UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Novel lung imaging biomarkers and skin gene expression subsetting in dasatinib treatment of systemic sclerosis-associated interstitial lung disease

PloS one, 2017-11, Vol.12 (11), p.e0187580

2017

Volltextzugriff (PDF)

Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9)

ACS medicinal chemistry letters, 2020-09, Vol.11 (9), p.1751-1758

2020

Volltextzugriff (PDF)

Rapid Activation of Glutamate Cysteine Ligase following Oxidative Stress

The Journal of biological chemistry, 2010-05, Vol.285 (21), p.16116-16124

2010

Volltextzugriff (PDF)

The biology of p38 kinase: a central role in inflammation

Current topics in medicinal chemistry, 2005-09, Vol.5 (10), p.921-928

Schieven, Gary L

2005

Volltextzugriff (PDF)

The p38α Kinase Plays a Central Role In Inflammation

Current topics in medicinal chemistry, 2009-08, Vol.9 (11), p.1038-1048

Schieven, Gary

2009

Volltextzugriff (PDF)

Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation

Blood, 2008-02, Vol.111 (3), p.1366-1377

2008

Volltextzugriff (PDF)

Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization

Journal of medicinal chemistry, 2022-02, Vol.65 (4), p.3518-3538

2022

Volltextzugriff (PDF)

Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology

ACS medicinal chemistry letters, 2024-02, Vol.15 (2), p.189-196

2024

Volltextzugriff (PDF)

Identification of 2‑Pyridinylindole-Based Dual Antagonists of Toll-like Receptors 7 and 8 (TLR7/8)

ACS medicinal chemistry letters, 2022-05, Vol.13 (5), p.812-818

2022

Volltextzugriff (PDF)

Identification of a Potent, Selective, and Efficacious Phosphatidylinositol 3‑Kinase δ (PI3Kδ) Inhibitor for the Treatment of Immunological Disorders

Journal of medicinal chemistry, 2017-06, Vol.60 (12), p.5193-5208

2017

Volltextzugriff (PDF)

Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors

Bioorganic & medicinal chemistry letters, 2017-07, Vol.27 (14), p.3101-3106

2017

Volltextzugriff (PDF)

Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis

ACS medicinal chemistry letters, 2019-03, Vol.10 (3), p.306-311

2019

Volltextzugriff (PDF)

Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors

Bioorganic & medicinal chemistry letters, 2014-12, Vol.24 (24), p.5721-5726

2014

Volltextzugriff (PDF)

Design, Synthesis, and Anti-inflammatory Properties of Orally Active 4-(Phenylamino)-pyrrolo[2,1-f][1,2,4]triazine p38α Mitogen-Activated Protein Kinase Inhibitors

Journal of medicinal chemistry, 2008-01, Vol.51 (1), p.4-16

2008

Volltextzugriff (PDF)

The identification of novel p38α isoform selective kinase inhibitors having an unprecedented p38α binding mode

Bioorganic & medicinal chemistry letters, 2013-07, Vol.23 (14), p.4120-4126

2013

Volltextzugriff (PDF)

Synthesis and evaluation of carbamoylmethylene linked prodrugs of BMS-582949, a clinical p38α inhibitor

Bioorganic & medicinal chemistry letters, 2013-05, Vol.23 (10), p.3028-3033

2013

Volltextzugriff (PDF)

Benzothiazole based inhibitors of p38α MAP kinase

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (6), p.1874-1879

2008

Volltextzugriff (PDF)

Utilization of a nitrogen–sulfur nonbonding interaction in the design of new 2-aminothiazol-5-yl-pyrimidines as p38α MAP kinase inhibitors

Bioorganic & medicinal chemistry letters, 2010-10, Vol.20 (19), p.5864-5868

2010

Volltextzugriff (PDF)

Pyrazolo-pyrimidines: A novel heterocyclic scaffold for potent and selective p38α inhibitors

Bioorganic & medicinal chemistry, 2008-04, Vol.18 (8), p.2652-2657

2008

Volltextzugriff (PDF)

Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56(lck) inhibitors

Bioorganic & medicinal chemistry letters, 2003-08, Vol.13 (15), p.2587-2590

2003

Volltextzugriff (PDF)

1 – 25 von 129

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(126)
Mit Volltextzugriff
(113)

Publikationsform

Artikel
(128)
Buchkapitel
(1)

Sprache

Englisch
(129)

Erscheinungsjahr

n.n

Thema

Science & Technology
(76)
Life Sciences & Biomedicine
(70)
Humans
(61)
Biological And Medical Sciences
(53)
Animals
(36)
Chemistry, Medicinal
(32)
Pharmacology & Pharmacy
(32)
Fundamental And Applied Biological Sciences. Psychology
(28)
Phosphorylation
(26)
Medical Sciences
(25)
Structure-Activity Relationship
(25)
Mice
(24)
Pharmacology. Drug Treatments
(21)
Physical Sciences
(20)
Protein-Tyrosine Kinases - Metabolism
(20)
Signal Transduction
(20)
Tyrosine - Metabolism
(19)
Chemistry
(18)
Chemistry, Organic
(18)
Models, Molecular
(18)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Novel lung imaging biomarkers and skin gene expression subsetting in dasatinib treatment of systemic sclerosis-associated interstitial lung disease

Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9)

Rapid Activation of Glutamate Cysteine Ligase following Oxidative Stress

The biology of p38 kinase: a central role in inflammation

The p38α Kinase Plays a Central Role In Inflammation

Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation

Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization

Discovery of N-(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays

Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology

Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology

Identification of 2‑Pyridinylindole-Based Dual Antagonists of Toll-like Receptors 7 and 8 (TLR7/8)

Identification of a Potent, Selective, and Efficacious Phosphatidylinositol 3‑Kinase δ (PI3Kδ) Inhibitor for the Treatment of Immunological Disorders

Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors

Discovery of 4-(5-(Cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-N-propylpyrrolo[1,2-f][1,2,4]triazine-6-carboxamide (BMS-582949), a Clinical p38α MAP Kinase Inhibitor for the Treatment of Inflammatory Diseases

Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis

Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors

Discovery of ((4-(5-(Cyclopropylcarbamoyl)-2-methylphenylamino)-5-methylpyrrolo[1,2-f][1,2,4]triazine-6-carbonyl)(propyl)carbamoyloxy)methyl-2-(4-(phosphonooxy)phenyl)acetate (BMS-751324), a Clinical Prodrug of p38α MAP Kinase Inhibitor

Design, Synthesis, and Anti-inflammatory Properties of Orally Active 4-(Phenylamino)-pyrrolo[2,1-f][1,2,4]triazine p38α Mitogen-Activated Protein Kinase Inhibitors

The identification of novel p38α isoform selective kinase inhibitors having an unprecedented p38α binding mode

Synthesis and evaluation of carbamoylmethylene linked prodrugs of BMS-582949, a clinical p38α inhibitor

Benzothiazole based inhibitors of p38α MAP kinase

Utilization of a nitrogen–sulfur nonbonding interaction in the design of new 2-aminothiazol-5-yl-pyrimidines as p38α MAP kinase inhibitors

Pyrazolo-pyrimidines: A novel heterocyclic scaffold for potent and selective p38α inhibitors

Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56(lck) inhibitors

Suchergebnisse filtern