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Galectin 3 as a guardian of the tumor microenvironment

Biochimica et biophysica acta, 2016-03, Vol.1863 (3), p.427-437

Ruvolo, Peter P.

2016

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Role of protein phosphatases in the cancer microenvironment

Biochimica et biophysica acta. Molecular cell research, 2019-01, Vol.1866 (1), p.144-152

Ruvolo, Peter P.

2019

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The broken “Off” switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillance

BBA clinical, 2016-12, Vol.6, p.87-99

Ruvolo, Peter P.

2016

Volltextzugriff (PDF)

Intracellular signal transduction pathways activated by ceramide and its metabolites

Pharmacological research, 2003-05, Vol.47 (5), p.383-392

Ruvolo, Peter P.

2003

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LGALS1 acts as a pro-survival molecule in AML

Biochimica et biophysica acta. Molecular cell research, 2020-10, Vol.1867 (10), p.118785-118785, Article 118785

2020

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Low expression of PP2A regulatory subunit B55α is associated with T308 phosphorylation of AKT and shorter complete remission duration in acute myeloid leukemia patients

Leukemia, 2011-11, Vol.25 (11), p.1711-1717

2011

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Roles of the Ras Raf MEK ERK pathway in leukemia therapy

Leukemia, 2011-07, Vol.25 (7), p.1080-1094

2011

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Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K PTEN Akt mTOR pathway

Leukemia, 2011-07, Vol.25 (7), p.1064-1079

2011

Volltextzugriff (PDF)

Phosphorylation of Bcl2 and regulation of apoptosis

Leukemia, 2001-04, Vol.15 (4), p.515-522

2001

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Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

Cancer cell, 2006-11, Vol.10 (5), p.375-388

2006

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AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill FLT3 -ITD acute myeloid leukemia

Haematologica (Roma), 2022-06, Vol.107 (6), p.1311

2022

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Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival

Haematologica (Roma), 2018-05, Vol.103 (5), p.810

2018

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Combination of galectin inhibitor GCS-100 and BH3 mimetics eliminates both p53 wild type and p53 null AML cells

Biochimica et biophysica acta, 2016-04, Vol.1863 (4), p.562-571

2016

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TP53/miR-34a-associated signaling targets SERPINE1 expression in human pancreatic cancer

Aging (Albany, NY.), 2020-01, Vol.12 (3), p.2777-2797

2020

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Anexelekto/MER tyrosine kinase inhibitor ONO-7475 arrests growth and kills FMS-like tyrosine kinase 3-internal tandem duplication mutant acute myeloid leukemia cells by diverse mechanisms

Haematologica (Roma), 2017-12, Vol.102 (12), p.2048

2017

Volltextzugriff (PDF)

Ceramide regulates cellular homeostasis via diverse stress signaling pathways

Leukemia, 2001-08, Vol.15 (8), p.1153-1160

RUVOLO, P. P

2001

Volltextzugriff (PDF)

Retraction Note: MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex

Leukemia, 2024-09, Vol.38 (9), p.2072-2072

2024

Volltextzugriff (PDF)

Inhibition of Mcl-1 with the pan–Bcl-2 family inhibitor (–)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia

Blood, 2015-07, Vol.126 (3), p.363-372

2015

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The potential of enzastaurin to enhance platelet aggregation and growth factor secretion: implications for cancer cell survival

Journal of thrombosis and haemostasis, 2015-08, Vol.13 (8), p.1514-1520

2015

Volltextzugriff (PDF)

Preclinical and Early Clinical Evaluation of the Oral AKT Inhibitor, MK-2206, for the Treatment of Acute Myelogenous Leukemia

Clinical cancer research, 2014-04, Vol.20 (8), p.2226-2235

2014

Volltextzugriff (PDF)

MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex

Leukemia, 2012-04, Vol.26 (4), p.778-787

2012

Volltextzugriff (PDF)

The Herculean task of killing cancer cells: Suppression of FOXO3A in acute leukemia involves a hydra of multiple survival kinases

Cell cycle (Georgetown, Tex.), 2012-07, Vol.11 (14), p.2589-2589

Ruvolo, Peter P.

2012

Volltextzugriff (PDF)

Targeting PKC-mediated signal transduction pathways using enzastaurin to promote apoptosis in acute myeloid leukemia-derived cell lines and blast cells

Journal of cellular biochemistry, 2011-06, Vol.112 (6), p.1696-1707

2011

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Atg7 suppression enhances chemotherapeutic agent sensitivity and overcomes stroma-mediated chemoresistance in acute myeloid leukemia

Blood, 2016-09, Vol.128 (9), p.1260-1269

2016

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Galectin 3 as a guardian of the tumor microenvironment

Role of protein phosphatases in the cancer microenvironment

The broken “Off” switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillance

Intracellular signal transduction pathways activated by ceramide and its metabolites

Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia

LGALS1 acts as a pro-survival molecule in AML

Low expression of PP2A regulatory subunit B55α is associated with T308 phosphorylation of AKT and shorter complete remission duration in acute myeloid leukemia patients

Roles of the Ras Raf MEK ERK pathway in leukemia therapy

Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K PTEN Akt mTOR pathway

Phosphorylation of Bcl2 and regulation of apoptosis

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill FLT3 -ITD acute myeloid leukemia

Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival

Combination of galectin inhibitor GCS-100 and BH3 mimetics eliminates both p53 wild type and p53 null AML cells

TP53/miR-34a-associated signaling targets SERPINE1 expression in human pancreatic cancer

Anexelekto/MER tyrosine kinase inhibitor ONO-7475 arrests growth and kills FMS-like tyrosine kinase 3-internal tandem duplication mutant acute myeloid leukemia cells by diverse mechanisms

Ceramide regulates cellular homeostasis via diverse stress signaling pathways

Retraction Note: MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex

Inhibition of Mcl-1 with the pan–Bcl-2 family inhibitor (–)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia

The potential of enzastaurin to enhance platelet aggregation and growth factor secretion: implications for cancer cell survival

Preclinical and Early Clinical Evaluation of the Oral AKT Inhibitor, MK-2206, for the Treatment of Acute Myelogenous Leukemia

MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex

The Herculean task of killing cancer cells: Suppression of FOXO3A in acute leukemia involves a hydra of multiple survival kinases

Targeting PKC-mediated signal transduction pathways using enzastaurin to promote apoptosis in acute myeloid leukemia-derived cell lines and blast cells

Atg7 suppression enhances chemotherapeutic agent sensitivity and overcomes stroma-mediated chemoresistance in acute myeloid leukemia

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