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Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia

Molecular cancer, 2023-12, Vol.22 (1), p.196-196, Article 196

2023

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Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature

Human molecular genetics, 2020-05, Vol.29 (7), p.1132-1143

2020

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Role of Proteasomes in Inflammation

Journal of clinical medicine, 2021-04, Vol.10 (8), p.1783

2021

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The Ubiquitin-Proteasome System in Immune Cells

Biomolecules (Basel, Switzerland), 2021-01, Vol.11 (1), p.60

2021

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Proteasome β5i Subunit Deficiency Affects Opsonin Synthesis and Aggravates Pneumococcal Pneumonia

PloS one, 2016-04, Vol.11 (4), p.e0153847-e0153847

2016

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Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells

The Journal of experimental medicine, 2010-06, Vol.207 (6), p.1273-1281

2010

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Contribution of the Unfolded Protein Response (UPR) to the Pathogenesis of Proteasome-Associated Autoinflammatory Syndromes (PRAAS)

Frontiers in immunology, 2019-11, Vol.10, p.2756-2756

2019

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The Proteasome Activator PA200/PSME4: An Emerging New Player in Health and Disease

Biomolecules (Basel, Switzerland), 2022-08, Vol.12 (8), p.1150

2022

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Molecular Insight Into the IRE1α-Mediated Type I Interferon Response Induced by Proteasome Impairment in Myeloid Cells of the Brain

Frontiers in immunology, 2019-12, Vol.10, p.2900-2900

2019

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Emerging roles of immunoproteasomes beyond MHC class I antigen processing

Cellular and molecular life sciences : CMLS, 2012-08, Vol.69 (15), p.2543-2558

2012

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Neurodevelopmental Disorders (NDD) Caused by Genomic Alterations of the Ubiquitin-Proteasome System (UPS): the Possible Contribution of Immune Dysregulation to Disease Pathogenesis

Frontiers in molecular neuroscience, 2021-09, Vol.14, p.733012-733012

2021

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Immunoproteasomes Preserve Protein Homeostasis upon Interferon-Induced Oxidative Stress

Cell, 2010-08, Vol.142 (4), p.613-624

2010

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Proteostasis Perturbations and Their Roles in Causing Sterile Inflammation and Autoinflammatory Diseases

Cells (Basel, Switzerland), 2022-04, Vol.11 (9), p.1422

2022

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Regulation der Proteostase – ein Fokus auf das Ubiquitin-Proteasomen-System

Biospektrum, 2017-06, Vol.23 (4), p.379-383

2017

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Regulation der Proteostase – ein Fokus auf das Ubiquitin-Proteasomen-System: Proteostase und Immunantwort

Biospektrum, 2017-06, Vol.23 (4), p.379-383

2017

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GestaltMatcher facilitates rare disease matching using facial phenotype descriptors

Nature genetics, 2022-03, Vol.54 (3), p.349-357

2022

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Immunogenic cell death triggered by impaired deubiquitination in multiple myeloma relies on dysregulated type I interferon signaling

Frontiers in immunology, 2023-03, Vol.14, p.982720-982720

2023

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Immunoproteasomes control activation of innate immune signaling and microglial function

Frontiers in immunology, 2022-10, Vol.13, p.982786-982786

2022

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Major Histocompatibility Complex (MHC) Class I Processing of the NY-ESO-1 Antigen Is Regulated by Rpn10 and Rpn13 Proteins and Immunoproteasomes following Non-lysine Ubiquitination

The Journal of biological chemistry, 2016-04, Vol.291 (16), p.8805-8815

2016

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Cross-presentation of synthetic long peptides by human dendritic cells: a process dependent on ERAD component p97/VCP but Not sec61 and/or Derlin-1

PloS one, 2014-02, Vol.9 (2), p.e89897-e89897

2014

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Gain-of-function variants in the KDF1 gene cause hidradenitis suppurativa associated with ectodermal dysplasia by stabilizing IκB kinase α

British journal of dermatology (1951), 2023-07, Vol.189 (1), p.131-132

2023

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HSCT corrects primary immunodeficiency and immune dysregulation in patients with POMP-related autoinflammatory disease

Blood, 2021-11, Vol.138 (19), p.1896-1901

2021

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Proteasome subunit PSMC3 variants cause neurosensory syndrome combining deafness and cataract due to proteotoxic stress

Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia

Identification of eight novel proteasome variants in five unrelated cases of proteasome-associated autoinflammatory syndromes (PRAAS)

Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature

Role of Proteasomes in Inflammation

The Ubiquitin-Proteasome System in Immune Cells

Proteasome β5i Subunit Deficiency Affects Opsonin Synthesis and Aggravates Pneumococcal Pneumonia

Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells

Contribution of the Unfolded Protein Response (UPR) to the Pathogenesis of Proteasome-Associated Autoinflammatory Syndromes (PRAAS)

The Proteasome Activator PA200/PSME4: An Emerging New Player in Health and Disease

Molecular Insight Into the IRE1α-Mediated Type I Interferon Response Induced by Proteasome Impairment in Myeloid Cells of the Brain

Emerging roles of immunoproteasomes beyond MHC class I antigen processing

Neurodevelopmental Disorders (NDD) Caused by Genomic Alterations of the Ubiquitin-Proteasome System (UPS): the Possible Contribution of Immune Dysregulation to Disease Pathogenesis

Immunoproteasomes Preserve Protein Homeostasis upon Interferon-Induced Oxidative Stress

Proteostasis Perturbations and Their Roles in Causing Sterile Inflammation and Autoinflammatory Diseases

P196: GestaltMatcher Database: A FAIR database for medical imaging data of rare diseases

Regulation der Proteostase – ein Fokus auf das Ubiquitin-Proteasomen-System

Regulation der Proteostase – ein Fokus auf das Ubiquitin-Proteasomen-System: Proteostase und Immunantwort

GestaltMatcher facilitates rare disease matching using facial phenotype descriptors

Immunogenic cell death triggered by impaired deubiquitination in multiple myeloma relies on dysregulated type I interferon signaling

Immunoproteasomes control activation of innate immune signaling and microglial function

Major Histocompatibility Complex (MHC) Class I Processing of the NY-ESO-1 Antigen Is Regulated by Rpn10 and Rpn13 Proteins and Immunoproteasomes following Non-lysine Ubiquitination

Cross-presentation of synthetic long peptides by human dendritic cells: a process dependent on ERAD component p97/VCP but Not sec61 and/or Derlin-1

Gain-of-function variants in the KDF1 gene cause hidradenitis suppurativa associated with ectodermal dysplasia by stabilizing IκB kinase α

HSCT corrects primary immunodeficiency and immune dysregulation in patients with POMP-related autoinflammatory disease

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