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Evidence for Seeding of beta -Amyloid by Intracerebral Infusion of Alzheimer Brain Extracts in beta -Amyloid Precursor Protein-Transgenic Mice

The Journal of neuroscience, 2000-05, Vol.20 (10), p.3606-3611

2000

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Design and Synthesis of m1-Selective Muscarinic Agonists: (R)-(−)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3‘-Methoxyphenyl)-2-propynyl)- oxime Maleate (CI-1017), a Functionally m1-Selective Muscarinic Agonist

Journal of medicinal chemistry, 1998-07, Vol.41 (14), p.2524-2536

1998

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Identification and characterization of m4 selective muscarinic antagonists

Bioorganic & medicinal chemistry letters, 1998-08, Vol.8 (15), p.1991-1996

1998

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Inhibitors of V‐Type ATPases, Bafilomycin A1 and Concanamycin A, Protect Against β‐Amyloid‐Mediated Effects on 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide (MTT) Reduction

Journal of neurochemistry, 1999-05, Vol.72 (5), p.1939-1947

1999

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The M1 Muscarinic Agonist CI-1017 Facilitates Trace Eyeblink Conditioning in Aging Rabbits and Increases the Excitability of CA1 Pyramidal Neurons

The Journal of neuroscience, 2000-01, Vol.20 (2), p.783-790

2000

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Differential expression of group I metabotropic glutamate receptors (mGluRs) in the rat pheochromocytoma cell line PC12: role of nerve growth factor and ras

Neuroscience letters, 1998-08, Vol.252 (1), p.1-4

1998

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A Structure−Activity Relationship Study of Novel Phenylacetamides Which Are Sodium Channel Blockers

Journal of medicinal chemistry, 1996-03, Vol.39 (7), p.1514-1520

1996

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Synthesis and Sar of bulky 1-azabicyclo[2.2.1]-3-one oximes as muscarinic receptor subtype selective agonists

Life sciences (1973), 1993, Vol.52 (5), p.505-511

1993

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Cognition activators

Medicinal research reviews, 1988-07, Vol.8 (3), p.353-391

1988

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Specific binding of the novel Na+ channel blocker PD85,639 to the alpha subunit of rat brain Na+ channels

Molecular pharmacology, 1993-06, Vol.43 (6), p.955-964

1993

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Acute epididymitis in boys: are antibiotics indicated?

British Journal of Urology, 1997-05, Vol.79 (5), p.797-800

1997

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Substituted 2-Benzothiazolamines as Sodium Flux Inhibitors: Quantitative Structure-Activity Relationships and Anticonvulsant Activity

Journal of pharmaceutical sciences, 1994-10, Vol.83 (10), p.1425-1432

1994

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Characterization of muscarinic agonists in recombinant cell lines

Life sciences (1973), 1993, Vol.52 (5), p.465-472

1993

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Comparison of different substances for subureteric injection in the management of vesicoureteric reflux in children

Canadian journal of urology, 2005-08, Vol.12 (4), p.2774

2005

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Loss of muscarinic M1 receptors with aging in the cerebral cortex of fisher 344 rats

Pharmacology, biochemistry and behavior, 1990-03, Vol.35 (3), p.589-593

1990

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Synthesis and pharmacological evaluation of phenylacetamides as sodium-channel blockers

Journal of medicinal chemistry, 1994-01, Vol.37 (2), p.268-274

1994

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Milameline (CI-979/RU35926): a muscarinic receptor agonist with cognition-activating properties: biochemical and in vivo characterization

The Journal of pharmacology and experimental therapeutics, 1999-11, Vol.291 (2), p.812

1999

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A silica gel plate-based qualitative assay for acetylcholinesterase activity: A mass method to screen for potential inhibitors

Analytical biochemistry, 1991-08, Vol.196 (2), p.439-442

1991

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Next generation tacrine

Neurobiology of aging, 1991-03, Vol.12 (2), p.185-187

1991

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Synthesis of 1,4,7,8,9,10-hexahydro-9-methyl-6-nitropyrido[3,4-f]-quinoxaline-2,3-dione and related quinoxalinediones: characterization of .alpha.-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (and N-methyl-D-aspartate) receptor and anticonvulsant activity

Journal of medicinal chemistry, 1995-09, Vol.38 (19), p.3720-3740

1995

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Cholinergic Agents: Effect of Methyl Substitution in a Series of Arecoline Derivatives on Binding to Muscarinic Acetylcholine Receptors

Journal of pharmaceutical sciences, 1992-10, Vol.81 (10), p.1015-1019

1992

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Formation of antibodies to prostaglandins in the yolk of chicken eggs

Biochemical and biophysical research communications, 1981-10, Vol.102 (3), p.1028-1033

1981

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Identification and Characterization of m1 Selective Muscarinic Receptor Antagonists

Journal of medicinal chemistry, 1999-02, Vol.42 (3), p.356-363

1999

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Preclinical and Phase 1 clinical characterization of CI-979/ RU35926, a novel muscarinic agonist for the treatment of Alzheimer's disease

Life sciences (1973), 1995, Vol.56 (11), p.877-882

1995

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Pediatric kidney stones: Long-term outcomes

Urology (Ridgewood, N.J.), 2006-04, Vol.67 (4), p.812-816

2006

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Evidence for Seeding of beta -Amyloid by Intracerebral Infusion of Alzheimer Brain Extracts in beta -Amyloid Precursor Protein-Transgenic Mice

Design and Synthesis of m1-Selective Muscarinic Agonists: (R)-(−)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3‘-Methoxyphenyl)-2-propynyl)- oxime Maleate (CI-1017), a Functionally m1-Selective Muscarinic Agonist

Identification and characterization of m4 selective muscarinic antagonists

Inhibitors of V‐Type ATPases, Bafilomycin A1 and Concanamycin A, Protect Against β‐Amyloid‐Mediated Effects on 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide (MTT) Reduction

The M1 Muscarinic Agonist CI-1017 Facilitates Trace Eyeblink Conditioning in Aging Rabbits and Increases the Excitability of CA1 Pyramidal Neurons

Differential expression of group I metabotropic glutamate receptors (mGluRs) in the rat pheochromocytoma cell line PC12: role of nerve growth factor and ras

A Structure−Activity Relationship Study of Novel Phenylacetamides Which Are Sodium Channel Blockers

Synthesis and Sar of bulky 1-azabicyclo[2.2.1]-3-one oximes as muscarinic receptor subtype selective agonists

Cognition activators

Specific binding of the novel Na+ channel blocker PD85,639 to the alpha subunit of rat brain Na+ channels

Acute epididymitis in boys: are antibiotics indicated?

Substituted 2-Benzothiazolamines as Sodium Flux Inhibitors: Quantitative Structure-Activity Relationships and Anticonvulsant Activity

Characterization of muscarinic agonists in recombinant cell lines

Comparison of different substances for subureteric injection in the management of vesicoureteric reflux in children

Loss of muscarinic M1 receptors with aging in the cerebral cortex of fisher 344 rats

Synthesis and pharmacological evaluation of phenylacetamides as sodium-channel blockers

Milameline (CI-979/RU35926): a muscarinic receptor agonist with cognition-activating properties: biochemical and in vivo characterization

A silica gel plate-based qualitative assay for acetylcholinesterase activity: A mass method to screen for potential inhibitors

Next generation tacrine

Synthesis of 1,4,7,8,9,10-hexahydro-9-methyl-6-nitropyrido[3,4-f]-quinoxaline-2,3-dione and related quinoxalinediones: characterization of .alpha.-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (and N-methyl-D-aspartate) receptor and anticonvulsant activity

Cholinergic Agents: Effect of Methyl Substitution in a Series of Arecoline Derivatives on Binding to Muscarinic Acetylcholine Receptors

Formation of antibodies to prostaglandins in the yolk of chicken eggs

Identification and Characterization of m1 Selective Muscarinic Receptor Antagonists

Preclinical and Phase 1 clinical characterization of CI-979/ RU35926, a novel muscarinic agonist for the treatment of Alzheimer's disease

Pediatric kidney stones: Long-term outcomes

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