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Induced pluripotent stem cells in disease modelling and drug discovery

Nature reviews. Genetics, 2019-07, Vol.20 (7), p.377

2019

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Breaching the basement membrane: who, when and how?

Trends in cell biology, 2008-11, Vol.18 (11), p.560-574

2008

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Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

Nature medicine, 2015-09, Vol.21 (9), p.989-997

2015

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Reconstruction of complex single-cell trajectories using CellRouter

Nature communications, 2018-03, Vol.9 (1), p.892-13, Article 892

2018

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Navigating ECM barriers at the invasive front: the cancer cell-stroma interface

Annual review of cell and developmental biology, 2009-11, Vol.25 (1), p.567-595

2009

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Engineering Hematopoietic Stem Cells: Lessons from Development

Cell stem cell, 2016-06, Vol.18 (6), p.707-720

2016

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Developmental regulation of myeloerythroid progenitor function by the Lin28b-let-7-Hmga2 axis

The Journal of experimental medicine, 2016-07, Vol.213 (8), p.1497-1512

2016

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A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition

The Journal of cell biology, 2011-10, Vol.195 (3), p.417-433

2011

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MT1-MMP-Dependent Control of Skeletal Stem Cell Commitment via a β1-Integrin/YAP/TAZ Signaling Axis

Developmental cell, 2013-05, Vol.25 (4), p.402-416

2013

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Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression

Nature communications, 2024-03, Vol.15 (1), p.1987-1987, Article 1987

2024

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Snail1-dependent p53 repression regulates expansion and activity of tumour-initiating cells in breast cancer

Nature cell biology, 2016-11, Vol.18 (11), p.1221

2016

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A nanobody targeting the LIN28: let-7 interaction fragment of TUT4 blocks uridylation of let-7

Proceedings of the National Academy of Sciences - PNAS, 2020-03, Vol.117 (9), p.4653-4663

2020

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Severe Tumor Lysis Syndrome and Acute Pulmonary Edema Requiring Extracorporeal Membrane Oxygenation Following Initiation of Chemotherapy for Metastatic Alveolar Rhabdomyosarcoma

Pediatric blood & cancer, 2016-05, Vol.63 (5), p.928-930

2016

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The developmental stage of the hematopoietic niche regulates lineage in MLL- rearranged leukemia

The Journal of experimental medicine, 2019-03, Vol.216 (3), p.527-538

2019

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Response Evaluation Criteria in Solid Tumors (RECIST) following neoadjuvant chemotherapy in osteosarcoma

Pediatric blood & cancer, 2018-04, Vol.65 (4), p.n/a

2018

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Hepatocyte-Derived Snail1 Propagates Liver Fibrosis Progression

Molecular and Cellular Biology, 2011-06, Vol.31 (12), p.2392-2403

2011

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Pulmonary fibroblasts mobilize the membrane-tethered matrix metalloprotease, MT1-MMP, to destructively remodel and invade interstitial type I collagen barriers

American journal of physiology. Lung cellular and molecular physiology, 2011-11, Vol.301 (5), p.L683-L692

2011

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Fibronectin fibrillogenesis regulates three-dimensional neovessel formation

Genes & development, 2008-05, Vol.22 (9), p.1231-1243

2008

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Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis

Cell reports (Cambridge), 2022-04, Vol.39 (1), p.110587-110587, Article 110587

2022

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Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence

The Journal of experimental medicine, 2015-05, Vol.212 (5), p.633-648

2015

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MT1-MMP controls human mesenchymal stem cell trafficking and differentiation

Blood, 2010-01, Vol.115 (2), p.221-229

2010

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Ewing Sarcoma of the Kidney: Case Series and Literature Review of an Often Overlooked Entity in the Diagnosis of Primary Renal Tumors

Urology (Ridgewood, N.J.), 2013-02, Vol.81 (2), p.347-353

2013

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Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

The Journal of cell biology, 2009-02, Vol.184 (3), p.399-408

2009

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MT1-MMP–Dependent Remodeling of Cardiac Extracellular Matrix Structure and Function Following Myocardial Infarction

The American journal of pathology, 2012-05, Vol.180 (5), p.1863-1878

2012

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Haematopoietic stem and progenitor cells from human pluripotent stem cells

Nature (London), 2017-05, Vol.545 (7655), p.432-438

2017

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Induced pluripotent stem cells in disease modelling and drug discovery

Breaching the basement membrane: who, when and how?

Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

Reconstruction of complex single-cell trajectories using CellRouter

Navigating ECM barriers at the invasive front: the cancer cell-stroma interface

Engineering Hematopoietic Stem Cells: Lessons from Development

Developmental regulation of myeloerythroid progenitor function by the Lin28b-let-7-Hmga2 axis

A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition

MT1-MMP-Dependent Control of Skeletal Stem Cell Commitment via a β1-Integrin/YAP/TAZ Signaling Axis

Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression

Snail1-dependent p53 repression regulates expansion and activity of tumour-initiating cells in breast cancer

A nanobody targeting the LIN28: let-7 interaction fragment of TUT4 blocks uridylation of let-7

Severe Tumor Lysis Syndrome and Acute Pulmonary Edema Requiring Extracorporeal Membrane Oxygenation Following Initiation of Chemotherapy for Metastatic Alveolar Rhabdomyosarcoma

The developmental stage of the hematopoietic niche regulates lineage in MLL- rearranged leukemia

Response Evaluation Criteria in Solid Tumors (RECIST) following neoadjuvant chemotherapy in osteosarcoma

Hepatocyte-Derived Snail1 Propagates Liver Fibrosis Progression

Pulmonary fibroblasts mobilize the membrane-tethered matrix metalloprotease, MT1-MMP, to destructively remodel and invade interstitial type I collagen barriers

Fibronectin fibrillogenesis regulates three-dimensional neovessel formation

Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis

Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence

MT1-MMP controls human mesenchymal stem cell trafficking and differentiation

Ewing Sarcoma of the Kidney: Case Series and Literature Review of an Often Overlooked Entity in the Diagnosis of Primary Renal Tumors

Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

MT1-MMP–Dependent Remodeling of Cardiac Extracellular Matrix Structure and Function Following Myocardial Infarction

Haematopoietic stem and progenitor cells from human pluripotent stem cells

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