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The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design

Nature, 2006-09, Vol.443 (7107), p.45-49

2006

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Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (46), p.17736-17741

2008

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Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of 1957

Proceedings of the National Academy of Sciences - PNAS, 2009-10, Vol.106 (40), p.17175-17180

2009

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Novel Cambinol Analogs as Sirtuin Inhibitors: Synthesis, Biological Evaluation, and Rationalization of Activity

Journal of medicinal chemistry, 2009-05, Vol.52 (9), p.2673-2682

2009

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Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase

Nature communications, 2010-11, Vol.1 (8), p.113-113, Article 113

2010

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Evolving complexities of influenza virus and its receptors

Trends in microbiology (Regular ed.), 2008-04, Vol.16 (4), p.149-157

2008

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Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (5), p.1954-1959

2010

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Contribution of NS1 Effector Domain Dimerization to Influenza A Virus Replication and Virulence

Journal of Virology, 2012-12, Vol.86 (23), p.13095-13098

2012

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Analysis of residues near the fusion peptide in the influenza hemagglutinin structure for roles in triggering membrane fusion

Virology (New York, N.Y.), 2008-01, Vol.370 (2), p.403-414

2008

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Comparison of the receptor binding properties of contemporary swine isolates and early human pandemic H1N1 isolates (Novel 2009 H1N1)

Virology (New York, N.Y.), 2011-05, Vol.413 (2), p.169-182

2011

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A transient homotypic interaction model for the influenza A virus NS1 protein effector domain

PloS one, 2011-03, Vol.6 (3), p.e17946-e17946

2011

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Structure of an avian influenza A virus NS1 protein effector domain

Virology (New York, N.Y.), 2008-08, Vol.378 (1), p.1-5

2008

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Molecular Determinants within the Surface Proteins Involved in the Pathogenicity of H5N1 Influenza Viruses in Chickens

Journal of Virology, 2004-09, Vol.78 (18), p.9954-9964

2004

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Structural basis for a class of nanomolar influenza A neuraminidase inhibitors

Scientific reports, 2013-10, Vol.3 (1), p.2871-2871, Article 2871

2013

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Combinatorial Effect of Two Framework Mutations (E119V and I222L) in the Neuraminidase Active Site of H3N2 Influenza Virus on Resistance to Oseltamivir

Antimicrobial Agents and Chemotherapy, 2011-06, Vol.55 (6), p.2942-2952

2011

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Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility

Organic & biomolecular chemistry, 2012-11, Vol.10 (43), p.8628-8639

2012

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Exploring the Interactions of Unsaturated Glucuronides with Influenza Virus Sialidase

Journal of medicinal chemistry, 2012-10, Vol.55 (20), p.8963-8968

2012

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Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants

Nature, 2008-06, Vol.453 (7199), p.1258-1261

2008

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Characteristics of arbidol-resistant mutants of influenza virus: Implications for the mechanism of anti-influenza action of arbidol

Antiviral research, 2009-02, Vol.81 (2), p.132-140

2009

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The Complex of a Designer Antibiotic with a Model Aminoacyl Site of the 30S Ribosomal Subunit Revealed by X-ray Crystallography

Journal of the American Chemical Society, 2003-03, Vol.125 (12), p.3410-3411

2003

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S-Adenosyl-L-methionine:Hydroxide Adenosyltransferase: A SAM Enzyme

Angewandte Chemie (International ed.), 2008-07, Vol.47 (29), p.5357-5361

2008

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Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors

Nature, 2006-11, Vol.444 (7117), p.378-382

2006

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Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding

Nucleic acids research, 2005-01, Vol.33 (17), p.5677-5690

2005

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Infectivity Studies of Influenza Virus Hemagglutinin Receptor Binding Site Mutants in Mice

Journal of Virology, 2008-05, Vol.82 (10), p.5079-5083

2008

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The Crystal Structure of Citrate Synthase from the Hyperthermophilic Archaeon Pyrococcus furiosus at 1.9 Å Resolution

Biochemistry (Easton), 1997-08, Vol.36 (33), p.9983-9994

1997

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The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design

Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion

Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of 1957

Novel Cambinol Analogs as Sirtuin Inhibitors: Synthesis, Biological Evaluation, and Rationalization of Activity

Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase

Evolving complexities of influenza virus and its receptors

Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein

Contribution of NS1 Effector Domain Dimerization to Influenza A Virus Replication and Virulence

Analysis of residues near the fusion peptide in the influenza hemagglutinin structure for roles in triggering membrane fusion

Comparison of the receptor binding properties of contemporary swine isolates and early human pandemic H1N1 isolates (Novel 2009 H1N1)

A transient homotypic interaction model for the influenza A virus NS1 protein effector domain

Structure of an avian influenza A virus NS1 protein effector domain

Molecular Determinants within the Surface Proteins Involved in the Pathogenicity of H5N1 Influenza Viruses in Chickens

Structural basis for a class of nanomolar influenza A neuraminidase inhibitors

Combinatorial Effect of Two Framework Mutations (E119V and I222L) in the Neuraminidase Active Site of H3N2 Influenza Virus on Resistance to Oseltamivir

Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility

Exploring the Interactions of Unsaturated Glucuronides with Influenza Virus Sialidase

Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants

Characteristics of arbidol-resistant mutants of influenza virus: Implications for the mechanism of anti-influenza action of arbidol

The Complex of a Designer Antibiotic with a Model Aminoacyl Site of the 30S Ribosomal Subunit Revealed by X-ray Crystallography

S-Adenosyl-L-methionine:Hydroxide Adenosyltransferase: A SAM Enzyme

Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors

Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding

Infectivity Studies of Influenza Virus Hemagglutinin Receptor Binding Site Mutants in Mice

The Crystal Structure of Citrate Synthase from the Hyperthermophilic Archaeon Pyrococcus furiosus at 1.9 Å Resolution

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