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Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions

The Journal of neuroscience, 2013-08, Vol.33 (32), p.12915-12928

2013

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Bone density, strength, and formation in adult cathepsin K (−/−) mice

Bone (New York, N.Y.), 2009-02, Vol.44 (2), p.199-207

2009

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ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death

Cell death and differentiation, 2007-02, Vol.14 (5), p.1040-1049

2007

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Cathepsin F mutations cause Type B Kufs disease, an adult-onset neuronal ceroid lipofuscinosis

Human molecular genetics, 2013-04, Vol.22 (7), p.1417-1423

2013

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Serum Starvation Induces BACE1 Processing and Secretion

Current Alzheimer research, 2017-01, Vol.14 (4), p.453-459

2017

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ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death

Cell death and differentiation, 2007-05, Vol.14 (5), p.1040-1049

2007

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The Bone Lining Cell: Its Role in Cleaning Howship's Lacunae and Initiating Bone Formation

Journal of bone and mineral research, 2002-01, Vol.17 (1), p.77-90

2002

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Redundancy and specificity of the metalloprotease system mediating oncogenic NOTCH1 activation in T-ALL

Leukemia, 2011-10, Vol.25 (10), p.1564-1569

2011

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The “A Disintegrin And Metalloproteases” ADAM10 and ADAM17: Novel drug targets with therapeutic potential?

European journal of cell biology, 2011-06, Vol.90 (6), p.527-535

2011

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Disruption of the Cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation

Circulation (New York, N.Y.), 2006-01, Vol.113 (1), p.98-107

2006

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Tubular proteinuria in mice and humans lacking the intrinsic lysosomal protein SCARB2/Limp-2

American journal of physiology. Renal physiology, 2011-06, Vol.300 (6), p.F1437-F1447

2011

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Enzyme replacement therapy for alpha-mannosidosis: 12 months follow-up of a single centre, randomised, multiple dose study

Journal of inherited metabolic disease, 2013-11, Vol.36 (6), p.1015-1024

2013

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Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells

The EMBO journal, 1995-08, Vol.14 (15), p.3599-3608

1995

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Cathepsin L is involved in cathepsin D processing and regulation of apoptosis in A549 human lung epithelial cells

Biological chemistry, 2004-07, Vol.385 (7), p.665-670

2004

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Cathepsin K deficiency in pycnodysostosis results in accumulation of non-digested phagocytosed collagen in fibroblasts

Calcified tissue international, 2003-10, Vol.73 (4), p.380-386

2003

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LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice

Human molecular genetics, 2003-03, Vol.12 (6), p.631-646

2003

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Cathepsin K Activity-dependent Regulation of Osteoclast Actin Ring Formation and Bone Resorption

The Journal of biological chemistry, 2009-01, Vol.284 (4), p.2584-2592

2009

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Inhibition of ADAM10-mediated CX3CL1 shedding promotes survival and cardiac function early after myocardial infarction

European heart journal, 2023-11, Vol.44 (Supplement_2)

2023

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Overlapping functions of lysosomal acid phosphatase (LAP) and tartrate-resistant acid phosphatase (Acp5) revealed by doubly deficient mice

Development (Cambridge), 2001-12, Vol.128 (23), p.4899-4910

2001

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Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina

Proceedings of the National Academy of Sciences - PNAS, 2019-11, Vol.116 (47), p.23724-23734

2019

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Surface CD107a/LAMP-1 protects natural killer cells from degranulation-associated damage

Blood, 2013-08, Vol.122 (8), p.1411-1418

2013

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Cathepsin D is up‐regulated in inflammatory bowel disease macrophages

Clinical and experimental immunology, 2004-04, Vol.136 (1), p.157-167

2004

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ADAM10 Mediates E-Cadherin Shedding and Regulates Epithelial Cell-Cell Adhesion, Migration, and β-Catenin Translocation

Proceedings of the National Academy of Sciences - PNAS, 2005-06, Vol.102 (26), p.9182-9187

2005

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Role for Rab7 in maturation of late autophagic vacuoles

Journal of cell science, 2004-09, Vol.117 (Pt 20), p.4837-4848

2004

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Calvarial osteoclasts express a higher level of tartrate-resistant acid phosphatase than long bone osteoclasts and activation does not depend on cathepsin K or L activity

Calcified tissue international, 2006-10, Vol.79 (4), p.245-254

2006

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Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions

Bone density, strength, and formation in adult cathepsin K (−/−) mice

ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death

Cathepsin F mutations cause Type B Kufs disease, an adult-onset neuronal ceroid lipofuscinosis

Serum Starvation Induces BACE1 Processing and Secretion

ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death

The Bone Lining Cell: Its Role in Cleaning Howship's Lacunae and Initiating Bone Formation

Redundancy and specificity of the metalloprotease system mediating oncogenic NOTCH1 activation in T-ALL

The “A Disintegrin And Metalloproteases” ADAM10 and ADAM17: Novel drug targets with therapeutic potential?

Disruption of the Cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation

Tubular proteinuria in mice and humans lacking the intrinsic lysosomal protein SCARB2/Limp-2

Enzyme replacement therapy for alpha-mannosidosis: 12 months follow-up of a single centre, randomised, multiple dose study

Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells

Cathepsin L is involved in cathepsin D processing and regulation of apoptosis in A549 human lung epithelial cells

Cathepsin K deficiency in pycnodysostosis results in accumulation of non-digested phagocytosed collagen in fibroblasts

LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice

Cathepsin K Activity-dependent Regulation of Osteoclast Actin Ring Formation and Bone Resorption

Inhibition of ADAM10-mediated CX3CL1 shedding promotes survival and cardiac function early after myocardial infarction

Overlapping functions of lysosomal acid phosphatase (LAP) and tartrate-resistant acid phosphatase (Acp5) revealed by doubly deficient mice

Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina

Surface CD107a/LAMP-1 protects natural killer cells from degranulation-associated damage

Cathepsin D is up‐regulated in inflammatory bowel disease macrophages

ADAM10 Mediates E-Cadherin Shedding and Regulates Epithelial Cell-Cell Adhesion, Migration, and β-Catenin Translocation

Role for Rab7 in maturation of late autophagic vacuoles

Calvarial osteoclasts express a higher level of tartrate-resistant acid phosphatase than long bone osteoclasts and activation does not depend on cathepsin K or L activity

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