte biology, 2018-02, Vol.103 (2), p.185-192

Sadler, Anthony J.

2018

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Inhibition of UBA6 by inosine augments tumour immunogenicity and responses

Nature communications, 2022-09, Vol.13 (1), p.5413-5413, Article 5413

2022

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ATF3 Suppresses Metastasis of Bladder Cancer by Regulating Gelsolin-Mediated Remodeling of the Actin Cytoskeleton

Cancer research (Chicago, Ill.), 2013-06, Vol.73 (12), p.3625-3637

2013

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Regulation of Actin Dynamics by Protein Kinase R Control of Gelsolin Enforces Basal Innate Immune Defense

Immunity (Cambridge, Mass.), 2012-05, Vol.36 (5), p.795-806

2012

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The kinase activity of PKR represses inflammasome activity

Cell research, 2016-03, Vol.26 (3), p.367-379

2016

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A Viral NOD to Encephalitis

Journal of virology, 2022-07, Vol.96 (13), p.e0045422-e0045422

2022

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The protein kinase R modifies gut physiology to limit colitis

Frontiers in immunology, 2023-02, Vol.14, p.1106737-1106737

2023

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BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (5), p.1535-1540

2015

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An antiviral response directed by PKR phosphorylation of the RNA helicase A

PLoS pathogens, 2009-02, Vol.5 (2), p.e1000311-e1000311

2009

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Promyelocytic Leukemia Zinc Finger Protein Regulates Interferon-Mediated Innate Immunity

Immunity (Cambridge, Mass.), 2009-06, Vol.30 (6), p.802-816

2009

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Fine-tuning of the innate immune response by microRNAs

Immunology and cell biology, 2007-08, Vol.85 (6), p.458-462

2007

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Dynamiting Viruses with MxA

Immunity (Cambridge, Mass.), 2011-10, Vol.35 (4), p.491-493

2011

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Interferon-inducible antiviral effectors

Nature reviews. Immunology, 2008-07, Vol.8 (7), p.559-568

2008

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The immune response to RNA suppresses nucleic acid synthesis by limiting ribose 5-phosphate

The EMBO journal, 2024-07, Vol.43 (13), p.2636-2660

2024

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Protein Kinase R-dependent Regulation of Interleukin-10 in Response to Double-stranded RNA

The Journal of biological chemistry, 2008-09, Vol.283 (37), p.25132-25139

2008

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The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation

The EMBO journal, 2017-09, Vol.36 (18), p.2742-2757

2017

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The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF

Nature communications, 2015-04, Vol.6 (1), p.6795-6795, Article 6795

2015

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Molecular dynamics reveal a novel kinase-substrate interface that regulates protein translation

Journal of molecular cell biology, 2014-12, Vol.6 (6), p.473

2014

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The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53

Oncogene, 2018-04, Vol.37 (14), p.1939-1948

2018

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Auto-phosphorylation Represses Protein Kinase R Activity

Scientific reports, 2017-03, Vol.7 (1), p.44340-44340, Article 44340

2017

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protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development

The FEBS journal, 2015-12, Vol.282 (24), p.4766-4781

2015

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Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly

Nucleic acids research, 2013-03, Vol.41 (5), p.3436

2013

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Orchestration of the activation of protein kinase R by the RNA-binding motif

Journal of interferon & cytokine research, 2010-04, Vol.30 (4), p.195

Sadler, Anthony J

2010

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Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling

EMBO reports, 2013-09, Vol.14 (9), p.837-844

2013

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The role of MDA5 in the development of autoimmune disease

Inhibition of UBA6 by inosine augments tumour immunogenicity and responses

ATF3 Suppresses Metastasis of Bladder Cancer by Regulating Gelsolin-Mediated Remodeling of the Actin Cytoskeleton

Regulation of Actin Dynamics by Protein Kinase R Control of Gelsolin Enforces Basal Innate Immune Defense

The kinase activity of PKR represses inflammasome activity

A Viral NOD to Encephalitis

The protein kinase R modifies gut physiology to limit colitis

BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs

An antiviral response directed by PKR phosphorylation of the RNA helicase A

Promyelocytic Leukemia Zinc Finger Protein Regulates Interferon-Mediated Innate Immunity

Fine-tuning of the innate immune response by microRNAs

Dynamiting Viruses with MxA

Interferon-inducible antiviral effectors

The immune response to RNA suppresses nucleic acid synthesis by limiting ribose 5-phosphate

Protein Kinase R-dependent Regulation of Interleukin-10 in Response to Double-stranded RNA

The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation

The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF

Molecular dynamics reveal a novel kinase-substrate interface that regulates protein translation

The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53

Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24

Auto-phosphorylation Represses Protein Kinase R Activity

protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development

Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly

Orchestration of the activation of protein kinase R by the RNA-binding motif

Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling

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