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Functional characterization of the semisynthetic bile acid derivative INT-767, a dual farnesoid X receptor and TGR5 agonist

Molecular pharmacology, 2010-10, Vol.78 (4), p.617-630

2010

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Nongenomic Actions of Bile Acids. Synthesis and Preliminary Characterization of 23- and 6,23-Alkyl-Substituted Bile Acid Derivatives as Selective Modulators for the G-Protein Coupled Receptor TGR5

Journal of medicinal chemistry, 2007-09, Vol.50 (18), p.4265-4268

2007

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Protective effects of 6-ethyl chenodeoxycholic acid, a farnesoid X receptor ligand, in estrogen-induced cholestasis

The Journal of pharmacology and experimental therapeutics, 2005-05, Vol.313 (2), p.604-612

2005

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Bile Acid Derivatives as Ligands of the Farnesoid X Receptor. Synthesis, Evaluation, and Structure−Activity Relationship of a Series of Body and Side Chain Modified Analogues of Chenodeoxycholic Acid

Journal of medicinal chemistry, 2004-08, Vol.47 (18), p.4559-4569

2004

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Novel stereoselective synthesis and chromatographic evaluation of E-guggulsterone

Steroids, 2012-02, Vol.77 (3), p.250-254

2012

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Back Door Modulation of the Farnesoid X Receptor: Design, Synthesis, and Biological Evaluation of a Series of Side Chain Modified Chenodeoxycholic Acid Derivatives

Journal of medicinal chemistry, 2006-07, Vol.49 (14), p.4208-4215

2006

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Modulation of the Kynurenine Pathway in Search for New Neuroprotective Agents.Synthesis and Preliminary Evaluation of (m-Nitrobenzoyl)alanine, a Potent Inhibitor of Kynurenine-3-hydroxylase

Journal of medicinal chemistry, 1994-03, Vol.37 (5), p.647-655

1994

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The Reaction of α-Diazo-β-hydroxy Esters with Boron Trifluoride Etherate: Generation and Rearrangement of Destabilized Vinyl Cations. A Detailed Experimental and Theoretical Study

Journal of the American Chemical Society, 1996-01, Vol.118 (1), p.1-12

1996

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Functional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 AgonistS

Molecular pharmacology, 2010-10, Vol.78 (4), p.617-630

2010

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3 alpha -6 alpha -Dihydroxy-7 alpha -fluoro-5 beta -cholanoate (UPF-680), physicochemical and physiological properties of a new fluorinated bile acid that prevents 17 alpha -ethynyl-estradiol-induced cholestasis in rats

Toxicology and applied pharmacology, 2006-07, Vol.214 (2), p.199-208

2006

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3α-6α-Dihydroxy-7α-fluoro-5β-cholanoate (UPF-680), physicochemical and physiological properties of a new fluorinated bile acid that prevents 17α-ethynyl-estradiol-induced cholestasis in rats

Toxicology and applied pharmacology, 2006-07, Vol.214 (2), p.199-208

2006

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3alpha-6alpha-Dihydroxy-7alpha-fluoro-5beta-cholanoate (UPF-680), physicochemical and physiological properties of a new fluorinated bile acid that prevents 17alpha-ethynyl-estradiol-induced cholestasis in rats

Toxicology and applied pharmacology, 2006-07, Vol.214 (2), p.199

2006

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The reaction of α-diazo-β-hydroxy esters with boron trifluoride

Journal of the Chemical Society. Chemical communications, 1993 (24), p.1798-1800

1993

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Metabolism, pharmacokinetics, and activity of a new 6-fluoro analogue of ursodeoxycholic acid in rats and hamsters

Gastroenterology (New York, N.Y. 1943), 1995-04, Vol.108 (4), p.1204-1214

1995

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Synthesis of 6β-methoxy-6α-hydroxymethylpenems

Tetrahedron, 1995-09, Vol.51 (39), p.10723-10730

1995

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The roles of signaling pathways in bone repair and regeneration

Journal of cellular physiology, 2018-04, Vol.233 (4), p.2937-2948

2018

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Melatonin in regulation of inflammatory pathways in rheumatoid arthritis and osteoarthritis: involvement of circadian clock genes

British journal of pharmacology, 2018-08, Vol.175 (16), p.3230-3238

2018

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Melatonin: A pleiotropic molecule that modulates DNA damage response and repair pathways

Journal of pineal research, 2017-08, Vol.63 (1), p.n/a

2017

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Double domain polyethylenimine-based nanoparticles for integrin receptor mediated delivery of plasmid DNA

Scientific reports, 2018-05, Vol.8 (1), p.6842-12, Article 6842

2018

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The role of melatonin in bone regeneration: A review of involved signaling pathways

Biochimie, 2022-11, Vol.202, p.56-70

2022

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Self-Assembled Nanoparticle-Forming Derivatives of Dextrin-Conjugated Polyethylenimine Containing Urethane Bonds for Enhanced Delivery of Interleukin-12 Plasmid

Current nanoscience, 2024-08, Vol.20

2024

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Surface decoration of low molecular weight polyethylenimine (LMW PEI) by phthalated dextrin for improved delivery of interleukin‐12 plasmid

Biotechnology progress, 2024-05, Vol.40 (3), p.e3443-n/a

2024

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Modulation of telomerase expression and function by miRNAs: Anti-cancer potential

Life sciences (1973), 2020-10, Vol.259, p.118387-118387, Article 118387

2020

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Tetraiodothyroacetic acid-conjugated polyethylenimine for integrin receptor mediated delivery of the plasmid encoding IL-12 gene

Colloids and surfaces, B, Biointerfaces, 2017-02, Vol.150, p.426-436

2017

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Functional characterization of the semisynthetic bile acid derivative INT-767, a dual farnesoid X receptor and TGR5 agonist

Nongenomic Actions of Bile Acids. Synthesis and Preliminary Characterization of 23- and 6,23-Alkyl-Substituted Bile Acid Derivatives as Selective Modulators for the G-Protein Coupled Receptor TGR5

Protective effects of 6-ethyl chenodeoxycholic acid, a farnesoid X receptor ligand, in estrogen-induced cholestasis

Bile Acid Derivatives as Ligands of the Farnesoid X Receptor. Synthesis, Evaluation, and Structure−Activity Relationship of a Series of Body and Side Chain Modified Analogues of Chenodeoxycholic Acid

Novel stereoselective synthesis and chromatographic evaluation of E-guggulsterone

Back Door Modulation of the Farnesoid X Receptor: Design, Synthesis, and Biological Evaluation of a Series of Side Chain Modified Chenodeoxycholic Acid Derivatives

Modulation of the Kynurenine Pathway in Search for New Neuroprotective Agents.Synthesis and Preliminary Evaluation of (m-Nitrobenzoyl)alanine, a Potent Inhibitor of Kynurenine-3-hydroxylase

The Reaction of α-Diazo-β-hydroxy Esters with Boron Trifluoride Etherate: Generation and Rearrangement of Destabilized Vinyl Cations. A Detailed Experimental and Theoretical Study

Functional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 AgonistS

3 alpha -6 alpha -Dihydroxy-7 alpha -fluoro-5 beta -cholanoate (UPF-680), physicochemical and physiological properties of a new fluorinated bile acid that prevents 17 alpha -ethynyl-estradiol-induced cholestasis in rats

3α-6α-Dihydroxy-7α-fluoro-5β-cholanoate (UPF-680), physicochemical and physiological properties of a new fluorinated bile acid that prevents 17α-ethynyl-estradiol-induced cholestasis in rats

3{alpha}-6{alpha}-Dihydroxy-7{alpha}-fluoro-5{beta}-cholanoate (UPF-680), physicochemical and physiological properties of a new fluorinated bile acid that prevents 17{alpha}-ethynyl-estradiol-induced cholestasis in rats

3alpha-6alpha-Dihydroxy-7alpha-fluoro-5beta-cholanoate (UPF-680), physicochemical and physiological properties of a new fluorinated bile acid that prevents 17alpha-ethynyl-estradiol-induced cholestasis in rats

The reaction of α-diazo-β-hydroxy esters with boron trifluoride

Metabolism, pharmacokinetics, and activity of a new 6-fluoro analogue of ursodeoxycholic acid in rats and hamsters

Synthesis of 6β-methoxy-6α-hydroxymethylpenems

The roles of signaling pathways in bone repair and regeneration

Melatonin in regulation of inflammatory pathways in rheumatoid arthritis and osteoarthritis: involvement of circadian clock genes

Melatonin: A pleiotropic molecule that modulates DNA damage response and repair pathways

Double domain polyethylenimine-based nanoparticles for integrin receptor mediated delivery of plasmid DNA

The role of melatonin in bone regeneration: A review of involved signaling pathways

Self-Assembled Nanoparticle-Forming Derivatives of Dextrin-Conjugated Polyethylenimine Containing Urethane Bonds for Enhanced Delivery of Interleukin-12 Plasmid

Surface decoration of low molecular weight polyethylenimine (LMW PEI) by phthalated dextrin for improved delivery of interleukin‐12 plasmid

Modulation of telomerase expression and function by miRNAs: Anti-cancer potential

Tetraiodothyroacetic acid-conjugated polyethylenimine for integrin receptor mediated delivery of the plasmid encoding IL-12 gene

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