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From R-Loops to G-Quadruplexes: Emerging New Threats for the Replication Fork

International journal of molecular sciences, 2020-02, Vol.21 (4), p.1506

2020

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Elongating RNA polymerase II and RNA:DNA hybrids hinder fork progression and gene expression at sites of head-on replication-transcription collisions

Nucleic acids research, 2021-12, Vol.49 (22), p.12769

2021

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4-PBA ameliorates cellular homeostasis in fibroblasts from osteogenesis imperfecta patients by enhancing autophagy and stimulating protein secretion

Biochimica et biophysica acta. Molecular basis of disease, 2018-05, Vol.1864 (5), p.1642-1652

2018

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Sex specific regulation of TSPY-Like 2 in the DNA damage response of cancer cells

Cell death & disease, 2023-03, Vol.14 (3), p.197-197, Article 197

2023

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Homozygous substitution of threonine 191 by proline in polymerase η causes Xeroderma pigmentosum variant

Scientific reports, 2024-01, Vol.14 (1), p.1117-1117, Article 1117

2024

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Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate

Disease models & mechanisms, 2019-06, Vol.12 (6)

2019

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The Regulation of DNA Damage Tolerance by Ubiquitin and Ubiquitin-Like Modifiers

Frontiers in genetics, 2016-06, Vol.7, p.105-105

2016

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Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (42), p.16125-16130

2008

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Replication of Structured DNA and its implication in epigenetic stability

Frontiers in genetics, 2015-06, Vol.6, p.209-209

2015

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A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres

International journal of molecular sciences, 2021-03, Vol.22 (5), p.2365

2021

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Effect of proliferating cell nuclear antigen ubiquitination and chromatin structure on the dynamic properties of the Y-family DNA polymerases

Molecular biology of the cell, 2008-12, Vol.19 (12), p.5193-5202

2008

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Yeast Rev1 is cell cycle regulated, phosphorylated in response to DNA damage and its binding to chromosomes is dependent upon MEC1

DNA repair, 2007-01, Vol.6 (1), p.121-127

2007

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Ubiquitin-binding motif of human DNA polymerase η is required for correct localization

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (8), p.E20-E20; author reply E21

2009

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Novel alternative ribonucleotide excision repair pathways in human cells by DDX3X and specialized DNA polymerases

Nucleic acids research, 2020-11, Vol.48 (20), p.11551

2020

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DROSHA is recruited to DNA damage sites by the MRN complex to promote non-homologous end joining

Journal of cell science, 2021-03, Vol.134 (6)

2021

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UBR5 interacts with the replication fork and protects DNA replication from DNA polymerase η toxicity

Nucleic acids research, 2019-12, Vol.47 (21), p.11268

2019

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Translesion synthesis: Y-family polymerases and the polymerase switch

DNA repair, 2007-07, Vol.6 (7), p.891-899

2007

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RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress

Oncogene, 2016-07, Vol.35 (30), p.4009-4019

2016

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ATR-mediated phosphorylation of DNA polymerase η is needed for efficient recovery from UV damage

The Journal of cell biology, 2011-01, Vol.192 (2), p.219-227

2011

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Regulation of Translesion Synthesis DNA Polymerase η by Monoubiquitination

Molecular cell, 2010-02, Vol.37 (3), p.396-407

2010

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Ribonucleotide incorporation by human DNA polymerase η impacts translesion synthesis and RNase H2 activity

Nucleic acids research, 2017-03, Vol.45 (5), p.2600

2017

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Phosphorylation regulates human polη stability and damage bypass throughout the cell cycle

Nucleic acids research, 2017-09, Vol.45 (16), p.9441

2017

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Chk1 loss creates replication barriers that compromise cell survival independently of excess origin firing

The EMBO journal, 2019-08, Vol.38 (16), p.e101284-n/a

2019

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From R-Loops to G-Quadruplexes: Emerging New Threats for the Replication Fork

Elongating RNA polymerase II and RNA:DNA hybrids hinder fork progression and gene expression at sites of head-on replication-transcription collisions

4-PBA ameliorates cellular homeostasis in fibroblasts from osteogenesis imperfecta patients by enhancing autophagy and stimulating protein secretion

Sex specific regulation of TSPY-Like 2 in the DNA damage response of cancer cells

Homozygous substitution of threonine 191 by proline in polymerase η causes Xeroderma pigmentosum variant

TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism

Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate

The Regulation of DNA Damage Tolerance by Ubiquitin and Ubiquitin-Like Modifiers

Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

Replication of Structured DNA and its implication in epigenetic stability

A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres

Effect of proliferating cell nuclear antigen ubiquitination and chromatin structure on the dynamic properties of the Y-family DNA polymerases

Yeast Rev1 is cell cycle regulated, phosphorylated in response to DNA damage and its binding to chromosomes is dependent upon MEC1

Ubiquitin-binding motif of human DNA polymerase η is required for correct localization

Novel alternative ribonucleotide excision repair pathways in human cells by DDX3X and specialized DNA polymerases

DROSHA is recruited to DNA damage sites by the MRN complex to promote non-homologous end joining

UBR5 interacts with the replication fork and protects DNA replication from DNA polymerase η toxicity

Translesion synthesis: Y-family polymerases and the polymerase switch

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress

ATR-mediated phosphorylation of DNA polymerase η is needed for efficient recovery from UV damage

Regulation of Translesion Synthesis DNA Polymerase η by Monoubiquitination

Ribonucleotide incorporation by human DNA polymerase η impacts translesion synthesis and RNase H2 activity

TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism

Phosphorylation regulates human polη stability and damage bypass throughout the cell cycle

Chk1 loss creates replication barriers that compromise cell survival independently of excess origin firing

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