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Aberrant Wnt signaling in multiple myeloma: molecular mechanisms and targeting options

Leukemia, 2019-05, Vol.33 (5), p.1063-1075

2019

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A loss-of-adhesion CRISPR-Cas9 screening platform to identify cell adhesion-regulatory proteins and signaling pathways

Nature communications, 2022-04, Vol.13 (1), p.2136-2136, Article 2136

2022

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The clinically active BTK inhibitor PCI-32765 targets B-cell receptor– and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia

Blood, 2012-03, Vol.119 (11), p.2590-2594

2012

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What's brewing for MALT1 in lymphoma?

Blood, 2023-12, Vol.142 (23), p.1939

Spaargaren, Marcel

2023

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Identification of the SRC-family tyrosine kinase HCK as a therapeutic target in mantle cell lymphoma

Leukemia, 2021-03, Vol.35 (3), p.881-886

2021

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MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance

Gastroenterology (New York, N.Y. 1943), 2019-10, Vol.157 (4), p.1153-1155.e1

2019

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Heparan sulfate proteoglycans in the control of B cell development and the pathogenesis of multiple myeloma

The FEBS journal, 2013-05, Vol.280 (10), p.2180-2193

2013

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The forkhead transcription factor FOXP1 represses human plasma cell differentiation

Blood, 2015-10, Vol.126 (18), p.2098-2109

2015

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Bruton's Tyrosine Kinase and Phospholipase Cγ2 Mediate Chemokine-Controlled B Cell Migration and Homing

Immunity (Cambridge, Mass.), 2007, Vol.26 (1), p.93-104

2007

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Immune evasion in primary testicular and central nervous system lymphomas: HLA loss rather than 9p24.1/PD-L1/PD-L2 alterations

Blood, 2021-09, Vol.138 (13), p.1194-1197

2021

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Lymphoma dissemination: the other face of lymphocyte homing

Blood, 2007-11, Vol.110 (9), p.3102-3111

2007

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The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma

British journal of cancer, 2019-06, Vol.120 (12), p.1137-1146

2019

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Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis

Cancer research (Chicago, Ill.), 2008-05, Vol.68 (10), p.3655-3661

2008

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The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma

Journal of hematology and oncology, 2021-01, Vol.14 (1), p.11-11, Article 11

2021

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MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas

Blood cancer journal (New York), 2023-03, Vol.13 (1), p.37-37, Article 37

2023

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The oncogenic human B-cell lymphoma MYD88 L265P mutation genocopies activation by phosphorylation at the Toll/interleukin-1 receptor (TIR) domain

Blood cancer journal (New York), 2023-08, Vol.13 (1), p.125-125, Article 125

2023

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Correction to: The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma

Journal of hematology and oncology, 2021-02, Vol.14 (1), p.29-29, Article 29

2021

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Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies

Oncogenesis (New York, NY), 2023-02, Vol.12 (1), p.6-6, Article 6

2023

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Illegitimate WNT Signaling Promotes Proliferation of Multiple Myeloma Cells

Proceedings of the National Academy of Sciences - PNAS, 2004-04, Vol.101 (16), p.6122-6127

2004

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Transcriptional silencing of the Wnt-antagonist DKK1 by promoter methylation is associated with enhanced Wnt signaling in advanced multiple myeloma

PloS one, 2012-02, Vol.7 (2), p.e30359

2012

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The HGF/MET pathway as target for the treatment of multiple myeloma and B-cell lymphomas

Biochimica et biophysica acta, 2010-12, Vol.1806 (2), p.208-219

2010

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AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma

Blood advances, 2020-09, Vol.4 (17), p.4151-4164

2020

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The B Cell Antigen Receptor Controls Integrin Activity through Btk and PLCγ2

The Journal of experimental medicine, 2003-11, Vol.198 (10), p.1539-1550

2003

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CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 status

PloS one, 2013-08, Vol.8 (8), p.e72849-e72849

2013

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Cell surface proteoglycan syndecan-1 mediates hepatocyte growth factor binding and promotes Met signaling in multiple myeloma

Blood, 2002-02, Vol.99 (4), p.1405-1410

2002

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Aberrant Wnt signaling in multiple myeloma: molecular mechanisms and targeting options

A loss-of-adhesion CRISPR-Cas9 screening platform to identify cell adhesion-regulatory proteins and signaling pathways

The clinically active BTK inhibitor PCI-32765 targets B-cell receptor– and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia

What's brewing for MALT1 in lymphoma?

Identification of the SRC-family tyrosine kinase HCK as a therapeutic target in mantle cell lymphoma

MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance

Heparan sulfate proteoglycans in the control of B cell development and the pathogenesis of multiple myeloma

The forkhead transcription factor FOXP1 represses human plasma cell differentiation

Bruton's Tyrosine Kinase and Phospholipase Cγ2 Mediate Chemokine-Controlled B Cell Migration and Homing

Immune evasion in primary testicular and central nervous system lymphomas: HLA loss rather than 9p24.1/PD-L1/PD-L2 alterations

Lymphoma dissemination: the other face of lymphocyte homing

The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma

Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis

The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma

MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas

The oncogenic human B-cell lymphoma MYD88 L265P mutation genocopies activation by phosphorylation at the Toll/interleukin-1 receptor (TIR) domain

Correction to: The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma

Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies

Illegitimate WNT Signaling Promotes Proliferation of Multiple Myeloma Cells

Transcriptional silencing of the Wnt-antagonist DKK1 by promoter methylation is associated with enhanced Wnt signaling in advanced multiple myeloma

The HGF/MET pathway as target for the treatment of multiple myeloma and B-cell lymphomas

AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma

The B Cell Antigen Receptor Controls Integrin Activity through Btk and PLCγ2

CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 status

Cell surface proteoglycan syndecan-1 mediates hepatocyte growth factor binding and promotes Met signaling in multiple myeloma

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